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Lok Yin Roy Wong
Lok Yin Roy Wong
New Jersey Medical School, Rutgers University
Verified email at rutgers.edu - Homepage
Title
Cited by
Cited by
Year
SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters
PJ Halfmann, S Iida, K Iwatsuki-Horimoto, T Maemura, M Kiso, ...
Nature 603 (7902), 687-692, 2022
5562022
COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice
J Zheng, LYR Wong, K Li, AK Verma, ME Ortiz, C Wohlford-Lenane, ...
Nature 589 (7843), 603-607, 2021
4742021
Generation of a broadly useful model for COVID-19 pathogenesis, vaccination, and treatment
J Sun, Z Zhuang, J Zheng, K Li, RLY Wong, D Liu, J Huang, J He, A Zhu, ...
Cell 182 (3), 734-743. e5, 2020
4712020
Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses—are we our own worst enemy?
LYR Wong, S Perlman
Nature Reviews Immunology 22 (1), 47-56, 2022
1762022
Middle East respiratory syndrome coronavirus M protein suppresses type I interferon expression through the inhibition of TBK1-dependent phosphorylation of IRF3
PY Lui, LYR Wong, CL Fung, KL Siu, ML Yeung, KS Yuen, CP Chan, ...
Emerging microbes & infections 5 (1), 1-9, 2016
1392016
Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19
LYR Wong, J Zheng, K Wilhelmsen, K Li, ME Ortiz, NJ Schnicker, ...
Nature 605 (7908), 146-151, 2022
1182022
The SARS-CoV-2 B. 1.1. 529 Omicron virus causes attenuated infection and disease in mice and hamsters
M Diamond, P Halfmann, T Maemura, K Iwatsuki-Horimoto, S Iida, M Kiso, ...
Research square, 2021
1172021
Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection
CS Dampalla, J Zheng, KD Perera, LYR Wong, DK Meyerholz, ...
Proceedings of the National Academy of Sciences 118 (29), e2101555118, 2021
812021
A molecular arms race between host innate antiviral response and emerging human coronaviruses
LYR Wong, PY Lui, DY Jin
Virologica Sinica 31, 12-23, 2016
672016
PACT facilitates RNA-induced activation of MDA5 by promoting MDA5 oligomerization
PY Lui, LYR Wong, TH Ho, SWN Au, CP Chan, KH Kok, DY Jin
The Journal of Immunology 199 (5), 1846-1855, 2017
462017
Middle East respiratory syndrome coronavirus ORF8b accessory protein suppresses type I IFN expression by impeding HSP70-dependent activation of IRF3 kinase IKKε
LYR Wong, ZW Ye, PY Lui, X Zheng, S Yuan, L Zhu, SY Fung, KS Yuen, ...
The Journal of Immunology 205 (6), 1564-1579, 2020
422020
Eicosanoid signaling as a therapeutic target in middle-aged mice with severe COVID-19
LYR Wong, J Zheng, K Wilhelmsen, K Li, ME Ortiz, NJ Schnicker, ...
bioRxiv, 2021
262021
Sensitization of non-permissive laboratory mice to SARS-CoV-2 with a replication-deficient adenovirus expressing human ACE2
LYR Wong, K Li, J Sun, Z Zhuang, J Zhao, PB McCray Jr, S Perlman
STAR protocols 1 (3), 100169, 2020
212020
Omicron subvariant BA. 5 efficiently infects lung cells
M Hoffmann, LYR Wong, P Arora, L Zhang, C Rocha, A Odle, I Nehlmeier, ...
Nature communications 14 (1), 3500, 2023
202023
K18-hACE2 mice for studies of COVID-19 treatments and pathogenesis including anosmia
J Zheng, LY Roy Wong, K Li, AK Verma, M Ortiz, C Wohlford-Lenane, ...
BioRxiv, 2020.08. 07.242073, 2020
152020
Nsp3-N interactions are critical for SARS-CoV-2 fitness and virulence
P Li, B Xue, NJ Schnicker, LYR Wong, DK Meyerholz, S Perlman
Proceedings of the National Academy of Sciences 120 (31), e2305674120, 2023
142023
Coronavirus-specific antibody production in middle-aged mice requires phospholipase A2G2D
J Zheng, D Meyerholz, LYR Wong, M Gelb, M Murakami, S Perlman
The Journal of clinical investigation 131 (11), 2021
132021
SARS-CoV-2-specific immunoglobulin Y antibodies are protective in infected mice
SA El-Kafrawy, A Odle, AT Abbas, AM Hassan, UA Abdel-Dayem, ...
PLoS pathogens 18 (9), e1010782, 2022
122022
Middle East respiratory syndrome coronavirus Spike protein variants exhibit geographic differences in virulence
LYR Wong, J Zheng, A Sariol, S Lowery, DK Meyerholz, T Gallagher, ...
Proceedings of the National Academy of Sciences 118 (24), e2102983118, 2021
122021
Identification of lysine acetylation sites on MERS-CoV replicase pp1ab
L Zhu, SY Fung, G Xie, LYR Wong, DY Jin, Z Cai
Molecular & Cellular Proteomics 19 (8), 1303-1309, 2020
122020
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Articles 1–20