| Capsid-CPSF6 interaction licenses nuclear HIV-1 trafficking to sites of viral DNA integration V Achuthan, JM Perreira, GA Sowd, M Puray-Chavez, WM McDougall, ... Cell Host & Microbe 24 (3), 392-404. e8, 2018 | 187 | 2018 |
| HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains AC Francis, M Marin, PK Singh, V Achuthan, MJ Prellberg, ... Nature communications 11 (1), 3505, 2020 | 129 | 2020 |
| CPSF6-dependent targeting of speckle-associated domains distinguishes primate from nonprimate lentiviral integration W Li, PK Singh, GA Sowd, GJ Bedwell, S Jang, V Achuthan, AV Oleru, ... MBio 11 (5), 10.1128/mbio. 02254-20, 2020 | 32 | 2020 |
| Human Immunodeficiency Virus Reverse Transcriptase Displays Dramatically Higher Fidelity under Physiological Magnesium Conditions In Vitro V Achuthan, BJ Keith, BA Connolly, JJ DeStefano Journal of Virology 88 (15), 8514-8527, 2014 | 32 | 2014 |
| Capsid-CPSF6 interaction: Master regulator of nuclear HIV-1 positioning and integration V Achuthan, JM Perreira, JJ Ahn, AL Brass, AN Engelman Journal of life sciences (Westlake Village, Calif.) 1 (1), 39, 2019 | 20 | 2019 |
| Disrupting MLV integrase: BET protein interaction biases integration into quiescent chromatin and delays but does not eliminate tumor activation in a MYC/Runx2 mouse model L Loyola, V Achuthan, K Gilroy, G Borland, A Kilbey, N Mackay, M Bell, ... PLoS pathogens 15 (12), e1008154, 2019 | 13 | 2019 |
| Alternative divalent cations (Zn2+, Co2+, and Mn2+) are not mutagenic at conditions optimal for HIV-1 reverse transcriptase activity V Achuthan, JJ DeStefano BMC biochemistry 16, 1-14, 2015 | 12 | 2015 |
| Intra-and extra-cellular environments contribute to the fate of HIV-1 infection S Ratnapriya, M Harris, A Chov, ZT Herbert, V Vrbanac, M Deruaz, ... Cell reports 36 (9), 2021 | 11 | 2021 |
| HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains. Nat Commun 11: 3505 AC Francis, M Marin, PK Singh, V Achuthan, MJ Prellberg, ... | 11 | 2020 |
| Physiological Mg2+ Conditions Significantly Alter the Inhibition of HIV-1 and HIV-2 Reverse Transcriptases by Nucleoside and Non-Nucleoside Inhibitors in Vitro V Achuthan, K Singh, JJ DeStefano Biochemistry 56 (1), 33-46, 2017 | 9 | 2017 |
| Genome-wide CRISPR/Cas9 transcriptional activation screen identifies a histone acetyltransferase inhibitor complex as a regulator of HIV-1 integration Q Zhang, S Wang, W Li, E Yau, H Hui, PK Singh, V Achuthan, ... Nucleic acids research 50 (12), 6687-6701, 2022 | 8 | 2022 |
| HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains. Nat Commun. 2020; 11 (1): 3505 AC Francis, M Marin, PK Singh, V Achuthan, MJ Prellberg, ... Epub 2020/07/16. https://doi. org/10.1038/s41467-020-17256-8 PMID: 32665593, 0 | 8 | |
| CPSF6-Dependent Targeting of Speckle-Associated Domains Distinguishes Primate from Nonprimate Lentiviral Integration. mBio. 2020; 11 (5) W Li, PK Singh, GA Sowd, GJ Bedwell, S Jang, V Achuthan, AV Oleru, ... PMC7527728, 0 | 8 | |
| An Evolutionary/Biochemical connection between promoter-and primer-dependent polymerases revealed by systematic evolution of ligands by exponential enrichment KJ Fenstermacher, V Achuthan, TD Schneider, JJ DeStefano Journal of bacteriology 200 (7), 10.1128/jb. 00579-17, 2018 | 2 | 2018 |
| Mismatched Primer Extension Assays V Achuthan, JJ DeStefano Bio-protocol 5 (12), e1508-e1508, 2015 | 1 | 2015 |
| Physiological magnesium concentrations increase fidelity of diverse reverse transcriptases from HIV-1, HIV-2, and foamy virus, but not MuLV or AMV R Wang, AT Belew, V Achuthan, N El Sayed, JJ DeStefano Journal of General Virology 102 (12), 001708, 2021 | | 2021 |
| Cleavage and polyadenylation specific factor 6 is required for HIV latency reversal Y Zheng, A Nau, V Achuthan, A Engelman, V Planelles | | 2019 |
| HIV Reverse Transcriptase Fidelity And Inhibition Are Modulated By Divalent Cations In A Concentration-Dependent Manner In Vitro V Achuthan University of Maryland, 2016 | | 2016 |
| Primer Extension Reactions for the PCR-based α-complementation Assay V Achuthan, JJ DeStefano Bio-protocol 5 (12), e1509-e1509, 2015 | | 2015 |
