Complement receptor 2/CD21− human naive B cells contain mostly autoreactive unresponsive clones I Isnardi, YS Ng, L Menard, G Meyers, D Saadoun, I Srdanovic, J Samuels, ... Blood, The Journal of the American Society of Hematology 115 (24), 5026-5036, 2010 | 487 | 2010 |
The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans L Menard, D Saadoun, I Isnardi, YS Ng, G Meyers, C Massad, C Price, ... The Journal of clinical investigation 121 (9), 2011 | 337 | 2011 |
IRAK-4-and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans I Isnardi, YS Ng, I Srdanovic, R Motaghedi, S Rudchenko, H von Bernuth, ... Immunity 29 (5), 746-757, 2008 | 264 | 2008 |
CD40 ligand and MHC class II expression are essential for human peripheral B cell tolerance M Hervé, I Isnardi, Y Ng, JB Bussel, HD Ochs, C Cunningham-Rundles, ... The Journal of experimental medicine 204 (7), 1583-1593, 2007 | 153 | 2007 |
Self-reactive VH4-34–expressing IgG B cells recognize commensal bacteria JN Schickel, S Glauzy, YS Ng, N Chamberlain, C Massad, I Isnardi, ... Journal of Experimental Medicine 214 (7), 1991-2003, 2017 | 79 | 2017 |
Two distinct tyrosine-based motifs enable the inhibitory receptor FcγRIIB to cooperatively recruit the inositol phosphatases SHIP1/2 and the adapters Grb2/Grap I Isnardi, R Lesourne, P Bruhns, WH Fridman, JC Cambier, M Daëron Journal of Biological Chemistry 279 (50), 51931-51938, 2004 | 70 | 2004 |
Linker for activation of T cells integrates positive and negative signaling in mast cells O Malbec, M Malissen, I Isnardi, R Lesourne, AM Mura, WH Fridman, ... The Journal of Immunology 173 (8), 5086-5094, 2004 | 61 | 2004 |
The SH2 domain-containing inositol 5-phosphatase SHIP1 is recruited to the intracytoplasmic domain of human FcγRIIB and is mandatory for negative regulation of B cell activation I Isnardi, P Bruhns, G Bismuth, WH Fridman, M Daëron Immunology letters 104 (1-2), 156-165, 2006 | 53 | 2006 |
Ex Vivo Analysis of Human Memory B Lymphocytes Specific for A and B Influenza Hemagglutinin by Polychromatic Flow-Cytometry M Bardelli, L Alleri, F Angiolini, F Buricchi, S Tavarini, C Sammicheli, ... PloS one 8 (8), e70620, 2013 | 17 | 2013 |
Impaired ATM activation in B cells is associated with bone resorption in rheumatoid arthritis KA Mensah, JW Chen, JN Schickel, I Isnardi, N Yamakawa, A Vega-Loza, ... Science translational medicine 11 (519), eaaw4626, 2019 | 16 | 2019 |
ANTIBODIES TARGETING CD32b AND METHODS OF USE THEREOF N Balke, T Calzascia, S Ewert, A Harris, HA Huet, I Isnardi, H Lu, ... US Patent App. 15/382,251, 2017 | 9 | 2017 |
Requirement of Mucosa‐Associated Lymphoid Tissue Lymphoma Translocation Protein 1 Protease Activity for Fcγ Receptor–Induced Arthritis, but Not Fcγ Receptor–Mediated Platelet … K Martin, R Touil, G Cvijetic, L Israel, Y Kolb, S Sarret, S Valeaux, ... Arthritis & Rheumatology 72 (6), 919-930, 2020 | 6 | 2020 |
Development of anti-CD32b antibodies with enhanced fc function for the treatment of B and plasma cell malignancies H Lu, RD Molony, D Chen, S Jang, B Wolf, S Ewert, M Flaherty, F Xu, ... Molecular cancer therapeutics 19 (10), 2089-2104, 2020 | 5 | 2020 |
MALT1 protease activity is required for FcgammaR-induced arthritis but not FcgammaR-mediated platelet elimination in mice K Martin, R Touil, G Cvijetic, L Israel, Y Kolb, S Sarret, S Valeaux, ... Arthritis Rheumatol 10, 2020 | 4 | 2020 |
Correction: Self-reactive VH4-34–expressing IgG B cells recognize commensal bacteria JN Schickel, S Glauzy, YS Ng, N Chamberlain, C Massad, I Isnardi, ... The Journal of experimental medicine 214 (7), 2161, 2017 | 1 | 2017 |
Abstract C028: Discovery and characterization of next generation monoclonal antibodies targeting the inhibitory Fc gamma receptor CD32b for the treatment of B and plasma cell … H Lu, D Chen, S Jang, B Wolf, S Ewert, M Flaherty, F Xu, S Isim, Y Shim, ... Molecular Cancer Therapeutics 18 (12_Supplement), C028-C028, 2019 | | 2019 |
PTPN22 Risk Allele Interferes with the Removal of Developing Autoreactive B Cells in Humans D Saadoun, L Menard, I Isnardi, Y Ng, G Meyers, C Abraham, ... ARTHRITIS AND RHEUMATISM 63 (10), S684-S684, 2011 | | 2011 |
Slam-Associated Protein (SAP) Is Essential for The Establishment of Human B Cell Tolerance L Menard, I Isnardi, S Tangye, K Nichols, A Klion, ... CLINICAL IMMUNOLOGY 135 (2), 295-295, 2010 | | 2010 |
Bases moléculaires du recrutement de l'inositol-phosphatase SHIP1 par les RFcgammaIIB, des récepteurs inhibiteurs de l'activation des lymphocytes B I Isnardi Paris 6, 2004 | | 2004 |