Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism NJ Schauer, X Liu, RS Magin, LM Doherty, WC Chan, SB Ficarro, W Hu, ... Scientific Reports 10 (1), 1-15, 2020 | 81 | 2020 |
Chemoproteomic methods for covalent drug discovery WC Chan, S Sharifzadeh, SJ Buhrlage, JA Marto Chemical Society Reviews 50 (15), 8361-8381, 2021 | 26 | 2021 |
Identification and validation of selective deubiquitinase inhibitors AC Varca, D Casalena, WC Chan, B Hu, RS Magin, RM Roberts, X Liu, ... Cell Chemical Biology 28 (12), 1758-1771. e13, 2021 | 23 | 2021 |
Accelerating inhibitor discovery for deubiquitinating enzymes WC Chan, X Liu, RS Magin, NM Girardi, SB Ficarro, W Hu, ... Nature Communications 14 (1), 686, 2023 | 22 | 2023 |
Small molecule inhibition of deubiquitinating enzyme JOSD1 as a novel targeted therapy for leukemias with mutant JAK2 J Yang, EL Weisberg, X Liu, RS Magin, WC Chan, B Hu, NJ Schauer, ... Leukemia 36 (1), 210-220, 2022 | 14 | 2022 |
Small molecules as tools for functional assessment of deubiquitinating enzyme function RS Magin, X Liu, A Felix, AS Bratt, WC Chan, SJ Buhrlage Cell Chemical Biology 28 (7), 1090-1100, 2021 | 9 | 2021 |
Chemical activation of divergent protein tyrosine phosphatase domains with cyanine-based biarsenicals BA Plaman, WC Chan, AC Bishop Scientific reports 9 (1), 1-14, 2019 | 6 | 2019 |
Activation of Engineered Protein Tyrosine Phosphatases with the Biarsenical Compound AsCy3‐EDT2 WC Chan, GS Knowlton, AC Bishop ChemBioChem 18 (19), 1950-1958, 2017 | 4 | 2017 |
On-Chip Preconcentration Microchip Capillary Electrophoresis Based CE-PRM-LIVE for High-Throughput Selectivity Profiling of Deubiquitinase Inhibitors JAM He Zhu, J. Scott Mellors, Wai Cheung Chan, J. Will Thompson, Scott B ... Analytical Chemistry, 2022 | 2 | 2022 |
Chemoproteomic target-class drug discovery against the deubiquitinating enzymes WC Chan | | 2022 |
Biarsenical-induced activation of engineered protein tyrosine phosphatases (PTPs) B Plaman, WC Chan, A Bishop ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |