| Innovative approaches for the development of antidepressant drugs: current and future strategies LE Schechter, RH Ring, CE Beyer, ZA Hughes, X Khawaja, JE Malberg, ... NeuroRx 2 (4), 590-611, 2005 | 334 | 2005 |
| Evidence for sustained elevation of IL-6 in the CNS as a key contributor of depressive-like phenotypes SJ Sukoff Rizzo, SJ Neal, ZA Hughes, M Beyna, S Rosenzweig-Lipson, ... Translational psychiatry 2 (12), e199-e199, 2012 | 256 | 2012 |
| Histidine decarboxylase deficiency causes tourette syndrome: parallel findings in humans and mice LC Baldan, KA Williams, JD Gallezot, V Pogorelov, M Rapanelli, ... Neuron 81 (1), 77-90, 2014 | 251 | 2014 |
| Differentiating antidepressants of the future: efficacy and safety S Rosenzweig-Lipson, CE Beyer, ZA Hughes, X Khawaja, SJ Rajarao, ... Pharmacology & therapeutics 113 (1), 134-153, 2007 | 249 | 2007 |
| Effects of atomoxetine and methylphenidate on attention and impulsivity in the 5-choice serial reaction time test R Navarra, R Graf, Y Huang, S Logue, T Comery, Z Hughes, M Day Progress in Neuro-Psychopharmacology and Biological Psychiatry 32 (1), 34-41, 2008 | 211 | 2008 |
| BACE1 (β-secretase) transgenic and knockout mice: identification of neurochemical deficits and behavioral changes SM Harrison, AJ Harper, J Hawkins, G Duddy, E Grau, PL Pugh, ... Molecular and Cellular Neuroscience 24 (3), 646-655, 2003 | 190 | 2003 |
| Receptor and behavioral pharmacology of WAY-267464, a non-peptide oxytocin receptor agonist RH Ring, LE Schechter, SK Leonard, JM Dwyer, BJ Platt, R Graf, S Grauer, ... Neuropharmacology 58 (1), 69-77, 2010 | 168 | 2010 |
| Critical data‐based re‐evaluation of minocycline as a putative specific microglia inhibitor T Möller, F Bard, A Bhattacharya, K Biber, B Campbell, E Dale, C Eder, ... Glia 64 (10), 1788-1794, 2016 | 165 | 2016 |
| LPA1 receptor-deficient mice have phenotypic changes observed in psychiatric disease SM Harrison, C Reavill, G Brown, JT Brown, JE Cluderay, B Crook, ... Molecular and Cellular Neuroscience 24 (4), 1170-1179, 2003 | 159 | 2003 |
| Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/serotonin reuptake inhibitor, vilazodone ZA Hughes, KR Starr, CJ Langmead, M Hill, GD Bartoszyk, JJ Hagan, ... European journal of pharmacology 510 (1-2), 49-57, 2005 | 150 | 2005 |
| Inflammatory biomarkers in Alzheimer's disease plasma AR Morgan, S Touchard, C Leckey, C O'Hagan, AJ Nevado-Holgado, ... Alzheimer's & dementia 15 (6), 776-787, 2019 | 140 | 2019 |
| The BTBR mouse model of autism spectrum disorders has learning and attentional impairments and alterations in acetylcholine and kynurenic acid in prefrontal cortex SM McTighe, SJ Neal, Q Lin, ZA Hughes, DG Smith PloS one 8 (4), e62189, 2013 | 132 | 2013 |
| The metabotropic glutamate receptor 7 allosteric modulator AMN082: a monoaminergic agent in disguise? SJS Rizzo, SK Leonard, A Gilbert, P Dollings, DL Smith, MY Zhang, L Di, ... Journal of Pharmacology and Experimental Therapeutics 338 (1), 345-352, 2011 | 110 | 2011 |
| Central effects of urotensin-II following ICV administration in rats J Gartlon, F Parker, DC Harrison, SA Douglas, TE Ashmeade, GJ Riley, ... Psychopharmacology 155, 426-433, 2001 | 104 | 2001 |
| The orphan GPCR, GPR88, modulates function of the striatal dopamine system: a possible therapeutic target for psychiatric disorders? SF Logue, SM Grauer, J Paulsen, R Graf, N Taylor, MA Sung, L Zhang, ... Molecular and Cellular Neuroscience 42 (4), 438-447, 2009 | 98 | 2009 |
| WAY-200070, a selective agonist of estrogen receptor beta as a potential novel anxiolytic/antidepressant agent ZA Hughes, F Liu, BJ Platt, JM Dwyer, CM Pulicicchio, G Zhang, ... Neuropharmacology 54 (7), 1136-1142, 2008 | 95 | 2008 |
| Increased responsiveness of dopamine to atypical, but not typical antipsychotics in the medial prefrontal cortex of rats reared in isolation CA Heidbreder, R Foxton, J Cilia, ZA Hughes, AJ Shah, A Atkins, ... Psychopharmacology 156, 338-351, 2001 | 95 | 2001 |
| High-performance liquid chromatography/tandem mass spectrometry assay for the rapid high sensitivity measurement of basal acetylcholine from microdialysates MEP Hows, AJ Organ, S Murray, LA Dawson, R Foxton, C Heidbreder, ... Journal of neuroscience methods 121 (1), 33-39, 2002 | 86 | 2002 |
| Negative allosteric modulation of metabotropic glutamate receptor 5 results in broad spectrum activity relevant to treatment resistant depression ZA Hughes, SJ Neal, DL Smith, SJS Rizzo, CM Pulicicchio, S Lotarski, ... Neuropharmacology 66, 202-214, 2013 | 84 | 2013 |
| Development of a liquid chromatography/tandem mass spectrometry method for the quantitation of acetylcholine and related neurotransmitters in brain microdialysis samples MY Zhang, ZA Hughes, EH Kerns, Q Lin, CE Beyer Journal of pharmaceutical and biomedical analysis 44 (2), 586-593, 2007 | 83 | 2007 |
