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Wai Cheung Chan
Wai Cheung Chan
Senior Research Scientist, Odyssey Therapeutics
Verified email at odysseytx.com
Title
Cited by
Cited by
Year
Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism
NJ Schauer, X Liu, RS Magin, LM Doherty, WC Chan, SB Ficarro, W Hu, ...
Scientific Reports 10 (1), 1-15, 2020
812020
Chemoproteomic methods for covalent drug discovery
WC Chan, S Sharifzadeh, SJ Buhrlage, JA Marto
Chemical Society Reviews 50 (15), 8361-8381, 2021
262021
Identification and validation of selective deubiquitinase inhibitors
AC Varca, D Casalena, WC Chan, B Hu, RS Magin, RM Roberts, X Liu, ...
Cell Chemical Biology 28 (12), 1758-1771. e13, 2021
232021
Accelerating inhibitor discovery for deubiquitinating enzymes
WC Chan, X Liu, RS Magin, NM Girardi, SB Ficarro, W Hu, ...
Nature Communications 14 (1), 686, 2023
222023
Small molecule inhibition of deubiquitinating enzyme JOSD1 as a novel targeted therapy for leukemias with mutant JAK2
J Yang, EL Weisberg, X Liu, RS Magin, WC Chan, B Hu, NJ Schauer, ...
Leukemia 36 (1), 210-220, 2022
142022
Small molecules as tools for functional assessment of deubiquitinating enzyme function
RS Magin, X Liu, A Felix, AS Bratt, WC Chan, SJ Buhrlage
Cell Chemical Biology 28 (7), 1090-1100, 2021
92021
Chemical activation of divergent protein tyrosine phosphatase domains with cyanine-based biarsenicals
BA Plaman, WC Chan, AC Bishop
Scientific reports 9 (1), 1-14, 2019
62019
Activation of Engineered Protein Tyrosine Phosphatases with the Biarsenical Compound AsCy3‐EDT2
WC Chan, GS Knowlton, AC Bishop
ChemBioChem 18 (19), 1950-1958, 2017
42017
On-Chip Preconcentration Microchip Capillary Electrophoresis Based CE-PRM-LIVE for High-Throughput Selectivity Profiling of Deubiquitinase Inhibitors
JAM He Zhu, J. Scott Mellors, Wai Cheung Chan, J. Will Thompson, Scott B ...
Analytical Chemistry, 2022
22022
Chemoproteomic target-class drug discovery against the deubiquitinating enzymes
WC Chan
2022
Biarsenical-induced activation of engineered protein tyrosine phosphatases (PTPs)
B Plaman, WC Chan, A Bishop
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019
2019
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