Mitochondrial and cytoplasmic ROS have opposing effects on lifespan CE Schaar, DJ Dues, KK Spielbauer, E Machiela, JF Cooper, M Senchuk, ... PLoS genetics 11 (2), e1004972, 2015 | 207 | 2015 |
Modeling Parkinson’s Disease in C. elegans JF Cooper, JM Van Raamsdonk Journal of Parkinson's disease 8 (1), 17-32, 2018 | 148 | 2018 |
Activation of the mitochondrial unfolded protein response promotes longevity and dopamine neuron survival in Parkinson’s disease models JF Cooper, E Machiela, DJ Dues, KK Spielbauer, MM Senchuk, ... Scientific reports 7 (1), 16441, 2017 | 91 | 2017 |
Mitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways Z Wu, MM Senchuk, DJ Dues, BK Johnson, JF Cooper, L Lew, E Machiela, ... BMC biology 16, 1-19, 2018 | 89 | 2018 |
Delaying aging is neuroprotective in Parkinson’s disease: a genetic analysis in C. elegans models JF Cooper, DJ Dues, KK Speilbauer, E Machiela, MM Senchuck, ... npj Parkinson's Disease, 2015 | 83 | 2015 |
Novel animal model defines genetic contributions for neuron-to-neuron transfer of α-synuclein T Tyson, M Senchuk, JF Cooper, S George, JM Van Raamsdonk, ... Scientific Reports 7 (1), 7506, 2017 | 43 | 2017 |
Disruption of mitochondrial dynamics increases stress resistance through activation of multiple stress response pathways E Machiela, T Liontis, DJ Dues, PD Rudich, A Traa, L Wyman, C Kaufman, ... The FASEB Journal 34 (6), 8475, 2020 | 27 | 2020 |
α-synuclein expression from a single copy transgene increases sensitivity to stress and accelerates neuronal loss in genetic models of Parkinson's disease JF Cooper, KK Spielbauer, MM Senchuk, S Nadarajan, MP Colaiácovo, ... Experimental neurology 310, 58-69, 2018 | 25 | 2018 |
Stress increases in exopher-mediated neuronal extrusion require lipid biosynthesis, FGF, and EGF RAS/MAPK signaling JF Cooper, RJ Guasp, ML Arnold, BD Grant, M Driscoll Proceedings of the National Academy of Sciences 118 (36), e2101410118, 2021 | 22 | 2021 |
Quantitative approaches for scoring in vivo neuronal aggregate and organelle extrusion in large exopher vesicles in C. elegans ML Arnold, J Cooper, BD Grant, M Driscoll JoVE (Journal of Visualized Experiments), e61368, 2020 | 19 | 2020 |
Large vesicle extrusions from C. elegans neurons are consumed and stimulated by glial-like phagocytosis activity of the neighboring cell Y Wang, ML Arnold, AJ Smart, G Wang, RJ Androwski, A Morera, ... elife 12, e82227, 2023 | 13 | 2023 |
Modeling Parkinson’s disease in C. elegans. J Parkinsons Dis. 2018; 8 (1): 17–32 JF Cooper, JM Van Raamsdonk Epub 2018/02/27. doi: 10.3233/jpd-171258. PubMed PMID: 29480229, 0 | 6 | |
Intermediate filaments associate with aggresome-like structures in proteostressed C. elegans neurons and influence large vesicle extrusions as exophers ML Arnold, J Cooper, R Androwski, S Ardeshna, I Melentijevic, J Smart, ... Nature communications 14 (1), 4450, 2023 | 5 | 2023 |
Sulfur-Mediated Decarboxylative Coupling of 2-Nitrobenzyl Alcohols and Arylacetic Acids KX Nguyen, DK Nguyen, PH Pham, HV Le, TT Nguyen, NTS Phan Synlett 31 (11), 1112-1116, 2020 | 4 | 2020 |
Oocyte mitochondria link maternal environment to offspring phenotype N Burton, J Cooper, K Nguyen, D Gates, E Wolfram, C Capan, H Lee, ... | | 2024 |
Genetics: A cross-kingdom evolutionary handoff JF Cooper, X Wang, NO Burton Current Biology 32 (22), R1267-R1269, 2022 | | 2022 |
Modeling Parkinson's Disease in C. elegans (vol 8, pg 17, 2018) JF Cooper, JM Van Raamsdonk JOURNAL OF PARKINSONS DISEASE 10 (2), 745-745, 2020 | | 2020 |
Aging, Stress, and Pathogenesis of Parkinson's Disease: Studies Using C. elegans JF Cooper Van Andel Research Institute, 2018 | | 2018 |
Additional files for Z Wu, MM Senchuk, DJ Dues, BK Johnson, JF Cooper, L Lew, E Machiela, ... | | |
Large vesicle extrusion from C. elegans neurons requires phagocytic interaction via the ARF-6 and CED-1/DRAPER pathways Y Wang, ML Arnold, AJ Smart, G Wang, A Morera, KC Nguyen, ... | | |