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Mariska S Simpson
Mariska S Simpson
Boston Children's Hospital, Harvard University
Verified email at childrens.harvard.edu
Title
Cited by
Cited by
Year
IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress
MJ Grey, E Cloots, MS Simpson, N LeDuc, YV Serebrenik, H De Luca, ...
Journal of Cell Biology 219 (2), 2020
492020
Evolution and function of the epithelial cell-specific ER stress sensor IRE1β
E Cloots, MS Simpson, C De Nolf, WI Lencer, S Janssens, MJ Grey
Mucosal immunology 14 (6), 1235-1246, 2021
212021
A quantitative single-cell flow cytometry assay for retrograde membrane trafficking using engineered cholera toxin
MS Simpson, WI Lencer, P Luong
Bio-protocol 10 (15), e3707-e3707, 2020
12020
IRE1α recognizes a structural motif in cholera toxin to activate an unfolded protein response
MS Simpson, H De Luca, S Cauthorn, P Luong, ND Udeshi, T Svinkina, ...
Journal of Cell Biology 223 (7), e202402062, 2024
2024
Structural basis for recognition of unfolded proteins by the ER stress sensor ERN1/IRE1a
M Simpson, H De Luca, S Cauthorn, P Luong, N Udeshi, T Svinkina, ...
PROTEIN SCIENCE 32 (12), 2023
2023
Structural basis for recognition of unfolded proteins by the ER stress sensor ERN1/IRE1α
MS Simpson, H De Luca, S Cauthorn, P Luong, N Udeshi, T Svinkina, ...
bioRxiv, 2023.06. 20.545791, 2023
2023
Tu1524: A METASTABLE REGION OF THE CHOLERA TOXIN A1 SUBUNIT ACTIVATES THE ER STRESS SENSOR IRE1α TO AMPLIFY TOXICITY
MS Simpson, MJ Grey, WI Lencer
Gastroenterology 162 (7), S-997, 2022
2022
Mo1133: CONFORMATIONAL DYNAMICS LINKING KINASE AND ENDONUCLEASE DOMAINS EXPLAIN THE DIVERGENT FUNCTION OF THE EPITHELIAL-SPECIFIC ER STRESS SENSOR IRE1β
MJ Grey, D Jainchill, MS Simpson, WI Lencer
Gastroenterology 162 (7), S-709, 2022
2022
Conformational Dynamics Linking Kinase and Endonuclease Domains Explain the Divergent Function of IRE1 Paralogues
MJ Grey, D Jainchill, MS Simpson, WI Lencer
The FASEB Journal 36, 2022
2022
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Articles 1–9