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| Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease N Panicker, TI Kam, H Wang, S Neifert, SC Chou, M Kumar, ... Neuron 110 (15), 2422-2437. e9, 2022 | 84 | 2022 |
| LRRK2 G2019S transgenic mice display increased susceptibility to 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-mediated neurotoxicity SS Karuppagounder, Y Xiong, Y Lee, MC Lawless, D Kim, E Nordquist, ... Journal of chemical neuroanatomy 76, 90-97, 2016 | 54 | 2016 |
| Defects in mitochondrial biogenesis drive mitochondrial alterations in PARKIN-deficient human dopamine neurons M Kumar, J Acevedo-Cintrón, A Jhaldiyal, H Wang, SA Andrabi, S Eacker, ... Stem Cell Reports 15 (3), 629-645, 2020 | 51 | 2020 |
| Defects in mRNA translation in LRRK2-mutant hiPSC-derived dopaminergic neurons lead to dysregulated calcium homeostasis JW Kim, X Yin, A Jhaldiyal, MR Khan, I Martin, Z Xie, T Perez-Rosello, ... Cell stem cell 27 (4), 633-645. e7, 2020 | 41 | 2020 |
| Enhanced mTORC1 signaling and protein synthesis in pathologic α-synuclein cellular and animal models of Parkinson’s disease MR Khan, X Yin, SU Kang, J Mitra, H Wang, T Ryu, S Brahmachari, ... Science translational medicine 15 (724), eadd0499, 2023 | 2 | 2023 |
Ted M. DawsonDirector, Institute for Cell Engineering, Professor of Neurology and Neuroscience, JHUSoMVerified email at jhmi.edu
