| Oral captopril versus placebo among 13 634 patients with suspected acute myocardial infarction: interim report from the Chinese Cardiac Study (CCS-1) Chinese Cardiac Study Collaborative Group The Lancet 345 (8951), 686-687, 1995 | 308 | 1995 |
| Ginseng polysaccharides alter the gut microbiota and kynurenine/tryptophan ratio, potentiating the antitumour effect of antiprogrammed cell death 1/programmed cell death ligand … J Huang, D Liu, Y Wang, L Liu, J Li, J Yuan, Z Jiang, Z Jiang, WLW Hsiao, ... Gut 71 (4), 734-745, 2022 | 213 | 2022 |
| miR-508-5p regulates multidrug resistance of gastric cancer by targeting ABCB1 and ZNRD1 Y Shang, Z Zhang, Z Liu, B Feng, G Ren, K Li, L Zhou, Y Sun, M Li, J Zhou, ... Oncogene 33 (25), 3267-3276, 2014 | 196 | 2014 |
| Effect of geniposide, a hypoglycemic glucoside, on hepatic regulating enzymes in diabetic mice induced by a high-fat diet and streptozotocin S Wu, G Wang, Z Liu, J Rao, L Lü, W Xu, S Wu, J Zhang Acta Pharmacologica Sinica 30 (2), 202-208, 2009 | 193 | 2009 |
| Natural polyphenol disposition via coupled metabolic pathways Z Liu, M Hu Expert opinion on drug metabolism & toxicology 3 (3), 389-406, 2007 | 161 | 2007 |
| Activation of Nrf2/HO-1 pathway by nardochinoid C inhibits inflammation and oxidative stress in lipopolysaccharide-stimulated macrophages JF Luo, XY Shen, CK Lio, Y Dai, CS Cheng, JX Liu, YD Yao, Y Yu, Y Xie, ... Frontiers in pharmacology 9, 911, 2018 | 145 | 2018 |
| Poor oral bioavailability of a promising anticancer agent andrographolide is due to extensive metabolism and efflux by P‐glycoprotein L Ye, T Wang, L Tang, W Liu, Z Yang, J Zhou, Z Zheng, Z Cai, M Hu, Z Liu Journal of pharmaceutical sciences 100 (11), 5007-5017, 2011 | 145 | 2011 |
| Mechanisms responsible for poor oral bioavailability of paeoniflorin: Role of intestinal disposition and interactions with sinomenine ZQ Liu, ZH Jiang, L Liu, M Hu Pharmaceutical research 23, 2768-2780, 2006 | 126 | 2006 |
| The effects of sinomenine on intestinal absorption of paeoniflorin by the everted rat gut sac model K Chan, ZQ Liu, ZH Jiang, H Zhou, YF Wong, HX Xu, L Liu Journal of ethnopharmacology 103 (3), 425-432, 2006 | 126 | 2006 |
| Effect of astragaloside IV on hepatic glucose‐regulating enzymes in diabetic mice induced by a high‐fat diet and streptozotocin L Lv, SY Wu, GF Wang, JJ Zhang, JX Pang, ZQ Liu, W Xu, SG Wu, JJ Rao Phytotherapy Research: An International Journal Devoted to Pharmacological …, 2010 | 122 | 2010 |
| Structure and concentration changes affect characterization of UGT isoform-specific metabolism of isoflavones L Tang, R Singh, Z Liu, M Hu Molecular pharmaceutics 6 (5), 1466-1482, 2009 | 117 | 2009 |
| A single bacterium restores the microbiome dysbiosis to protect bones from destruction in a rat model of rheumatoid arthritis H Pan, R Guo, Y Ju, Q Wang, J Zhu, Y Xie, Y Zheng, T Li, Z Liu, L Lu, F Li, ... Microbiome 7, 1-11, 2019 | 116 | 2019 |
| Histone methyltransferase KMT2D sustains prostate carcinogenesis and metastasis via epigenetically activating LIFR and KLF4 S Lv, L Ji, B Chen, S Liu, C Lei, X Liu, X Qi, Y Wang, E Lai-Han Leung, ... Oncogene 37 (10), 1354-1368, 2018 | 116 | 2018 |
| A Systematic Review of Phytochemistry, Pharmacology and Pharmacokinetics on Astragali Radix: Implications for Astragali Radix as a Personalized Medicine Z Guo, Y Lou, M Kong, Q Luo, Z Liu, J Wu International journal of molecular sciences 20 (6), 1463, 2019 | 114 | 2019 |
| Nanocarriers: a general strategy for enhancement of oral bioavailability of poorly absorbed or pre-systemically metabolized drugs Z Cai, Y Wang, LJ Zhu, ZQ Liu Current Drug Metabolism 11 (2), 197-207, 2010 | 114 | 2010 |
| Glucuronidation: driving factors and their impact on glucuronide disposition G Yang, S Ge, R Singh, S Basu, K Shatzer, M Zen, J Liu, Y Tu, C Zhang, ... Drug metabolism reviews 49 (2), 105-138, 2017 | 113 | 2017 |
| Artemisinin and its derivatives can significantly inhibit lung tumorigenesis and tumor metastasis through Wnt/β-catenin signaling Y Tong, Y Liu, H Zheng, L Zheng, W Liu, J Wu, R Ou, G Zhang, F Li, M Hu, ... Oncotarget 7 (21), 31413, 2016 | 112 | 2016 |
| The potentiated checkpoint blockade immunotherapy by ROS-responsive nanocarrier-mediated cascade chemo-photodynamic therapy L Hu, Z Cao, L Ma, Z Liu, G Liao, J Wang, S Shen, D Li, X Yang Biomaterials 223, 119469, 2019 | 107 | 2019 |
| Involvement of CYP3A4/5 and CYP2D6 in the metabolism of aconitine using human liver microsomes and recombinant CYP450 enzymes L Tang, L Ye, C Lv, Z Zheng, Y Gong, Z Liu Toxicology Letters 202 (1), 47-54, 2011 | 104 | 2011 |
| Influence of co-administrated sinomenine on pharmacokinetic fate of paeoniflorin in unrestrained conscious rats ZQ Liu, H Zhou, L Liu, ZH Jiang, YF Wong, Y Xie, X Cai, HX Xu, K Chan Journal of ethnopharmacology 99 (1), 61-67, 2005 | 104 | 2005 |
