Vascularized organoids on a chip: strategies for engineering organoids with functional vasculature S Zhang, Z Wan, RD Kamm Lab on a Chip 21 (3), 473-488, 2021 | 194 | 2021 |
B cell activation is regulated by the stiffness properties of the substrate presenting the antigens Z Wan, S Zhang, Y Fan, K Liu, F Du, AM Davey, H Zhang, W Han, C Xiong, ... The Journal of Immunology 190 (9), 4661-4675, 2013 | 120 | 2013 |
The activation of IgM-or isotype-switched IgG-and IgE-BCR exhibits distinct mechanical force sensitivity and threshold Z Wan, X Chen, H Chen, Q Ji, Y Chen, J Wang, Y Cao, F Wang, J Lou, ... Elife 4, e06925, 2015 | 109 | 2015 |
Substrate stiffness regulates B‐cell activation, proliferation, class switch, and T‐cell‐independent antibody responses in vivo Y Zeng, J Yi, Z Wan, K Liu, P Song, A Chau, F Wang, Z Chang, W Han, ... European journal of immunology 45 (6), 1621-1634, 2015 | 90 | 2015 |
Profiling the origin, dynamics, and function of traction force in B cell activation J Wang, F Lin, Z Wan, X Sun, Y Lu, J Huang, F Wang, Y Zeng, YH Chen, ... Science Signaling 11 (542), eaai9192, 2018 | 67 | 2018 |
The scaffolding protein synapse-associated protein 97 is required for enhanced signaling through isotype-switched IgG memory B cell receptors W Liu, E Chen, XW Zhao, ZP Wan, YR Gao, A Davey, E Huang, L Zhang, ... Science signaling 5 (235), ra54-ra54, 2012 | 65 | 2012 |
Substrate stiffness governs the initiation of B cell activation by the concerted signaling of PKCβ and focal adhesion kinase S Shaheen, Z Wan (co-1st author), Z Li, A Chau, X Li, S Zhang, Y Liu, J Yi, ... eLife 6, 2017 | 54 | 2017 |
The cancer glycocalyx mediates intravascular adhesion and extravasation during metastatic dissemination GS Offeddu, C Hajal, CR Foley, Z Wan, L Ibrahim, MF Coughlin, ... Communications biology 4 (1), 255, 2021 | 43 | 2021 |
Through an ITIM-independent mechanism the FcγRIIB blocks B cell activation by disrupting the colocalized microclustering of the B cell receptor and CD19 L Xu, G Li, J Wang, Y Fan, Z Wan, S Zhang, S Shaheen, J Li, L Wang, ... The Journal of Immunology 192 (11), 5179-5191, 2014 | 42 | 2014 |
Interstitial Flow Promotes the Formation of Functional Microvascular Networks In Vitro through Upregulation of Matrix Metalloproteinase‐2 S Zhang, Z Wan (co-1st author), G Pavlou, AX Zhong, L Xu, RD Kamm Advanced Functional Materials, 2206767, 2022 | 37 | 2022 |
A robust method for perfusable microvascular network formation in vitro Z Wan, AX Zhong, S Zhang, G Pavlou, MF Coughlin, SE Shelton, ... Small Methods 6 (6), 2200143, 2022 | 35 | 2022 |
Total chemical synthesis of photoactivatable proteins for light-controlled manipulation of antigen–antibody interactions S Tang, Z Wan (co-1st author), Y Gao, JS Zheng, J Wang, YY Si, X Chen, ... Chemical Science 7 (3), 1891-1895, 2016 | 30 | 2016 |
A robust vasculogenic microfluidic model using human immortalized endothelial cells and Thy1 positive fibroblasts Z Wan, S Zhang, AX Zhong, SE Shelton, M Campisi, SK Sundararaman, ... Biomaterials 276, 121032, 2021 | 29 | 2021 |
PI (4, 5) P2 determines the threshold of mechanical force–induced B cell activation Z Wan, C Xu, X Chen, H Xie, Z Li, J Wang, X Ji, H Chen, Q Ji, S Shaheen, ... Journal of Cell Biology 217 (7), 2565-2582, 2018 | 28 | 2018 |
New strategy for promoting vascularization in tumor spheroids in a microfluidic assay Z Wan, MA Floryan, MF Coughlin, S Zhang, AX Zhong, SE Shelton, ... Advanced healthcare materials 12 (14), 2201784, 2023 | 27 | 2023 |
Utilization of a photoactivatable antigen system to examine B-cell probing termination and the B-cell receptor sorting mechanisms during B-cell activation J Wang, S Tang, Z Wan, Y Gao, Y Cao, J Yi, Y Si, H Zhang, L Liu, W Liu Proceedings of the National Academy of Sciences 113 (5), E558-E567, 2016 | 27 | 2016 |
Conformational change within the extracellular domain of B cell receptor in B cell activation upon antigen binding Z Shen, S Liu, X Li, Z Wan, Y Mao, C Chen, W Liu Elife 8, e42271, 2019 | 26 | 2019 |
The growth of B cell receptor microcluster is a universal response of B cells encountering antigens with different motion features Z Wan, W Liu Protein & Cell 3 (7), 545-558, 2012 | 25 | 2012 |
A novel 3D vascular assay for evaluating angiogenesis across porous membranes J Bai, K Haase, JJ Roberts, J Hoffmann, HT Nguyen, Z Wan, S Zhang, ... Biomaterials 268, 120592, 2021 | 18 | 2021 |
Age-related alterations in meningeal immunity drive impaired CNS lymphatic drainage J Rustenhoven, G Pavlou, SE Storck, T Dykstra, S Du, Z Wan, D Quintero, ... Journal of Experimental Medicine 220 (7), e20221929, 2023 | 17 | 2023 |