| Senolytics improve physical function and increase lifespan in old age M Xu, T Pirtskhalava, JN Farr, BM Weigand, AK Palmer, MM Weivoda, ... Nature medicine 24 (8), 1246-1256, 2018 | 1693 | 2018 |
| Senolytics in idiopathic pulmonary fibrosis: results from a first-in-human, open-label, pilot study JN Justice, AM Nambiar, T Tchkonia, NK LeBrasseur, R Pascual, ... EBioMedicine 40, 554-563, 2019 | 874 | 2019 |
| Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease LTJ Hickson, LGPL Prata, SA Bobart, TK Evans, N Giorgadze, SK Hashmi, ... EBioMedicine 47, 446-456, 2019 | 838 | 2019 |
| Targeting senescent cells alleviates obesity‐induced metabolic dysfunction AK Palmer, M Xu, YI Zhu, T Pirtskhalava, MM Weivoda, CM Hachfeld, ... Aging cell 18 (3), e12950, 2019 | 463 | 2019 |
| Obesity-induced cellular senescence drives anxiety and impairs neurogenesis M Ogrodnik, YI Zhu, LGP Langhi, T Tchkonia, P Krüger, E Fielder, ... Cell metabolism 29 (5), 1061-1077. e8, 2019 | 419 | 2019 |
| Senescent cell clearance by the immune system: Emerging therapeutic opportunities LGPL Prata, IG Ovsyannikova, T Tchkonia, JL Kirkland Seminars in immunology 40, 101275, 2018 | 369 | 2018 |
| Aged‐senescent cells contribute to impaired heart regeneration FC Lewis‐McDougall, PJ Ruchaya, E Domenjo‐Vila, T Shin Teoh, L Prata, ... Aging cell 18 (3), e12931, 2019 | 260 | 2019 |
| Senolytics reduce coronavirus-related mortality in old mice CD Camell, MJ Yousefzadeh, Y Zhu, LGPL Prata, MA Huggins, M Pierson, ... Science 373 (6552), eabe4832, 2021 | 217 | 2021 |
| Lipid-laden cells differentially distributed in the aging brain are functionally active and correspond to distinct phenotypes MK Shimabukuro, LGP Langhi, I Cordeiro, JM Brito, CMC Batista, ... Scientific reports 6 (1), 23795, 2016 | 110 | 2016 |
| Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity L Wang, B Wang, NS Gasek, Y Zhou, RL Cohn, DE Martin, W Zuo, ... Cell metabolism 34 (1), 75-89. e8, 2022 | 101 | 2022 |
| Corrigendum to ‘Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease … LTJ Hickson, LGPL Prata, SA Bobart, TK Evans, N Giorgadze, SK Hashmi, ... EBioMedicine 52, 2020 | 97 | 2020 |
| SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3 U Tripathi, R Nchioua, LGPL Prata, Y Zhu, EOW Gerdes, N Giorgadze, ... Aging (albany NY) 13 (18), 21838, 2021 | 64 | 2021 |
| Senolytics dasatinib and quercetin in idiopathic pulmonary fibrosis: results of a phase I, single-blind, single-center, randomized, placebo-controlled pilot trial on … A Nambiar, D Kellogg, J Justice, M Goros, J Gelfond, R Pascual, ... EBioMedicine 90, 2023 | 46 | 2023 |
| Senolytics in idiopathic pulmonary fibrosis: results from a first-in-human, open-label, pilot study. EBioMedicine 40: 554–563 JN Justice, AM Nambiar, T Tchkonia, NK LeBrasseur, R Pascual, ... | 45 | 2019 |
| Interesterified fat or palm oil as substitutes for partially hydrogenated fat in maternal diet can predispose obesity in adult male offspring TPR Magri, FS Fernandes, AS Souza, LGP Langhi, T Barboza, V Misan, ... Clinical nutrition 34 (5), 904-910, 2015 | 39 | 2015 |
| Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans Y Zhu, LGPL Prata, EOW Gerdes, JME Netto, T Pirtskhalava, N Giorgadze, ... EBioMedicine 77, 2022 | 38 | 2022 |
| Senolytics in idiopathic pulmonary fibrosis: results from a first-in-human, open-label, pilot study. EBioMedicine. 2019; 40: 554–63 JN Justice, AM Nambiar, T Tchkonia, NK LeBrasseur, R Pascual, ... PubMed Abstract| Publisher Full Text| Free Full Text| F1000 Recommendation, 2020 | 32 | 2020 |
| Epigenetic and senescence markers indicate an accelerated ageing-like state in women with preeclamptic pregnancies S Suvakov, R Ghamrawi, H Cubro, H Tu, WM White, YSB Tobah, NM Milic, ... EBioMedicine 70, 2021 | 27 | 2021 |
| Lipid-laden multilocular cells in the aging thymus are phenotypically heterogeneous LGP Langhi, LR Andrade, MK Shimabukuro, W van Ewijk, DD Taub, ... PLoS One 10 (10), e0141516, 2015 | 13 | 2015 |
| A chronic wound model to investigate skin cellular senescence SP Wyles, P Dashti, T Pirtskhalava, B Tekin, C Inman, LS Gomez, ... Aging (Albany NY) 15 (8), 2852, 2023 | 4 | 2023 |
Mark P. MattsonJohns Hopkins University School of MedicineVerified email at jhmi.edu
