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Appasaheb L. Kadam
Appasaheb L. Kadam
Senior Research Scientist at Adesis Inc.
Verified email at adesisinc.com - Homepage
Title
Cited by
Cited by
Year
Toward a practical, two-step process for molnupiravir: Direct hydroxamination of cytidine followed by selective esterification
DJ Paymode, N Vasudevan, S Ahmad, AL Kadam, FSP Cardoso, ...
Organic Process Research & Development 25 (8), 1822-1830, 2021
392021
Enantioselective Formal Total Synthesis of (−)-Quinagolide
SP Chavan, AL Kadam, RG Gonnade
Organic letters 21 (22), 9089-9093, 2019
152019
Synthesis of 3-Azidopiperidine Skeleton Employing Ceric Ammonium Nitrate (CAN)-Mediated Regioselective Azidoalkoxylation of Enol Ether: Total Synthesis of D2 Receptor Agonist …
SP Chavan, AL Kadam, PB Lasonkar, RG Gonnade
Organic letters 20 (22), 7011-7014, 2018
152018
Toward a practical, nonenzymatic process for investigational COVID-19 antiviral molnupiravir from cytidine: Supply-centered synthesis
V Gopalsamuthiram, AL Kadam, JK Noble, DR Snead, C Williams, ...
Organic Process Research & Development 25 (12), 2679-2685, 2021
112021
Furan‐Derived Chiral Bicycloaziridino Lactone Synthon: Collective Syntheses of Oseltamivir Phosphate (Tamiflu), (S)‐Pipecolic acid and its 3‐Hydroxy Derivatives
SP Chavan, AL Kadam, SS Shinde, RG Gonnade
Chemistry–An Asian Journal 15 (3), 415-424, 2020
102020
Total Synthesis of (±)-Quinagolide: A Potent D2 Receptor Agonist for the Treatment of Hyperprolactinemia
SP Chavan, AL Kadam, SA Kawale
ACS omega 4 (5), 8231-8238, 2019
102019
Formal Synthesis of (−)-Quinagolide: Diastereoselective Ring Expansion via a Bicyclic Aziridinium Ion Strategy to Access the Octahydrobenzo[g]quinoline …
SP Chavan, SA Kawale, MM Pisal, AL Kadam, RG Gonnade
The Journal of Organic Chemistry 86 (14), 9344-9352, 2021
82021
Efforts to develop a cost-effective and scalable synthetic process for nirmatrelvir
CS Shanahan, AL Kadam, B Chiranjeevi, AA Nunes, A Jayaraman, ...
American Chemical Society (ACS), 2022
62022
A Facile and Convenient Synthesis of (±)-Biotin via MgCl2/Et3N-Mediated C–C Coupling and Mitsunobu Reaction
SP Chavan, PN Chavan, PB Lasonkar, LB Khairnar, AL Kadam
Synlett 25 (20), 2879-2882, 2014
52014
Practical and Scalable Two-Step Process for 6-(2-Fluoro-4-nitrophenyl)-2-oxa-6-azaspiro [3.3] heptane: A Key Intermediate of the Potent Antibiotic Drug Candidate TBI-223
FSP Cardoso, AL Kadam, RC Nelson, JW Tomlin, D Dahal, CS Kuehner, ...
Organic Process Research & Development 27 (7), 1390-1399, 2023
22023
Scalable Synthesis of 3-Ethyl-4-methyl-1, 5-dihydro-2H-pyrrol-2-one: An Important Building Block of the Antidiabetic Drug Glimepiride
SP Chavan, AA Pawar, NB Patil, AL Kadam, SS Shinde
Synthesis 52 (22), 3480-3484, 2020
22020
Practical synthesis of 5-hydroxy-2(5H)-furanone from furan
SP Chavan, AL Kadam
Results in Chemistry 3, 100170, 2021
12021
Towards a practical, non-enzymatic process for molnupiravir from cytidine
V Gopalsamuthiram, AL Kadam, J Noble, D Snead, C Williams, ...
12021
Correction to “Toward a Practical, Nonenzymatic Process for Investigational COVID-19 Antiviral Molnupiravir from Cytidine: Supply-Centered Synthesis”
V Gopalsamuthiram, AL Kadam, JM Noble, DR Snead, C Williams, ...
Organic Process Research & Development 27 (7), 1420-1420, 2023
2023
Revisiting Classical Pummerer Cyclization Reaction: A Key Strategy for the Synthesis of (±)‐Quinagolide
SP Chavan, SA Kawale, A Tripathi, AL Kadam, RG Gonnade
ChemistrySelect 7 (28), e202201600, 2022
2022
Toward a Practical, Two-Step Process for Molnupiravir from Cytidine
DJ Paymode, N Vasudevan, S Ahmad, AL Kadam, FSP Cardoso, J Burns, ...
2021
Design & tactics for total synthesis of D2 receptor agonist quinagolide & development and application of on-water oxidation of furan in collective synthesis of bioactive …
AL Kadam
CSIR-National Chemical Laboratory, 2019
2019
Process for the Preparation of Sacubitril Intermediates
R Kontham, SP Chavan, SS Thorat, AL Kadam
IN Patent App. 201,911,043,858, 2019
2019
An Improved Process for Synthesis of 3-Ethyl-4-methyl-1,5-dihydro-2H-pyrrol-2-one
SP Chavan, AA Pawar, NB Patil, AL Kadam, SS Shinde
IN Patent App. 201,911,040,874, 2019
2019
Synthesis of 5-Hydroxy-2(5H)-furanone from Furan
SP Chavan, AL Kadam
IN Patent App. 201,911,033,067, 2019
2019
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