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Matthew Dean McCoy
Matthew Dean McCoy
Verified email at georgetown.edu
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Cited by
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Year
Peptide-based PET quantifies target engagement of PD-L1 therapeutics
D Kumar, A Lisok, E Dahmane, M McCoy, S Shelake, S Chatterjee, V Allaj, ...
The Journal of clinical investigation 129 (2), 616-630, 2019
1112019
Curation of the pancreatic ductal adenocarcinoma subset of the cancer genome atlas is essential for accurate conclusions about survival-related molecular mechanisms
I Peran, S Madhavan, SW Byers, MD McCoy
Clinical Cancer Research 24 (16), 3813-3819, 2018
622018
Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice
I Peran, S Dakshanamurthy, MD McCoy, A Mavropoulos, B Allo, ...
Gastroenterology 160 (4), 1359-1372. e13, 2021
562021
Collaborative, Multidisciplinary Evaluation of Cancer Variants Through Virtual Molecular Tumor Boards Informs Local Clinical Practices
S Rao, B Pitel, AH Wagner, SM Boca, M McCoy, I King, S Gupta, BH Park, ...
JCO Clinical Cancer Informatics 4, 602-613, 2020
352020
Exploring approaches for predictive cancer patient digital twins: Opportunities for collaboration and innovation
EA Stahlberg, M Abdel-Rahman, B Aguilar, A Asadpoure, RA Beckman, ...
Frontiers in Digital Health 4, 1007784, 2022
302022
Inhibition of DNA repair pathways and induction of ROS are potential mechanisms of action of the small molecule inhibitor BOLD-100 in breast cancer
S Bakewell, I Conde, Y Fallah, M McCoy, L Jin, AN Shajahan-Haq
Cancers 12 (9), 2647, 2020
292020
Clingen cancer somatic working group–standardizing and democratizing access to cancer molecular diagnostic data to drive translational research
S Madhavan, D Ritter, C Micheel, S Rao, A Roy, D Sonkin, M Mccoy, ...
PACIFIC SYMPOSIUM ON BIOCOMPUTING 2018: Proceedings of the Pacific Symposium …, 2018
252018
The FDA-Approved Anthelmintic Pyrvinium Pamoate Inhibits Pancreatic Cancer Cells in Nutrient-Depleted Conditions by Targeting the Mitochondria
CW Schultz, GA McCarthy, T Nerwal, A Nevler, JB DuHadaway, ...
Molecular Cancer Therapeutics 20 (11), 2166-2176, 2021
242021
Envisioning the future of precision oncology trials
S Madhavan, RA Beckman, MD McCoy, MJ Pishvaian, JR Brody, ...
Nature Cancer, 1-3, 2020
222020
Predicting genetic variation severity using machine learning to interpret molecular simulations
MD McCoy, J Hamre, DK Klimov, MS Jafri
Biophysical journal 120 (2), 189-204, 2021
192021
Function and evolution of B-Raf loop dynamics relevant to cancer recurrence under drug inhibition
GA Babbitt, ML Lynch, M McCoy, EP Fokoue, AO Hudson
Journal of Biomolecular Structure and Dynamics 40 (1), 468-483, 2022
162022
De novo assembly and annotation of transcriptomes from two cultivars of Cannabis sativa with different cannabinoid profiles
P McGarvey, J Huang, M McCoy, J Orvis, Y Katsir, N Lotringer, I Nesher, ...
Gene 762, 145026, 2020
162020
Adapting crowdsourced clinical cancer curation in CIViC to the ClinGen minimum variant level data community‐driven standards
AM Danos, DI Ritter, AH Wagner, K Krysiak, D Sonkin, C Micheel, ...
Human Mutation 39 (11), 1721-1732, 2018
142018
Do Molecular Profiles of Primary Versus Metastatic Radioiodine Refractory Differentiated Thyroid Cancer Differ?
CJ Gomes-Lima, L Shobab, D Wu, D Ylli, A Bikas, M McCoy, R Feldman, ...
Frontiers in endocrinology 12, 623182, 2021
112021
SNP2SIM: a modular workflow for standardizing molecular simulation and functional analysis of protein variants
MD McCoy, V Shivakumar, S Nimmagadda, MS Jafri, S Madhavan
BMC bioinformatics 20, 1-8, 2019
102019
Machine learning-based prediction of drug and ligand binding in BCL-2 variants through molecular dynamics
JR Hamre III, DK Klimov, MD McCoy, MS Jafri
Computers in biology and medicine 140, 105060, 2022
92022
The RNA-binding protein HuR posttranscriptionally regulates the protumorigenic activator YAP1 in pancreatic ductal adenocarcinoma
SZ Brown, GA McCarthy, JR Carroll, R Di Niro, C Pelz, A Jain, TL Sutton, ...
Molecular and cellular biology, 2022
62022
A computational approach for prioritizing selection of therapies targeting drug resistant variation in anaplastic lymphoma kinase
MD McCoy, S Madhavan
AMIA Summits on Translational Science Proceedings 2018, 160, 2018
52018
HuR Plays a Role in Double-Strand Break Repair in Pancreatic Cancer Cells and Regulates Functional BRCA1-Associated-Ring-Domain-1 (BARD1) Isoforms
A Jain, M McCoy, C Coats, SZ Brown, S Addya, C Pelz, RC Sears, CJ Yeo, ...
Cancers 14 (7), 1848, 2022
42022
Translational Applications of Protein Structure Simulation: Predicting Phenotype of Missense Variants
MD McCoy, S Madhavan, S Nimmagadda, D Klimov, MS Jafri
Biophysical Journal 116 (3), 13a, 2019
32019
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