| Under normoxia, 2-deoxy-d-glucose elicits cell death in select tumor types not by inhibition of glycolysis but by interfering with N-linked glycosylation M Kurtoglu, N Gao, J Shang, JC Maher, MA Lehrman, M Wangpaichitr, ... Molecular cancer therapeutics 6 (11), 3049-3058, 2007 | 295 | 2007 |
| Arginine deprivation as a targeted therapy for cancer L Feun, M You, CJ Wu, MT Kuo, M Wangpaichitr, S Spector, N Savaraj Current pharmaceutical design 14 (11), 1049-1057, 2008 | 278 | 2008 |
| 2-Deoxy-d-glucose activates autophagy via endoplasmic reticulum stress rather than ATP depletion H Xi, M Kurtoglu, H Liu, M Wangpaichitr, M You, X Liu, N Savaraj, ... Cancer chemotherapy and pharmacology 67, 899-910, 2011 | 235 | 2011 |
| Overcoming cisplatin resistance by mTOR inhibitor in lung cancer C Wu, M Wangpaichitr, L Feun, MT Kuo, C Robles, T Lampidis, N Savaraj Molecular cancer 4, 1-10, 2005 | 151 | 2005 |
| Phase 2 study of pembrolizumab and circulating biomarkers to predict anticancer response in advanced, unresectable hepatocellular carcinoma LG Feun, YY Li, C Wu, M Wangpaichitr, PD Jones, SP Richman, ... Cancer 125 (20), 3603-3614, 2019 | 148 | 2019 |
| Evaluation of granular activated carbon technology for the removal of methyl tertiary butyl ether (MTBE) from drinking water TC Shih, M Wangpaichitr, M Suffet Water research 37 (2), 375-385, 2003 | 136 | 2003 |
| Negative argininosuccinate synthetase expression in melanoma tumours may predict clinical benefit from arginine-depleting therapy with pegylated arginine deiminase LG Feun, A Marini, G Walker, G Elgart, F Moffat, SE Rodgers, CJ Wu, ... British journal of cancer 106 (9), 1481-1485, 2012 | 132 | 2012 |
| Hypoxia-inducible factor-1 confers resistance to the glycolytic inhibitor 2-deoxy-d-glucose JC Maher, M Wangpaichitr, N Savaraj, M Kurtoglu, TJ Lampidis Molecular cancer therapeutics 6 (2), 732-741, 2007 | 127 | 2007 |
| Arginine deiminase resistance in melanoma cells is associated with metabolic reprogramming, glucose dependence, and glutamine addiction Y Long, WB Tsai, M Wangpaichitr, T Tsukamoto, N Savaraj, LG Feun, ... Molecular cancer therapeutics 12 (11), 2581-2590, 2013 | 118 | 2013 |
| Arginine deprivation, autophagy, apoptosis (AAA) for the treatment of melanoma N Savaraj, M You, C Wu, M Wangpaichitr, MT Kuo, LG Feun Current molecular medicine 10 (4), 405-412, 2010 | 105 | 2010 |
| Inhibition of mTOR restores cisplatin sensitivity through down-regulation of growth and anti-apoptotic proteins M Wangpaichitr, C Wu, M You, MT Kuo, L Feun, T Lampidis, N Savaraj European journal of pharmacology 591 (1-3), 124-127, 2008 | 90 | 2008 |
| The relationship of thioredoxin-1 and cisplatin resistance: its impact on ROS and oxidative metabolism in lung cancer cells M Wangpaichitr, EJ Sullivan, G Theodoropoulos, C Wu, M You, LG Feun, ... Molecular cancer therapeutics 11 (3), 604-615, 2012 | 87 | 2012 |
| Exploiting ROS and metabolic differences to kill cisplatin resistant lung cancer M Wangpaichitr, C Wu, YY Li, DJM Nguyen, H Kandemir, S Shah, S Chen, ... Oncotarget 8 (30), 49275, 2017 | 83 | 2017 |
| TRAIL induces autophagic protein cleavage through caspase activation in melanoma cell lines under arginine deprivation M You, N Savaraj, MT Kuo, M Wangpaichitr, J Varona-Santos, C Wu, ... Molecular and cellular biochemistry 374, 181-190, 2013 | 79 | 2013 |
| N′1,N′3-Dimethyl-N′1,N′3-bis(phenylcarbonothioyl) Propanedihydrazide (Elesclomol) Selectively Kills Cisplatin Resistant Lung Cancer Cells through … M Wangpaichitr, C Wu, M You, JC Maher, V Dinh, LG Feun, N Savaraj Cancers 1 (1), 23-28, 2009 | 61 | 2009 |
| Redox regulation of matrix metalloproteinase gene family in small cell lung cancer cells N Savaraj, Y Wei, H Unate, PM Liu, CJ Wu, M Wangpaichitr, D Xia, HJ Xu, ... Free radical research 39 (4), 373-381, 2005 | 43 | 2005 |
| Autophagic mechanism in anti-cancer immunity: its pros and cons for cancer therapy YY Li, LG Feun, A Thongkum, CH Tu, SM Chen, M Wangpaichitr, C Wu, ... International journal of molecular sciences 18 (6), 1297, 2017 | 42 | 2017 |
| Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1α, and c-Myc transcription network and is … Y Long, WB Tsai, JT Chang, M Estecio, M Wangpaichitr, N Savaraj, ... Oncotarget 7 (50), 82658, 2016 | 42 | 2016 |
| Overexpression of mutated MRP4 in cisplatin resistant small cell lung cancer cell line: collateral sensitivity to azidothymidine N Savaraj, C Wu, M Wangpaichitr, MT Kuo, T Lampidis, C Robles, ... International journal of oncology 23 (1), 173-179, 2003 | 42 | 2003 |
| Relationship of metabolic alterations and PD-L1 expression in cisplatin resistant lung cancer M Wangpaichitr, H Kandemir, YY Li, C Wu, DJM Nguyen, LG Feun, ... Cell & developmental biology 6 (2), 2017 | 41 | 2017 |
