Scleroderma renal crisis: patient characteristics and long-term outcomes H Penn, AJ Howie, EJ Kingdon, CC Bunn, RJ Stratton, CM Black, A Burns, ... QJM: An International Journal of Medicine 100 (8), 485-494, 2007 | 490 | 2007 |
Iloprost suppresses connective tissue growth factor production in fibroblasts and in the skin of scleroderma patients R Stratton, X Shiwen, G Martini, A Holmes, A Leask, T Haberberger, ... The Journal of clinical investigation 108 (2), 241-250, 2001 | 276 | 2001 |
The value of SPECT scans in identifying back pain likely to benefit from facet joint injection AL Dolan, PJ Ryan, NK Arden, R Stratton, JR Wedley, W Hamann, ... Rheumatology 35 (12), 1269-1273, 1996 | 217 | 1996 |
CCN2 is necessary for adhesive responses to transforming growth factor-β1 in embryonic fibroblasts X Shi-wen, LA Stanton, L Kennedy, D Pala, Y Chen, SL Howat, ... Journal of Biological Chemistry 281 (16), 10715-10726, 2006 | 210 | 2006 |
Prostacyclin derivatives prevent the fibrotic response to TGFβ2 by inhibiting the Ras/MEK/ERK pathway R Stratton, V Rajkumar, M Ponticos, B Nichols, X Shiwen, CM Black, ... The FASEB journal 16 (14), 1949-1951, 2002 | 184 | 2002 |
Pilot study of anti‐thymocyte globulin plus mycophenolate mofetil in recent‐onset diffuse scleroderma RJ Stratton, H Wilson, CM Black Rheumatology 40 (1), 84-88, 2001 | 183 | 2001 |
Epithelial cells promote fibroblast activation via IL-1α in systemic sclerosis N Aden, A Nuttall, X Shiwen, P De Winter, A Leask, CM Black, CP Denton, ... Journal of Investigative Dermatology 130 (9), 2191-2200, 2010 | 147 | 2010 |
N-terminal connective tissue growth factor is a marker of the fibrotic phenotype in scleroderma M Dziadzio, W Usinger, A Leask, D Abraham, CM Black, C Denton, ... Qjm 98 (7), 485-492, 2005 | 143 | 2005 |
Long-term low molecular weight heparin therapy for severe Raynaud's phenomenon: a pilot study CP Denton, K Howell, RJ Stratton, CM Black Clinical and experimental rheumatology 18 (4), 499-502, 2000 | 109 | 2000 |
Proteomic analysis of scleroderma lesional skin reveals activated wound healing phenotype of epidermal cell layer N Aden, X Shiwen, D Aden, C Black, A Nuttall, CP Denton, A Leask, ... Rheumatology 47 (12), 1754-1760, 2008 | 93 | 2008 |
A role of myocardin related transcription factor-A (MRTF-A) in scleroderma related fibrosis X Shiwen, R Stratton, J Nikitorowicz-Buniak, B Ahmed-Abdi, M Ponticos, ... PloS one 10 (5), e0126015, 2015 | 92 | 2015 |
Partially evoked epithelial-mesenchymal transition (EMT) is associated with increased TGFβ signaling within lesional scleroderma skin J Nikitorowicz-Buniak, CP Denton, D Abraham, R Stratton PLoS One 10 (7), e0134092, 2015 | 82 | 2015 |
Abnormally differentiating keratinocytes in the epidermis of systemic sclerosis patients show enhanced secretion of CCN2 and S100A9 J Nikitorowicz-Buniak, X Shiwen, CP Denton, D Abraham, R Stratton Journal of Investigative Dermatology 134 (11), 2693-2702, 2014 | 80 | 2014 |
Rosiglitazone alleviates the persistent fibrotic phenotype of lesional skin scleroderma fibroblasts X Shi-wen, M Eastwood, RJ Stratton, CP Denton, A Leask, DJ Abraham Rheumatology 49 (2), 259-263, 2010 | 77 | 2010 |
Different patterns of endothelial cell activation in renal and pulmonary vascular disease in scleroderma. RJ Stratton, JG Coghlan, JD Pearson, A Burns, P Sweny, DJ Abraham, ... QJM: monthly journal of the Association of Physicians 91 (8), 561-566, 1998 | 65 | 1998 |
Autoimmunity and HIV R Stratton, G Slapak, T Mahungu, S Kinloch-de Loes Current opinion in infectious diseases 22 (1), 49-56, 2009 | 57 | 2009 |
The plasma biomarker soluble SIGLEC-1 is associated with the type I interferon transcriptional signature, ethnic background and renal disease in systemic lupus erythematosus JJ Oliveira, S Karrar, DB Rainbow, CL Pinder, P Clarke, AR García, ... Arthritis research & therapy 20 (1), 1-13, 2018 | 44 | 2018 |
Metabolic reprogramming of glycolysis and glutamine metabolism are key events in myofibroblast transition in systemic sclerosis pathogenesis J Henderson, L Duffy, R Stratton, D Ford, S O’Reilly Journal of Cellular and Molecular Medicine 24 (23), 14026-14038, 2020 | 43 | 2020 |
Antioxidants and NOX1/NOX4 inhibition blocks TGFβ1-induced CCN2 and α-SMA expression in dermal and gingival fibroblasts H Murphy-Marshman, K Quensel, X Shi-Wen, R Barnfield, J Kelly, A Peidl, ... PLoS One 12 (10), e0186740, 2017 | 41 | 2017 |
Interleukin-31 promotes pathogenic mechanisms underlying skin and lung fibrosis in scleroderma B Yaseen, H Lopez, Z Taki, S Zafar, H Rosario, BA Abdi, S Vigneswaran, ... Rheumatology 59 (9), 2625-2636, 2020 | 36 | 2020 |