Multiplex CRISPR/Cas9 genome editing in hematopoietic stem cells for fetal hemoglobin reinduction generates chromosomal translocations C Samuelson, S Radtke, H Zhu, M Llewellyn, E Fields, S Cook, ... Molecular Therapy-Methods & Clinical Development 23, 507-523, 2021 | 27 | 2021 |
Efficient long-term multilineage engraftment of CD33-edited hematopoietic stem/progenitor cells in nonhuman primates NE Petty, S Radtke, E Fields, O Humbert, MJ Llewellyn, GS Laszlo, H Zhu, ... Molecular Therapy Methods & Clinical Development 31, 2023 | 1 | 2023 |
Multiplex Base Editing to Protect from CD33-Directed Therapy: Implications for Immune and Gene Therapy F Borot, O Humbert, GA Newby, E Fields, S Kohli, S Radtke, GS Laszlo, ... bioRxiv, 2023.02. 23.529353, 2023 | 1 | 2023 |
Efficient and Stable Makassar Base Editing in Nonhuman Primates S Radtke, E Fields, GA Newby, JS Yen, M Weiss, O Humbert, D Pande, ... Blood 142, 484, 2023 | | 2023 |
Multiplex Base Editing of Hematopoietic Stem and Progenitor Cells to Enrich Therapeutic Cells Post Engraftment O Humbert, ES Fields, MJ Llewellyn, SM Cook, GA Newby, J Yen, ... MOLECULAR THERAPY 29 (4), 40-41, 2021 | | 2021 |
Multiplex CRISPR/Cas9 Genome Editing Targeting the BCL11A/HBG Axis Maximizes Fetal Hemoglobin Reinduction but Generates Chromosomal Translocations Which Persist In Vivo C Samuelson, O Humbert, S Radtke, H Zhu, MJ Llewellyn, E Fields, ... Blood 136, 47-48, 2020 | | 2020 |
Base Editor-Mediated CD33 Engineering in Hematopoietic Stem and Progenitor Cells to Improve CD33-Targeted Cancer Therapies O Humbert, MJ Llewellyn, ES Fields, G Laszlo, BP Kleinstiver, RB Walter, ... MOLECULAR THERAPY 28 (4), 151-151, 2020 | | 2020 |