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Shaun Egolf
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Year
Acetyl-CoA metabolism supports multistep pancreatic tumorigenesis
A Carrer, S Trefely, S Zhao, SL Campbell, RJ Norgard, KC Schultz, ...
Cancer discovery 9 (3), 416-435, 2019
2212019
LSD1 inhibition promotes epithelial differentiation through derepression of fate-determining transcription factors
S Egolf, Y Aubert, M Doepner, A Anderson, A Maldonado-Lopez, ...
Cell reports 28 (8), 1981-1992. e7, 2019
592019
YAP1-mediated suppression of USP31 enhances NFκB activity to promote sarcomagenesis
S Ye, MA Lawlor, A Rivera-Reyes, S Egolf, S Chor, K Pak, GE Ciotti, ...
Cancer research 78 (10), 2705-2720, 2018
452018
MLL4 mediates differentiation and tumor suppression through ferroptosis
S Egolf, J Zou, A Anderson, CL Simpson, Y Aubert, S Prouty, K Ge, ...
Science Advances 7 (50), eabj9141, 2021
442021
YAP1 enhances NF-κB-dependent and independent effects on clock-mediated unfolded protein responses and autophagy in sarcoma
A Rivera-Reyes, S Ye, G E. Marino, S Egolf, G E. Ciotti, S Chor, Y Liu, ...
Cell death & disease 9 (11), 1108, 2018
382018
The unexpected noncatalytic roles of histone modifiers in development and disease
Y Aubert, S Egolf, BC Capell
Trends in Genetics 35 (9), 645-657, 2019
322019
LSD1: a viable therapeutic target in cutaneous squamous cell carcinoma?
S Egolf, BC Capell
Expert opinion on therapeutic targets 24 (7), 671-678, 2020
82020
Targeting SERCA2 in organotypic epidermis reveals MEK inhibition as a therapeutic strategy for Darier disease
SA Zaver, MK Sarkar, S Egolf, J Zou, A Tiwaa, BC Capell, JE Gudjonsson, ...
JCI insight 8 (18), 2023
22023
MLL4 is a critical mediator of differentiation and ferroptosis in the epidermis
S Egolf, J Zou, A Anderson, Y Aubert, K Ge, JT Seykora, BC Capell
bioRxiv, 2021.05. 03.442432, 2021
22021
1397 LSD1 is critical for epidermal development and skin barrier formation
N Kuprasertkul, S Egolf, C Magahis, C D'souza, J Zou, D Brennan-Crispi, ...
Journal of Investigative Dermatology 143 (5), S239, 2023
2023
321 A human tissue model of Darier disease reveals MEK as a novel therapeutic target downstream of SERCA2 deficiency
SA Zaver, M Sarkar, A Tiwaa, J Zou, S Egolf, B Capell, J Gudjonsson, ...
Journal of Investigative Dermatology 143 (5), S55, 2023
2023
788 Ferroptosis enhances epidermal cornification through transcriptional and metabolic reprogramming
N Kuprasertkul, C Magahis, S Egolf, CL Simpson, C Mesaros, KE Wellen, ...
Journal of Investigative Dermatology 143 (5), S135, 2023
2023
449 Investigating the role of ferroptosis in epidermal differentiation
N Kuprasertkul, S Egolf, J Zou, A Anderson, CL Simpson, K Ge, ...
Journal of Investigative Dermatology 142 (8), S76, 2022
2022
451 Modeling darier disease using gene-edited human keratinocytes and organotypic epidermis to identify therapeutic targets
CL Simpson, M Sarkar, S Egolf, J Zou, BC Capell, JE Gudjonsson
Journal of Investigative Dermatology 142 (8), S77, 2022
2022
The MLL4-LSD1 Epigenetic Axis Regulates Epidermal Differentiation and Ferroptosis: Implications for Skin Cancer and Disease
SA Egolf
University of Pennsylvania, 2022
2022
319 Epigenetic enhancer regulation in epithelial development and carcinogenesis
S Egolf, Y Aubert, A Anderson, Y Lan, A Maldonado-Lopez, C Simpson, ...
Journal of Investigative Dermatology 139 (5), S55, 2019
2019
Abstract B21: YAP1-mediated circadian oscillation in sarcoma
G Marino, S Egolf, S Ye, K Pak, J Shah, A Rivera-Reyes, S Chor, ...
Clinical Cancer Research 24 (2_Supplement), B21-B21, 2018
2018
Abstract B07: Regaining epigenetic control of the Hippo pathway to inhibit sarcomagenesis
S Ye, K Pak, J Shah, S Chor, S Egolf, G Marino, TSK Eisinger-Mathason
Clinical Cancer Research 24 (2_Supplement), B07-B07, 2018
2018
Regaining epigenetic control of the Hippo pathway to inhibit sarcomagenesis
S Ye, K Pak, J Shah, S Chor, S Egolf, G Marino, TS Eisinger-Mathason
CLINICAL CANCER RESEARCH 24 (2), 58-59, 2018
2018
YAP1-mediated circadian oscillation in sarcoma.
G Marino, S Egolf, S Ye, K Pak, J Shah, A Rivera-Reyes, S Chor, ...
CLINICAL CANCER RESEARCH 24 (2), 64-65, 2018
2018
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