Is drug release necessary for antimicrobial activity of siderophore-drug conjugates? Syntheses and biological studies of the naturally occurring salmycin “Trojan Horse … TA Wencewicz, U Möllmann, TE Long, MJ Miller Biometals 22, 633-648, 2009 | 161 | 2009 |
Trihydroxamate siderophore–fluoroquinolone conjugates are selective sideromycin antibiotics that target Staphylococcus aureus TA Wencewicz, TE Long, U Möllmann, MJ Miller Bioconjugate chemistry 24 (3), 473-486, 2013 | 146 | 2013 |
A novel β-lactam antibiotic activates tumor cell apoptotic program by inducing DNA damage DM Smith, A Kazi, L Smith, TE Long, B Heldreth, E Turos, QP Dou Molecular pharmacology 61 (6), 1348-1358, 2002 | 100 | 2002 |
Novel N-thiolated β-lactam antibiotics selectively induce apoptosis in human tumor and transformed, but not normal or nontransformed, cells A Kazi, R Hill, TE Long, DJ Kuhn, E Turos, QP Dou Biochemical pharmacology 67 (2), 365-374, 2004 | 88 | 2004 |
N-Thiolated β-Lactams: novel antibacterial agents for methicillin-Resistant Staphylococcus aureus E Turos, TE Long, MI Konaklieva, C Coates, JY Shim, S Dickey, DV Lim, ... Bioorganic & medicinal chemistry letters 12 (16), 2229-2231, 2002 | 74* | 2002 |
Repurposing thiram and disulfiram as antibacterial agents for multidrug-resistant Staphylococcus aureus infections TE Long Antimicrobial agents and chemotherapy 61 (9), 10.1128/aac. 00898-17, 2017 | 66 | 2017 |
Generation of a highly attenuated strain of Pseudomonas aeruginosa for commercial production of alginate ME Valentine, BD Kirby, TR Withers, SL Johnson, TE Long, Y Hao, ... Microbial Biotechnology 13 (1), 162-175, 2020 | 63 | 2020 |
N-thiolated β-lactams: Studies on the mode of action and identification of a primary cellular target in Staphylococcus aureus KD Revell, B Heldreth, TE Long, S Jang, E Turos Bioorganic & medicinal chemistry 15 (6), 2453-2467, 2007 | 63 | 2007 |
N-Methylthio β-lactam antibacterials: Effects of the C3/C4 ring substituents on anti-MRSA activity E Turos, C Coates, JY Shim, Y Wang, JM Leslie, TE Long, GSK Reddy, ... Bioorganic & medicinal chemistry 13 (23), 6289-6308, 2005 | 58 | 2005 |
N-Thiolated β-lactam antibacterials: Effects of the N-organothio substituent on anti-MRSA activity B Heldreth, TE Long, S Jang, GSK Reddy, E Turos, S Dickey, DV Lim Bioorganic & medicinal chemistry 14 (11), 3775-3784, 2006 | 54 | 2006 |
Anti-tumor activity of N-thiolated β-lactam antibiotics D Chen, SC Falsetti, M Frezza, V Milacic, A Kazi, QC Cui, TE Long, ... Cancer letters 268 (1), 63-69, 2008 | 52 | 2008 |
N-Thiolated β-lactams: A new family of anti-Bacillus agents E Turos, TE Long, B Heldreth, JM Leslie, GSK Reddy, Y Wang, C Coates, ... Bioorganic & medicinal chemistry letters 16 (8), 2084-2090, 2006 | 51 | 2006 |
Disulfiram-based disulfides as narrow-spectrum antibacterial agents JG Sheppard, KR Frazier, P Saralkar, MF Hossain, WJ Geldenhuys, ... Bioorganic & medicinal chemistry letters 28 (8), 1298-1302, 2018 | 43 | 2018 |
N-Thiolated β-lactams TE Long, E Turos Current Medicinal Chemistry-Anti-Infective Agents 1 (3), 251-268, 2002 | 39 | 2002 |
Antibacterial activity of disulfiram and its metabolites KR Frazier, JA Moore, TE Long Journal of applied microbiology 126 (1), 79-86, 2019 | 38 | 2019 |
Allicin-inspired pyridyl disulfides as antimicrobial agents for multidrug-resistant Staphylococcus aureus JG Sheppard, JP McAleer, P Saralkar, WJ Geldenhuys, TE Long European journal of medicinal chemistry 143, 1185-1195, 2018 | 38 | 2018 |
Phosphonium lipocations as antiparasitic agents TE Long, X Lu, M Galizzi, R Docampo, J Gut, PJ Rosenthal Bioorganic & medicinal chemistry letters 22 (8), 2976-2979, 2012 | 36 | 2012 |
Lipase-catalyzed resolution of 4-aryl-substituted β-lactams: effect of substitution on the 4-aryl ring JA Carr, TF Al-Azemi, TE Long, JY Shim, CM Coates, E Turos, KS Bisht Tetrahedron 59 (46), 9147-9160, 2003 | 32 | 2003 |
1, 4-Naphthoquinone cations as antiplasmodial agents: hydroxy-, acyloxy-, and alkoxy-substituted analogues X Lu, A Altharawi, J Gut, PJ Rosenthal, TE Long ACS medicinal chemistry letters 3 (12), 1029-1033, 2012 | 30 | 2012 |
Effect of aryl ring fluorination on the antibacterial properties of C4 aryl-substituted N-methylthio β-Lactams TE Long, E Turos, MI Konaklieva, AL Blum, A Amry, EA Baker, ... Bioorganic & medicinal chemistry 11 (8), 1859-1863, 2003 | 27 | 2003 |