Metabolic flexibility determines human NK cell functional fate in the tumor microenvironment SM Poznanski, K Singh, TM Ritchie, JA Aguiar, IY Fan, AL Portillo, ... Cell Metabolism 33 (6), 1205-1220. e5, 2021 | 137 | 2021 |
What defines NK cell functional fate: phenotype or metabolism? SM Poznanski, AA Ashkar Frontiers in immunology 10, 465987, 2019 | 108 | 2019 |
M2-polarized and tumor-associated macrophages alter NK cell phenotype and function in a contact-dependent manner T Krneta, A Gillgrass, S Poznanski, M Chew, AJ Lee, M Kolb, AA Ashkar Journal of Leucocyte Biology 101 (1), 285-295, 2017 | 94 | 2017 |
IL-18/IL-15/IL-12 synergy induces elevated and prolonged IFN-γ production by ex vivo expanded NK cells which is not due to enhanced STAT4 activation E Lusty, SM Poznanski, K Kwofie, TS Mandur, DA Lee, CD Richards, ... Molecular immunology 88, 138-147, 2017 | 78 | 2017 |
Immunometabolism of T cells and NK cells: metabolic control of effector and regulatory function SM Poznanski, NG Barra, AA Ashkar, JD Schertzer Inflammation research 67, 813-828, 2018 | 62 | 2018 |
Asthma exacerbations on benralizumab are largely non‐eosinophilic. SM Poznanski, M Mukherjee, N Zhao, C Huang, K Radford, AA Ashkar, ... Allergy 76 (1), 2021 | 49 | 2021 |
Ex vivo-expanded NK cells from blood and ascites of ovarian cancer patients are cytotoxic against autologous primary ovarian cancer cells T Nham, SM Poznanski, IY Fan, MM Shenouda, MV Chew, AJ Lee, ... Cancer Immunology, Immunotherapy 67, 575-587, 2018 | 43 | 2018 |
Expanded CD56superbrightCD16+ NK Cells from Ovarian Cancer Patients Are Cytotoxic against Autologous Tumor in a Patient-Derived Xenograft Murine Model SM Poznanski, T Nham, MV Chew, AJ Lee, JA Hammill, IY Fan, M Butcher, ... Cancer immunology research 6 (10), 1174-1185, 2018 | 42 | 2018 |
Aging and interferons: impacts on inflammation and viral disease outcomes E Feng, E Balint, SM Poznanski, AA Ashkar, M Loeb Cells 10 (3), 708, 2021 | 41 | 2021 |
Ex vivo-expanded natural killer cells derived from long-term cryopreserved cord blood are cytotoxic against primary breast cancer cells T Nham, SM Poznanski, IY Fan, F Vahedi, MM Shenouda, AJ Lee, ... Journal of Immunotherapy 41 (2), 64-72, 2018 | 40 | 2018 |
Combined stimulation with interleukin-18 and interleukin-12 potently induces interleukin-8 production by natural killer cells SM Poznanski, AJ Lee, T Nham, E Lusty, MJ Larché, DA Lee, AA Ashkar Journal of Innate Immunity 9 (5), 511-525, 2017 | 37 | 2017 |
Expanded human NK cells armed with CAR uncouple potent anti-tumor activity from off-tumor toxicity against solid tumors AL Portillo, R Hogg, SM Poznanski, EA Rojas, NJ Cashell, JA Hammill, ... Iscience 24 (6), 2021 | 35 | 2021 |
Shining light on the significance of NK cell CD56 brightness SM Poznanski, AA Ashkar Cellular & molecular immunology 15 (12), 1071-1073, 2018 | 29 | 2018 |
Type I interferon receptor on NK cells negatively regulates interferon-γ production AJ Lee, F Mian, SM Poznanski, M Stackaruk, T Chan, MV Chew, ... Frontiers in immunology 10, 1261, 2019 | 26 | 2019 |
Ex Vivo Expanded Human NK Cells Survive and Proliferate in Humanized Mice with Autologous Human Immune Cells F Vahedi, T Nham, SM Poznanski, MV Chew, MM Shenouda, D Lee, ... Scientific reports 7 (1), 12083, 2017 | 24 | 2017 |
Expanded human NK cells from lung cancer patients sensitize patients’ PDL1− negative tumors to PD1-blockade therapy SM Poznanski, TM Ritchie, IY Fan, A El-Sayes, AL Portillo, R Ben-Avi, ... Journal for immunotherapy of cancer 9 (1), 2021 | 23 | 2021 |
Type I interferon signalling is not required for the induction of endotoxin tolerance Y Karimi, SM Poznanski, F Vahedi, B Chen, MV Chew, AJ Lee, AA Ashkar Cytokine 95, 7-11, 2017 | 13 | 2017 |
Type I interferon regulates proteolysis by macrophages to prevent immunopathology following viral infection AJ Lee, E Feng, MV Chew, E Balint, SM Poznanski, E Giles, A Zhang, ... PLoS Pathogens 18 (5), e1010471, 2022 | 7 | 2022 |
Benralizumab's anti-eosinophil efficacy may be decreased by impaired NK cell activity SM Poznanski, A Portillo, M Mukherjee, A Bhalla, K Son, AA Ashkar, ... European Respiratory Journal 59 (4), 2022 | 3 | 2022 |
Recent advances in the use of NK cells against cancer AE Gillgrass, T Krneta, SM Poznanski, AA Ashkar Cancer Immunology: Bench to Bedside Immunotherapy of Cancers, 327-348, 2021 | 2 | 2021 |