Conjugates of anticancer agents and polymers: advantages of macromolecular therapeutics in vivo H Maeda, LW Seymour, Y Miyamoto Bioconjugate chemistry 3 (5), 351-362, 1992 | 747 | 1992 |
Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor/. bul. NO (nitric oxide) through a radical reaction T Akaike, M Yoshida, Y Miyamoto, K Sato, M Kohno, K Sasamoto, ... Biochemistry 32 (3), 827-832, 1993 | 679 | 1993 |
Activation of matrix metalloproteinases by peroxynitrite-induced protein S-glutathiolation via disulfide S-oxide formation T Okamoto, T Akaike, T Sawa, Y Miyamoto, A Van der Vliet, H Maeda Journal of Biological Chemistry 276 (31), 29596-29602, 2001 | 546 | 2001 |
Influence of molecular weight on passive tumour accumulation of a soluble macromolecular drug carrier LW Seymour, Y Miyamoto, H Maeda, M Brereton, J Strohalm, K Ulbrich, ... European Journal of Cancer 31 (5), 766-770, 1995 | 449 | 1995 |
Nitrosothiol formation catalyzed by ceruloplasmin: implication for cytoprotective mechanism in vivo K Inoue, T Akaike, Y Miyamoto, T Okamoto, T Sawa, M Otagiri, S Suzuki, ... Journal of Biological Chemistry 274 (38), 27069-27075, 1999 | 253 | 1999 |
Antiapoptotic effect of haem oxygenase-1 induced by nitric oxide in experimental solid tumour S Tanaka, T Akaike, J Fang, T Beppu, M Ogawa, F Tamura, Y Miyamoto, ... British Journal of Cancer 88 (6), 902-909, 2003 | 226 | 2003 |
Role of nitric oxide in host defense in murine salmonellosis as a function of its antibacterial and antiapoptotic activities MS Alam, T Akaike, S Okamoto, T Kubota, J Yoshitake, T Sawa, ... Infection and immunity 70 (6), 3130-3142, 2002 | 202 | 2002 |
Pegylated zinc protoporphyrin: a water-soluble heme oxygenase inhibitor with tumor-targeting capacity SK Sahoo, T Sawa, J Fang, S Tanaka, Y Miyamoto, T Akaike, H Maeda Bioconjugate chemistry 13 (5), 1031-1038, 2002 | 187 | 2002 |
Helicobacter pylori Urease Suppresses Bactericidal Activity of Peroxynitrite via Carbon Dioxide Production H Kuwahara, Y Miyamoto, T Akaike, T Kubota, T Sawa, S Okamoto, ... Infection and Immunity 68 (8), 4378-4383, 2000 | 156 | 2000 |
Bactericidal activity of alkyl peroxyl radicals generated by heme-iron-catalyzed decomposition of organic peroxides T Akaike, K Sato, S Ijiri, Y Miyamoto, M Kohno, M Ando, H Maeda Archives of biochemistry and biophysics 294 (1), 55-63, 1992 | 144 | 1992 |
Enhancement of bone morphogenetic protein-2-induced ectopic bone formation by transforming growth factor-β1 K Tachi, M Takami, H Sato, A Mochizuki, B Zhao, Y Miyamoto, ... Tissue engineering Part A 17 (5-6), 597-606, 2011 | 137 | 2011 |
Viral mutation accelerated by nitric oxide production during infection in vivo T Akaike, S Fujii, A Kato, J Yoshitake, Y Miyamoto, T Sawa, S Okamoto, ... The FASEB Journal 14 (10), 1447-1454, 2000 | 128 | 2000 |
Augmentation of tumour delivery of macromolecular drugs with reduced bone marrow delivery by elevating blood pressure CJ Li, Y Miyamoto, Y Kojima, H Maeda British journal of cancer 67 (5), 975-980, 1993 | 124 | 1993 |
Interleukin-1β induces death in chondrocyte-like ATDC5 cells through mitochondrial dysfunction and energy depletion in a reactive nitrogen and oxygen species-dependent manner R Yasuhara, Y Miyamoto, T Akaike, T Akuta, M Nakamura, M Takami, ... Biochemical Journal 389 (2), 315-323, 2005 | 122 | 2005 |
Identification of bradykinin receptors in clinical cancer specimens and murine tumor tissues J Wu, T Akaike, K Hayashida, Y Miyamoto, T Nakagawa, K Miyakawa, ... International journal of cancer 98 (1), 29-35, 2002 | 120 | 2002 |
Potentiation of nitric oxide—mediated Vasorelaxation by xanthine oxidase inhibitors Y Miyamoto, T Akaike, M Yoshida, S Goto, H Horie, H Maeda Proceedings of the Society for Experimental Biology and Medicine 211 (4 …, 1996 | 112 | 1996 |
Interleukin‐4 inhibition of osteoclast differentiation is stronger than that of interleukin‐13 and they are equivalent for induction of osteoprotegerin production from osteoblasts A Yamada, M Takami, T Kawawa, R Yasuhara, B Zhao, A Mochizuki, ... Immunology 120 (4), 573-579, 2007 | 106 | 2007 |
Osteoclast differentiation induced by synthetic octacalcium phosphate through receptor activator of NF-κB ligand expression in osteoblasts M Takami, A Mochizuki, A Yamada, K Tachi, B Zhao, Y Miyamoto, ... Tissue Engineering Part A 15 (12), 3991-4000, 2009 | 72 | 2009 |
S-Nitrosylation of human variant albumin Liprizzi (R410C) confers potent antibacterial and cytoprotective properties Y Ishima, T Sawa, U Kragh-Hansen, Y Miyamoto, S Matsushita, T Akaike, ... Journal of Pharmacology and Experimental Therapeutics 320 (3), 969-977, 2007 | 66 | 2007 |
Protective effect of S-nitrosylated α1-protease inhibitor on hepatic ischemia-reperfusion injury N Ikebe, T Akaike, Y Miyamoto, K Hayashida, J Yoshitake, M Ogawa, ... Journal of Pharmacology and Experimental Therapeutics 295 (3), 904-911, 2000 | 66 | 2000 |