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Zonghui Ma
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Year
Novel strategies targeting bromodomain-containing protein 4 (BRD4) for cancer drug discovery
D Liang, Y Yu, Z Ma
European journal of medicinal chemistry 200, 112426, 2020
482020
Specific non-genetic IAP-based protein erasers (SNIPERs) as a potential therapeutic strategy
Z Ma, Y Ji, Y Yu, D Liang
European journal of medicinal chemistry 216, 113247, 2021
312021
Discovery and development of selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors
B Li, K Yang, D Liang, C Jiang, Z Ma
European journal of medicinal chemistry 209, 112940, 2021
202021
Development of Novel Anticancer Agents with a Scaffold of Tetrahydropyrido[4,3-d]pyrimidine-2,4-dione
Z Ma, G Gao, K Fang, H Sun
ACS Medicinal Chemistry Letters 10 (2), 191-195, 2019
192019
Novel hydrazone moiety-bearing aminopyrimidines as selective inhibitors of epidermal growth factor receptor T790M mutant
M Qin, T Wang, B Xu, Z Ma, N Jiang, H Xie, P Gong, Y Zhao
European Journal of Medicinal Chemistry 104, 115-126, 2015
172015
Discovery of benzimidazole derivatives as potent and selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors with glucose consumption improving activity
Z Ma, L Jiang, B Li, D Liang, Y Feng, L Liu, C Jiang
Bioorganic & medicinal chemistry 46, 116352, 2021
112021
Synthesis and Anti‐Hepatitis B Virus Evaluation of 7‐Methoxy‐3‐heterocyclic quinolin‐6‐ols
Y Liu, G Feng, Z Ma, C Xu, Z Guo, P Gong, L Xu
Archiv der Pharmazie 348 (11), 776-785, 2015
72015
Bromodomain-containing protein 4 (BRD4): a key player in inflammatory bowel disease and potential to inspire epigenetic therapeutics
Z Ma, AA Bolinger, J Zhou, B Tian
Expert Opinion on Therapeutic Targets 27 (1), 1-7, 2023
62023
Design, synthesis of 1, 3-dimethylpyrimidine-2, 4-diones as potent and selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors with glucose consumption improving activity
Z Ma, L Jiang, G Li, D Liang, L Li, L Liu, C Jiang
Bioorganic Chemistry 101, 103971, 2020
62020
IDR-targeting compounds suppress HPV genome replication via disruption of phospho-BRD4 association with DNA damage response factors
SY Wu, HT Lai, NS Banerjee, Z Ma, JF Santana, S Wei, X Liu, M Zhang, ...
Molecular cell 84 (2), 202-220. e15, 2024
42024
Drug discovery targeting nuclear receptor binding SET domain protein 2 (NSD2)
Z Ma, AA Bolinger, H Chen, J Zhou
Journal of medicinal chemistry 66 (16), 10991-11026, 2023
42023
Synthesis of pyrido [4, 3–d] pyrimidine-2, 4 (1H, 3H)-diones and pyrido [4, 3–d] pyrimidine-2, 4, 5 (1H, 3H, 6H)-triones by oxidative aromatization
Z Ma, G Gao, H Sun
Tetrahedron Letters 67, 152847, 2021
32021
RIPTACs: A groundbreaking approach to drug discovery
Z Ma, AA Bolinger, J Zhou
Drug Discovery Today, 103774, 2023
22023
174 BRD4 AS A POTENTIAL THERAPEUTIC TARGET FOR CROHN'S DISEASEASSOCIATED FIBROSIS
C McAninch, M Chulkina, Z Ma, SB McAninch, RM Edwards, A Seideneck, ...
Gastroenterology 166 (5), S-40, 2024
2024
DEVELOPMENT OF NANOPARTICLE-ENCAPSULATED BRD4 INHIBITORS FOR NOVEL EPIGENETIC THERAPEUTICS OF IBD
M Shah, Z Ma, H Chen, Y Cong, J Zhou, E Rytting, B Tian
Inflammatory Bowel Diseases 29 (Supplement_1), S4-S4, 2023
2023
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