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Timothy E Long
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Is drug release necessary for antimicrobial activity of siderophore-drug conjugates? Syntheses and biological studies of the naturally occurring salmycin “Trojan Horse …
TA Wencewicz, U Möllmann, TE Long, MJ Miller
Biometals 22, 633-648, 2009
1612009
Trihydroxamate siderophore–fluoroquinolone conjugates are selective sideromycin antibiotics that target Staphylococcus aureus
TA Wencewicz, TE Long, U Möllmann, MJ Miller
Bioconjugate chemistry 24 (3), 473-486, 2013
1462013
A novel β-lactam antibiotic activates tumor cell apoptotic program by inducing DNA damage
DM Smith, A Kazi, L Smith, TE Long, B Heldreth, E Turos, QP Dou
Molecular pharmacology 61 (6), 1348-1358, 2002
1002002
Novel N-thiolated β-lactam antibiotics selectively induce apoptosis in human tumor and transformed, but not normal or nontransformed, cells
A Kazi, R Hill, TE Long, DJ Kuhn, E Turos, QP Dou
Biochemical pharmacology 67 (2), 365-374, 2004
882004
N-Thiolated β-Lactams: novel antibacterial agents for methicillin-Resistant Staphylococcus aureus
E Turos, TE Long, MI Konaklieva, C Coates, JY Shim, S Dickey, DV Lim, ...
Bioorganic & medicinal chemistry letters 12 (16), 2229-2231, 2002
74*2002
Repurposing thiram and disulfiram as antibacterial agents for multidrug-resistant Staphylococcus aureus infections
TE Long
Antimicrobial agents and chemotherapy 61 (9), 10.1128/aac. 00898-17, 2017
662017
Generation of a highly attenuated strain of Pseudomonas aeruginosa for commercial production of alginate
ME Valentine, BD Kirby, TR Withers, SL Johnson, TE Long, Y Hao, ...
Microbial Biotechnology 13 (1), 162-175, 2020
632020
N-thiolated β-lactams: Studies on the mode of action and identification of a primary cellular target in Staphylococcus aureus
KD Revell, B Heldreth, TE Long, S Jang, E Turos
Bioorganic & medicinal chemistry 15 (6), 2453-2467, 2007
632007
N-Methylthio β-lactam antibacterials: Effects of the C3/C4 ring substituents on anti-MRSA activity
E Turos, C Coates, JY Shim, Y Wang, JM Leslie, TE Long, GSK Reddy, ...
Bioorganic & medicinal chemistry 13 (23), 6289-6308, 2005
582005
N-Thiolated β-lactam antibacterials: Effects of the N-organothio substituent on anti-MRSA activity
B Heldreth, TE Long, S Jang, GSK Reddy, E Turos, S Dickey, DV Lim
Bioorganic & medicinal chemistry 14 (11), 3775-3784, 2006
542006
Anti-tumor activity of N-thiolated β-lactam antibiotics
D Chen, SC Falsetti, M Frezza, V Milacic, A Kazi, QC Cui, TE Long, ...
Cancer letters 268 (1), 63-69, 2008
522008
N-Thiolated β-lactams: A new family of anti-Bacillus agents
E Turos, TE Long, B Heldreth, JM Leslie, GSK Reddy, Y Wang, C Coates, ...
Bioorganic & medicinal chemistry letters 16 (8), 2084-2090, 2006
512006
Disulfiram-based disulfides as narrow-spectrum antibacterial agents
JG Sheppard, KR Frazier, P Saralkar, MF Hossain, WJ Geldenhuys, ...
Bioorganic & medicinal chemistry letters 28 (8), 1298-1302, 2018
432018
N-Thiolated β-lactams
TE Long, E Turos
Current Medicinal Chemistry-Anti-Infective Agents 1 (3), 251-268, 2002
392002
Antibacterial activity of disulfiram and its metabolites
KR Frazier, JA Moore, TE Long
Journal of applied microbiology 126 (1), 79-86, 2019
382019
Allicin-inspired pyridyl disulfides as antimicrobial agents for multidrug-resistant Staphylococcus aureus
JG Sheppard, JP McAleer, P Saralkar, WJ Geldenhuys, TE Long
European journal of medicinal chemistry 143, 1185-1195, 2018
382018
Phosphonium lipocations as antiparasitic agents
TE Long, X Lu, M Galizzi, R Docampo, J Gut, PJ Rosenthal
Bioorganic & medicinal chemistry letters 22 (8), 2976-2979, 2012
362012
Lipase-catalyzed resolution of 4-aryl-substituted β-lactams: effect of substitution on the 4-aryl ring
JA Carr, TF Al-Azemi, TE Long, JY Shim, CM Coates, E Turos, KS Bisht
Tetrahedron 59 (46), 9147-9160, 2003
322003
1, 4-Naphthoquinone cations as antiplasmodial agents: hydroxy-, acyloxy-, and alkoxy-substituted analogues
X Lu, A Altharawi, J Gut, PJ Rosenthal, TE Long
ACS medicinal chemistry letters 3 (12), 1029-1033, 2012
302012
Effect of aryl ring fluorination on the antibacterial properties of C4 aryl-substituted N-methylthio β-Lactams
TE Long, E Turos, MI Konaklieva, AL Blum, A Amry, EA Baker, ...
Bioorganic & medicinal chemistry 11 (8), 1859-1863, 2003
272003
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