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Michael J. Boyd
Michael J. Boyd
Medicinal Chemist, Vertex Pharmaceuticals
Verified email at vrtx.com
Title
Cited by
Cited by
Year
Discovery of a novel, first-in-class, orally bioavailable azaindole inhibitor (VX-787) of influenza PB2
MP Clark, MW Ledeboer, I Davies, RA Byrn, SM Jones, E Perola, A Tsai, ...
Journal of medicinal chemistry 57 (15), 6668-6678, 2014
2212014
Discovery of a potent and selective prostaglandin D2 receptor antagonist,[(3 R)-4-(4-chloro-benzyl)-7-fluoro-5-(methylsulfonyl)-1, 2, 3, 4-tetrahydrocyclopenta [b] indol-3-yl …
CF Sturino, G O'Neill, N Lachance, M Boyd, C Berthelette, M Labelle, L Li, ...
Journal of medicinal chemistry 50 (4), 794-806, 2007
2042007
Battery charger for cellular phone, having speaker
SY Yi
US Patent 6,509,716, 2003
812003
Vehicle lamp housing
R Woolley, E Lucas, D Carbis, D Park, M Boyd
US Patent App. 29/330,138, 2009
592009
Court
MP Clark, MW Ledeboer, I Davies, RA Byrn, SM Jones, E Perola, A Tsai, ...
JJ, Deng, H., Duffy, JP, Dorsch, WA, Farmer, LJ, Gao, H., Gu, W., Jackson, K …, 2014
532014
Application of the photoredox coupling of trifluoroborates and aryl bromides to analog generation using continuous flow
TJ DeLano, UK Bandarage, N Palaychuk, J Green, MJ Boyd
The Journal of Organic Chemistry 81 (24), 12525-12531, 2016
522016
Cyclopentanoindoles, compositions containing such compounds and methods of treatment
M Labelle, C Sturino, B Roy, C Berthelette, M Boyd, N LaChance, ...
US Patent 6,410,583, 2002
522002
Discovery of 4-{1-[({1-[4-(trifluoromethyl) benzyl]-1H-indol-7-yl} carbonyl) amino] cyclopropyl} benzoic acid (MF-766), a highly potent and selective EP4 antagonist for …
J Colucci, M Boyd, C Berthelette, JF Chiasson, Z Wang, Y Ducharme, ...
Bioorganic & Medicinal Chemistry Letters 20 (12), 3760-3763, 2010
402010
Stereoselective Synthesis of a Thymine Derivative of (S)-2-Hydroxy-4-(2-aminophenyl)butanoic Acid. A Novel Building Block for the Synthesis of Aromatic Peptidic Nucleic …
YS Tsantrizos, JF Lunetta, M Boyd, LD Fader, MC Wilson
The Journal of Organic Chemistry 62 (16), 5451-5457, 1997
391997
C–H Functionalization of heteroarenes using unactivated alkyl halides through visible-light photoredox catalysis under basic conditions
NB Bissonnette, MJ Boyd, GD May, S Giroux, P Nuhant
The Journal of Organic Chemistry 83 (18), 10933-10940, 2018
382018
Synthesis of cycloalkyl substituted 7-azaindoles via photoredox nickel dual catalytic cross-coupling in batch and continuous flow
N Palaychuk, TJ DeLano, MJ Boyd, J Green, UK Bandarage
Organic letters 18 (23), 6180-6183, 2016
382016
Generation of Diversity Sets with High sp3 Fraction Using the Photoredox Coupling of Organotrifluoroborates and Organosilicates with Heteroaryl/Aryl Bromides in …
KD Raynor, GD May, UK Bandarage, MJ Boyd
The Journal of Organic Chemistry 83 (3), 1551-1557, 2018
372018
Isosteric replacements of the carboxylic acid of drug candidate VX-787: Effect of charge on antiviral potency and kinase activity of azaindole-based influenza PB2 inhibitors
MJ Boyd, UK Bandarage, H Bennett, RR Byrn, I Davies, W Gu, M Jacobs, ...
Bioorganic & medicinal chemistry letters 25 (9), 1990-1994, 2015
372015
Inhibitors of influenza viruses replication
PS Charifson, MP Clark, UK Bandarage, RS Bethiel, H Deng, I Davies, ...
US Patent App. 13/327,206, 2012
342012
A novel series of potent and selective EP4 receptor ligands: Facile modulation of agonism and antagonism
MJ Boyd, C Berthelette, JF Chiasson, P Clark, J Colucci, D Denis, Y Han, ...
Bioorganic & medicinal chemistry letters 21 (1), 484-487, 2011
342011
Backbone modifications of aromatic peptide nucleic acid (APNA) monomers and their hybridization properties with DNA and RNA
LD Fader, M Boyd, YS Tsantrizos
The Journal of Organic Chemistry 66 (10), 3372-3379, 2001
332001
Nickel-catalyzed electrochemical reductive homocouplings of aryl and heteroaryl halides: a useful route to symmetrical biaryls
R Rahil, S Sengmany, E Le Gall, E Leonel
Synthesis 50 (01), 146-154, 2018
322018
Catalysis of Ester Aminolysis by Cyclodextrins. The Reaction of Alkylamines with p-Nitrophenyl Alkanoates
TA Gadosy, MJ Boyd, OS Tee
The Journal of Organic Chemistry 65 (21), 6879-6889, 2000
322000
Vehicle grille
R Woolley, E Lucas, D Carbis, D Park, M Boyd
US Patent App. 29/333,100, 2009
312009
Vehicle front fender
R Woolley, E Lucas, D Carbis, D Park, M Boyd
US Patent App. 29/306,435, 2009
312009
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