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Isabelle Isnardi
Isabelle Isnardi
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Year
Complement receptor 2/CD21 human naive B cells contain mostly autoreactive unresponsive clones
I Isnardi, YS Ng, L Menard, G Meyers, D Saadoun, I Srdanovic, J Samuels, ...
Blood, The Journal of the American Society of Hematology 115 (24), 5026-5036, 2010
4872010
The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans
L Menard, D Saadoun, I Isnardi, YS Ng, G Meyers, C Massad, C Price, ...
The Journal of clinical investigation 121 (9), 2011
3372011
IRAK-4-and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans
I Isnardi, YS Ng, I Srdanovic, R Motaghedi, S Rudchenko, H von Bernuth, ...
Immunity 29 (5), 746-757, 2008
2642008
CD40 ligand and MHC class II expression are essential for human peripheral B cell tolerance
M Hervé, I Isnardi, Y Ng, JB Bussel, HD Ochs, C Cunningham-Rundles, ...
The Journal of experimental medicine 204 (7), 1583-1593, 2007
1532007
Self-reactive VH4-34–expressing IgG B cells recognize commensal bacteria
JN Schickel, S Glauzy, YS Ng, N Chamberlain, C Massad, I Isnardi, ...
Journal of Experimental Medicine 214 (7), 1991-2003, 2017
792017
Two distinct tyrosine-based motifs enable the inhibitory receptor FcγRIIB to cooperatively recruit the inositol phosphatases SHIP1/2 and the adapters Grb2/Grap
I Isnardi, R Lesourne, P Bruhns, WH Fridman, JC Cambier, M Daëron
Journal of Biological Chemistry 279 (50), 51931-51938, 2004
702004
Linker for activation of T cells integrates positive and negative signaling in mast cells
O Malbec, M Malissen, I Isnardi, R Lesourne, AM Mura, WH Fridman, ...
The Journal of Immunology 173 (8), 5086-5094, 2004
612004
The SH2 domain-containing inositol 5-phosphatase SHIP1 is recruited to the intracytoplasmic domain of human FcγRIIB and is mandatory for negative regulation of B cell activation
I Isnardi, P Bruhns, G Bismuth, WH Fridman, M Daëron
Immunology letters 104 (1-2), 156-165, 2006
532006
Ex Vivo Analysis of Human Memory B Lymphocytes Specific for A and B Influenza Hemagglutinin by Polychromatic Flow-Cytometry
M Bardelli, L Alleri, F Angiolini, F Buricchi, S Tavarini, C Sammicheli, ...
PloS one 8 (8), e70620, 2013
172013
Impaired ATM activation in B cells is associated with bone resorption in rheumatoid arthritis
KA Mensah, JW Chen, JN Schickel, I Isnardi, N Yamakawa, A Vega-Loza, ...
Science translational medicine 11 (519), eaaw4626, 2019
162019
ANTIBODIES TARGETING CD32b AND METHODS OF USE THEREOF
N Balke, T Calzascia, S Ewert, A Harris, HA Huet, I Isnardi, H Lu, ...
US Patent App. 15/382,251, 2017
92017
Requirement of Mucosa‐Associated Lymphoid Tissue Lymphoma Translocation Protein 1 Protease Activity for Fcγ Receptor–Induced Arthritis, but Not Fcγ Receptor–Mediated Platelet …
K Martin, R Touil, G Cvijetic, L Israel, Y Kolb, S Sarret, S Valeaux, ...
Arthritis & Rheumatology 72 (6), 919-930, 2020
62020
Development of anti-CD32b antibodies with enhanced fc function for the treatment of B and plasma cell malignancies
H Lu, RD Molony, D Chen, S Jang, B Wolf, S Ewert, M Flaherty, F Xu, ...
Molecular cancer therapeutics 19 (10), 2089-2104, 2020
52020
MALT1 protease activity is required for FcgammaR-induced arthritis but not FcgammaR-mediated platelet elimination in mice
K Martin, R Touil, G Cvijetic, L Israel, Y Kolb, S Sarret, S Valeaux, ...
Arthritis Rheumatol 10, 2020
42020
Correction: Self-reactive VH4-34–expressing IgG B cells recognize commensal bacteria
JN Schickel, S Glauzy, YS Ng, N Chamberlain, C Massad, I Isnardi, ...
The Journal of experimental medicine 214 (7), 2161, 2017
12017
Abstract C028: Discovery and characterization of next generation monoclonal antibodies targeting the inhibitory Fc gamma receptor CD32b for the treatment of B and plasma cell …
H Lu, D Chen, S Jang, B Wolf, S Ewert, M Flaherty, F Xu, S Isim, Y Shim, ...
Molecular Cancer Therapeutics 18 (12_Supplement), C028-C028, 2019
2019
PTPN22 Risk Allele Interferes with the Removal of Developing Autoreactive B Cells in Humans
D Saadoun, L Menard, I Isnardi, Y Ng, G Meyers, C Abraham, ...
ARTHRITIS AND RHEUMATISM 63 (10), S684-S684, 2011
2011
Slam-Associated Protein (SAP) Is Essential for The Establishment of Human B Cell Tolerance
L Menard, I Isnardi, S Tangye, K Nichols, A Klion, ...
CLINICAL IMMUNOLOGY 135 (2), 295-295, 2010
2010
Bases moléculaires du recrutement de l'inositol-phosphatase SHIP1 par les RFcgammaIIB, des récepteurs inhibiteurs de l'activation des lymphocytes B
I Isnardi
Paris 6, 2004
2004
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