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Jianzhong Chen
Jianzhong Chen
College of Medicine, University of Kentucky
Verified email at uky.edu
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Cited by
Year
The β3-adrenergic receptor agonist mirabegron improves glucose homeostasis in obese humans
BS Finlin, H Memetimin, B Zhu, AL Confides, HJ Vekaria, RH El Khouli, ...
The Journal of clinical investigation 130 (5), 2319-2331, 2020
2022020
The Unique Pharmacological Characteristics of Mifepristone (RU486): from Terminating Pregnancy to Preventing Cancer Metastasis
J Chen, J Wang, J Shao, Y Gao, J Xu, S Yu, Z Liu, L Jia
Medicinal Research Reviews 34 (5), 979-1000, 2014
902014
Dendrimeric anticancer prodrugs for targeted delivery of ursolic acid to folate receptor-expressing cancer cells: synthesis and biological evaluation
Y Gao, Z Li, X Xie, C Wang, J You, F Mo, B Jin, J Chen, J Shao, H Chen, ...
European journal of pharmaceutical sciences 70, 55-63, 2015
822015
A pentacyclic triterpene natural product, ursolic acid and its prodrug US597 inhibit targets within cell adhesion pathway and prevent cancer metastasis
L Xiang, T Chi, Q Tang, X Yang, M Ou, X Chen, X Yu, J Chen, RJY Ho, ...
Oncotarget 6 (11), 9295, 2015
792015
PLGA-PEG-PLGA triblock copolymeric micelles as oral drug delivery system: In vitro drug release and in vivo pharmacokinetics assessment
X Chen, J Chen, B Li, X Yang, R Zeng, Y Liu, T Li, RJY Ho, J Shao
Journal of colloid and interface science 490, 542-552, 2017
772017
Synergism of Ursolic Acid Derivative US597 with 2-deoxy-D-glucose to Preferentially Induce Tumor Cell Death by Dual-targeting of Apoptosis and Glycolysis
J Wang, Z Jiang, L Xiang, Y Li, M Ou, X Yang, J Shao, Y Lu, L Lin, J Chen, ...
Scientific reports 4, 2014
742014
Chitosan-based nanoparticles for improved anticancer efficacy and bioavailability of mifepristone
GLLJ Huijuan Zhang, Fuqiang Wu, Yazhen Li, Xiping Yang, Jiamei Huang ...
Beilstein J. Nanotechnol 7, 1861–1870., 2016
712016
Drug enterohepatic circulation and disposition: constituents of systems pharmacokinetics
Y Gao, J Shao, Z Jiang, J Chen, S Gu, S Yu, K Zheng, L Jia
Drug discovery today 19 (3), 326-340, 2014
652014
UP12, a novel ursolic acid derivative with potential for targeting multiple signaling pathways in hepatocellular carcinoma
H Dong, X Yang, J Xie, L Xiang, Y Li, M Ou, T Chi, Z Liu, S Yu, Y Gao, ...
Biochemical Pharmacology 93 (2), 151-162, 2015
552015
Synthesis, Spectral Characterization, and in Vitro Cellular Activities of Metapristone, a Potential Cancer Metastatic Chemopreventive Agent Derived from Mifepristone (RU486)
J Wang, J Chen, L Wan, J Shao, Y Lu, Y Zhu, M Ou, S Yu, H Chen, L Jia
The AAPS journal 16 (2), 289-298, 2014
532014
Structure-based discovery of mPGES-1 inhibitors suitable for preclinical testing in wild-type mice as a new generation of anti-inflammatory drugs
K Ding, Z Zhou, S Hou, Y Yuan, S Zhou, X Zheng, J Chen, C Loftin, ...
Scientific reports 8 (1), 5205, 2018
472018
Characterization of New Metabolites from in Vivo Biotransformation of Norisoboldine by Liquid Chromatography/Mass Spectrometry and NMR Spectroscopy
J Chen, G Chou, C Wang, L Yang, SWA Bligh, Z Wang
Journal of pharmaceutical and biomedical analysis 52 (5), 687-693, 2010
282010
Self-assembled chitosan/rose bengal derivative nanoparticles for targeted sonodynamic therapy: preparation and tumor accumulation
Y Gao, Z Li, C Wang, J You, B Jin, F Mo, J Chen, Y Zheng, H Chen
RSC Advances 5 (23), 17915-17923, 2015
242015
A novel UPLC/MS/MS method for rapid determination of metapristone in rat plasma, a new cancer metastasis chemopreventive agent derived from mifepristone (RU486)
JZ Chen, JC Wang, Y Gao, RJ Zeng, Z Jiang, YW Zhu, JW Shao, L Jia
Journal of pharmaceutical and biomedical analysis 95, 158-163, 2014
242014
The traditional Chinese medicine Achyranthes bidentata and our de novo conception of its metastatic chemoprevention: from phytochemistry to pharmacology
Z Jiang, J Qian, H Dong, J Yang, X Yu, J Chen, H Chen, Q Shi, L Jia
Scientific reports 7 (1), 3888, 2017
232017
Development of a sensitive and rapid UPLC‐MS/MS method for the determination of koumine in rat plasma: application to a pharmacokinetic study
JZ Chen, Y Li, JP Xiao, SS Wu, HW Song
Biomedical Chromatography 27 (6), 736-740, 2013
232013
Effects of dicyclohexyl phthalate exposure on PXR activation and lipid homeostasis in mice
Y Sui, Z Meng, J Chen, J Liu, R Hernandez, MB Gonzales, T Gwag, ...
Environmental health perspectives 129 (12), 127001, 2021
222021
Separation of ginseng active ingredients and their roles in cancer metastasis supplementary therapy
J Xie, J Shao, Y Lu, J Chen, J Wang, S Yu, L Jia
Current drug metabolism 14 (5), 616-623, 2013
222013
Short Chain Fatty Acids Taken at Time of Thrombectomy in Acute Ischemic Stroke Patients Are Independent of Stroke Severity But Associated With Inflammatory Markers and Worse …
N Henry, J Frank, C McLouth, AL Trout, A Morris, J Chen, AM Stowe, ...
Frontiers in Immunology 12, 2022
212022
Ultrasound/microwave‐assisted extraction and comparative analysis of bioactive/toxic indole alkaloids in different medicinal parts of Gelsemium elegans Benth by …
Y Li, RJ Zeng, Q Lu, SS Wu, JZ Chen
Journal of separation science 37 (3), 308-313, 2014
212014
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