Peptide-based PET quantifies target engagement of PD-L1 therapeutics D Kumar, A Lisok, E Dahmane, M McCoy, S Shelake, S Chatterjee, V Allaj, ... The Journal of clinical investigation 129 (2), 616-630, 2019 | 111 | 2019 |
Curation of the pancreatic ductal adenocarcinoma subset of the cancer genome atlas is essential for accurate conclusions about survival-related molecular mechanisms I Peran, S Madhavan, SW Byers, MD McCoy Clinical Cancer Research 24 (16), 3813-3819, 2018 | 62 | 2018 |
Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice I Peran, S Dakshanamurthy, MD McCoy, A Mavropoulos, B Allo, ... Gastroenterology 160 (4), 1359-1372. e13, 2021 | 56 | 2021 |
Collaborative, Multidisciplinary Evaluation of Cancer Variants Through Virtual Molecular Tumor Boards Informs Local Clinical Practices S Rao, B Pitel, AH Wagner, SM Boca, M McCoy, I King, S Gupta, BH Park, ... JCO Clinical Cancer Informatics 4, 602-613, 2020 | 35 | 2020 |
Exploring approaches for predictive cancer patient digital twins: Opportunities for collaboration and innovation EA Stahlberg, M Abdel-Rahman, B Aguilar, A Asadpoure, RA Beckman, ... Frontiers in Digital Health 4, 1007784, 2022 | 30 | 2022 |
Inhibition of DNA repair pathways and induction of ROS are potential mechanisms of action of the small molecule inhibitor BOLD-100 in breast cancer S Bakewell, I Conde, Y Fallah, M McCoy, L Jin, AN Shajahan-Haq Cancers 12 (9), 2647, 2020 | 29 | 2020 |
Clingen cancer somatic working group–standardizing and democratizing access to cancer molecular diagnostic data to drive translational research S Madhavan, D Ritter, C Micheel, S Rao, A Roy, D Sonkin, M Mccoy, ... PACIFIC SYMPOSIUM ON BIOCOMPUTING 2018: Proceedings of the Pacific Symposium …, 2018 | 25 | 2018 |
The FDA-Approved Anthelmintic Pyrvinium Pamoate Inhibits Pancreatic Cancer Cells in Nutrient-Depleted Conditions by Targeting the Mitochondria CW Schultz, GA McCarthy, T Nerwal, A Nevler, JB DuHadaway, ... Molecular Cancer Therapeutics 20 (11), 2166-2176, 2021 | 24 | 2021 |
Envisioning the future of precision oncology trials S Madhavan, RA Beckman, MD McCoy, MJ Pishvaian, JR Brody, ... Nature Cancer, 1-3, 2020 | 22 | 2020 |
Predicting genetic variation severity using machine learning to interpret molecular simulations MD McCoy, J Hamre, DK Klimov, MS Jafri Biophysical journal 120 (2), 189-204, 2021 | 19 | 2021 |
Function and evolution of B-Raf loop dynamics relevant to cancer recurrence under drug inhibition GA Babbitt, ML Lynch, M McCoy, EP Fokoue, AO Hudson Journal of Biomolecular Structure and Dynamics 40 (1), 468-483, 2022 | 16 | 2022 |
De novo assembly and annotation of transcriptomes from two cultivars of Cannabis sativa with different cannabinoid profiles P McGarvey, J Huang, M McCoy, J Orvis, Y Katsir, N Lotringer, I Nesher, ... Gene 762, 145026, 2020 | 16 | 2020 |
Adapting crowdsourced clinical cancer curation in CIViC to the ClinGen minimum variant level data community‐driven standards AM Danos, DI Ritter, AH Wagner, K Krysiak, D Sonkin, C Micheel, ... Human Mutation 39 (11), 1721-1732, 2018 | 14 | 2018 |
Do Molecular Profiles of Primary Versus Metastatic Radioiodine Refractory Differentiated Thyroid Cancer Differ? CJ Gomes-Lima, L Shobab, D Wu, D Ylli, A Bikas, M McCoy, R Feldman, ... Frontiers in endocrinology 12, 623182, 2021 | 11 | 2021 |
SNP2SIM: a modular workflow for standardizing molecular simulation and functional analysis of protein variants MD McCoy, V Shivakumar, S Nimmagadda, MS Jafri, S Madhavan BMC bioinformatics 20, 1-8, 2019 | 10 | 2019 |
Machine learning-based prediction of drug and ligand binding in BCL-2 variants through molecular dynamics JR Hamre III, DK Klimov, MD McCoy, MS Jafri Computers in biology and medicine 140, 105060, 2022 | 9 | 2022 |
The RNA-binding protein HuR posttranscriptionally regulates the protumorigenic activator YAP1 in pancreatic ductal adenocarcinoma SZ Brown, GA McCarthy, JR Carroll, R Di Niro, C Pelz, A Jain, TL Sutton, ... Molecular and cellular biology, 2022 | 6 | 2022 |
A computational approach for prioritizing selection of therapies targeting drug resistant variation in anaplastic lymphoma kinase MD McCoy, S Madhavan AMIA Summits on Translational Science Proceedings 2018, 160, 2018 | 5 | 2018 |
HuR Plays a Role in Double-Strand Break Repair in Pancreatic Cancer Cells and Regulates Functional BRCA1-Associated-Ring-Domain-1 (BARD1) Isoforms A Jain, M McCoy, C Coats, SZ Brown, S Addya, C Pelz, RC Sears, CJ Yeo, ... Cancers 14 (7), 1848, 2022 | 4 | 2022 |
Translational Applications of Protein Structure Simulation: Predicting Phenotype of Missense Variants MD McCoy, S Madhavan, S Nimmagadda, D Klimov, MS Jafri Biophysical Journal 116 (3), 13a, 2019 | 3 | 2019 |