Coumarin-dithiocarbamate hybrids as novel multitarget AChE and MAO-B inhibitors against Alzheimer’s disease: Design, synthesis and biological evaluation Q He, J Liu, JS Lan, J Ding, Y Sun, Y Fang, N Jiang, Z Yang, L Sun, Y Jin, ... Bioorganic Chemistry 81, 512-528, 2018 | 89 | 2018 |
Design and synthesis of novel pyrimido [5, 4-d] pyrimidine derivatives as GPR119 agonist for treatment of type 2 diabetes Y Fang, J Xu, Z Li, Z Yang, L Xiong, Y Jin, Q Wang, S Xie, W Zhu, ... Bioorganic & medicinal chemistry 26 (14), 4080-4087, 2018 | 35 | 2018 |
Synthesis and biological evaluation of 5-nitropyrimidine analogs with azabicyclic substituents as GPR119 agonists Z Yang, Y Fang, TAN Pham, J Lee, H Park Bioorganic & medicinal chemistry letters 23 (5), 1519-1521, 2013 | 29 | 2013 |
Design, synthesis and biological evaluation of coumarin-based N-hydroxycinnamamide derivatives as novel histone deacetylase inhibitors with anticancer activities J Ding, J Liu, Z Zhang, J Guo, M Cheng, Y Wan, R Wang, Y Fang, Z Guan, ... Bioorganic Chemistry 101, 104023, 2020 | 28 | 2020 |
Recent advances in the medicinal chemistry of farnesoid X receptor Y Fang, L Hegazy, BN Finck, B Elgendy Journal of Medicinal Chemistry 64 (24), 17545-17571, 2021 | 27 | 2021 |
Fabrication of ultra-small nanocrystals by formation of hydrogen bonds: In vitro and in vivo evaluation L Tu, M Cheng, Y Sun, Y Fang, J Liu, W Liu, J Feng, Y Jin International Journal of Pharmaceutics 573, 118730, 2020 | 21 | 2020 |
Synthesis and biological evaluation of novel 2, 4-disubstituted quinazoline analogues as GPR119 agonists TAN Pham, Z Yang, Y Fang, J Luo, J Lee, H Park Bioorganic & medicinal chemistry 21 (5), 1349-1356, 2013 | 20 | 2013 |
Pristimerin attenuates cell proliferation of uveal melanoma cells by inhibiting insulin‐like growth factor‐1 receptor and its downstream pathways X Xie, S Xie, C Xie, Y Fang, Z Li, R Wang, W Jiang Journal of Cellular and Molecular Medicine 23 (11), 7545-7553, 2019 | 19 | 2019 |
Nitric oxide-donating derivatives of hederacolchiside A1: Synthesis and biological evaluation in vitro and in vivo as potential anticancer agents Y Fang, R Wang, M He, H Huang, Q Wang, Z Yang, Y Li, S Yang, Y Jin Bioorganic & Medicinal Chemistry Letters 27 (1), 98-101, 2017 | 19 | 2017 |
Design, synthesis, and biological evaluation of novel xanthone-alkylbenzylamine hybrids as multifunctional agents for the treatment of Alzheimer’s disease Z Zhang, J Guo, M Cheng, W Zhou, Y Wan, R Wang, Y Fang, Y Jin, J Liu, ... European Journal of Medicinal Chemistry 213, 113154, 2021 | 18 | 2021 |
Synthesis and biological evaluation of pyrimidine derivatives with diverse azabicyclic ether/amine as novel GPR119 agonist Z Yang, Y Fang, H Park Bioorganic & Medicinal Chemistry Letters 27 (11), 2515-2519, 2017 | 16 | 2017 |
Novel 5-nitropyrimidine derivatives bearing endo-azabicyclic alcohols/amines as potent GPR119 agonists Y Fang, Z Yang, S Gundeti, J Lee, H Park Bioorganic & Medicinal Chemistry 25 (1), 254-260, 2017 | 16 | 2017 |
New alkaloids with anti-inflammatory activities from Corydalis decumbens Q Wang, Z Li, Z Yang, Y Fang, H Ouyang, H Liao, Y Feng, S Yang Phytochemistry letters 18, 83-86, 2016 | 16 | 2016 |
Synthesis and biological evaluation of Hederacolchiside A1 derivatives as anticancer agents Y Fang, Z Yang, H Ouyang, R Wang, J Li, H Huang, Y Jin, Y Feng, S Yang Bioorganic & medicinal chemistry letters 26 (19), 4576-4579, 2016 | 16 | 2016 |
A multi-target directed ligands strategy for the treatment of Alzheimer's disease: Dimethyl fumarate plus Tranilast modified Dithiocarbate as AChE inhibitor and Nrf2 activator J Guo, M Cheng, P Liu, D Cao, J Luo, Y Wan, Y Fang, Y Jin, SS Xie, J Liu European Journal of Medicinal Chemistry 242, 114630, 2022 | 15 | 2022 |
Polymyxin B-inspired non-hemolytic tyrocidine A analogues with significantly enhanced activity against gram-negative bacteria: How cationicity impacts cell specificity and … J Zhu, C Hu, Z Zeng, X Deng, L Zeng, S Xie, Y Fang, Y Jin, V Alezra, ... European Journal of Medicinal Chemistry 221, 113488, 2021 | 15 | 2021 |
Nanocrystal-loaded micelles for the enhanced in vivo circulation of docetaxel M Cheng, Q Liu, T Gan, Y Fang, P Yue, Y Sun, Y Jin, J Feng, L Tu Molecules 26 (15), 4481, 2021 | 15 | 2021 |
Design and synthesis of novel senkyunolide analogues as neuroprotective agents Y Fang, R Wang, Q Wang, Y Sun, S Xie, Z Yang, M Li, Y Jin, S Yang Bioorganic & Medicinal Chemistry Letters 28 (4), 668-672, 2018 | 15 | 2018 |
Inhibitory activity of Cordyceps bassiana extract on LPS-induced inflammation in RAW 264.7 cells by suppressing NF-κB activation DH Yoon, C Han, Y Fang, S Gundeti, IS Han Lee, WO Song, KC Hwang, ... Natural Product Sciences 23 (3), 162-168, 2017 | 15 | 2017 |
Emerging role of nuclear receptors for the treatment of NAFLD and NASH RD Welch, C Billon, MK Losby, G Bedia-Diaz, Y Fang, A Avdagic, ... Metabolites 12 (3), 238, 2022 | 14 | 2022 |