IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress MJ Grey, E Cloots, MS Simpson, N LeDuc, YV Serebrenik, H De Luca, ... Journal of Cell Biology 219 (2), 2020 | 49 | 2020 |
Evolution and function of the epithelial cell-specific ER stress sensor IRE1β E Cloots, MS Simpson, C De Nolf, WI Lencer, S Janssens, MJ Grey Mucosal immunology 14 (6), 1235-1246, 2021 | 21 | 2021 |
A quantitative single-cell flow cytometry assay for retrograde membrane trafficking using engineered cholera toxin MS Simpson, WI Lencer, P Luong Bio-protocol 10 (15), e3707-e3707, 2020 | 1 | 2020 |
IRE1α recognizes a structural motif in cholera toxin to activate an unfolded protein response MS Simpson, H De Luca, S Cauthorn, P Luong, ND Udeshi, T Svinkina, ... Journal of Cell Biology 223 (7), e202402062, 2024 | | 2024 |
Structural basis for recognition of unfolded proteins by the ER stress sensor ERN1/IRE1a M Simpson, H De Luca, S Cauthorn, P Luong, N Udeshi, T Svinkina, ... PROTEIN SCIENCE 32 (12), 2023 | | 2023 |
Structural basis for recognition of unfolded proteins by the ER stress sensor ERN1/IRE1α MS Simpson, H De Luca, S Cauthorn, P Luong, N Udeshi, T Svinkina, ... bioRxiv, 2023.06. 20.545791, 2023 | | 2023 |
Tu1524: A METASTABLE REGION OF THE CHOLERA TOXIN A1 SUBUNIT ACTIVATES THE ER STRESS SENSOR IRE1α TO AMPLIFY TOXICITY MS Simpson, MJ Grey, WI Lencer Gastroenterology 162 (7), S-997, 2022 | | 2022 |
Mo1133: CONFORMATIONAL DYNAMICS LINKING KINASE AND ENDONUCLEASE DOMAINS EXPLAIN THE DIVERGENT FUNCTION OF THE EPITHELIAL-SPECIFIC ER STRESS SENSOR IRE1β MJ Grey, D Jainchill, MS Simpson, WI Lencer Gastroenterology 162 (7), S-709, 2022 | | 2022 |
Conformational Dynamics Linking Kinase and Endonuclease Domains Explain the Divergent Function of IRE1 Paralogues MJ Grey, D Jainchill, MS Simpson, WI Lencer The FASEB Journal 36, 2022 | | 2022 |