Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries C Fernandez-Rozadilla, M Timofeeva, Z Chen, P Law, M Thomas, ... Nature genetics 55 (1), 89-99, 2023 | 62 | 2023 |
Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers: A mendelian randomization analysis J Yarmolinsky, V Díez-Obrero, TG Richardson, M Pigeyre, J Sjaarda, ... PLoS medicine 19 (2), e1003897, 2022 | 37 | 2022 |
Identifying putative susceptibility genes and evaluating their associations with somatic mutations in human cancers Z Chen, W Wen, A Beeghly-Fadiel, X Shu, V Díez-Obrero, J Long, J Bao, ... The American Journal of Human Genetics 105 (3), 477-492, 2019 | 35 | 2019 |
Colorectal cancer, sun exposure and dietary vitamin D and calcium intake in the MCC-Spain study X Vallès, MH Alonso, JF López-Caleya, V Díez-Obrero, T Dierssen-Sotos, ... Environment international 121, 428-434, 2018 | 31 | 2018 |
Genetic effects on transcriptome profiles in colon epithelium provide functional insights for genetic risk loci V Díez-Obrero, CH Dampier, F Moratalla-Navarro, M Devall, SJ Plummer, ... Cellular and molecular gastroenterology and hepatology 12 (1), 181-197, 2021 | 19 | 2021 |
Oncogenic features in histologically normal mucosa: novel insights into field effect from a Mega-Analysis of colorectal transcriptomes CH Dampier, M Devall, LT Jennelle, V Díez-Obrero, SJ Plummer, ... Clinical and Translational Gastroenterology 11 (7), e00210, 2020 | 17 | 2020 |
Transcriptome-wide association study for inflammatory bowel disease reveals novel candidate susceptibility genes in specific colon subsites and tissue categories V Díez-Obrero, F Moratalla-Navarro, G Ibáñez-Sanz, J Guardiola, ... Journal of Crohn's and Colitis 16 (2), 275-285, 2022 | 14 | 2022 |
Transcriptome-wide In Vitro Effects of Aspirin on Patient-derived Normal Colon Organoids MAM Devall, DA Drew, CH Dampier, SJ Plummer, S Eaton, J Bryant, ... Cancer Prevention Research 14 (12), 1089-1100, 2021 | 13 | 2021 |
Germline determinants of humoral immune response to HPV-16 protect against oropharyngeal cancer A Ferreiro-Iglesias, JD McKay, N Brenner, S Virani, C Lesseur, ... Nature communications 12 (1), 5945, 2021 | 13 | 2021 |
The 40S-LARP1 complex reprograms the cellular translatome upon mTOR inhibition to preserve the protein synthetic capacity P Fuentes, J Pelletier, C Martinez-Herráez, V Diez-Obrero, F Iannizzotto, ... Science Advances 7 (48), eabg9275, 2021 | 12 | 2021 |
COLONOMICS-integrative omics data of one hundred paired normal-tumoral samples from colon cancer patients A Díez-Villanueva, R Sanz-Pamplona, X Solé, D Cordero, M Crous-Bou, ... Scientific data 9 (1), 595, 2022 | 8 | 2022 |
Co‐occurrence of germline pathogenic variants for different hereditary cancer syndromes in patients with Lynch syndrome R Ferrer‐Avargues, MI Castillejo, E Dámaso, V Díez‐Obrero, N Garrigos, ... Cancer Communications 41 (3), 218-228, 2021 | 7 | 2021 |
Beyond GWAS of colorectal cancer: evidence of Interaction with alcohol consumption and putative causal variant for the 10q24. 2 region KM Jordahl, A Shcherbina, AE Kim, YR Su, Y Lin, J Wang, C Qu, ... Cancer Epidemiology, Biomarkers & Prevention 31 (5), 1077-1089, 2022 | 6 | 2022 |
Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids M Devall, CH Dampier, S Eaton, MW Ali, V Díez-Obrero, ... Oncotarget 12 (19), 1863, 2021 | 6 | 2021 |
Characterization of a novel POLD1 missense founder mutation in a Spanish population R Ferrer‐Avargues, V Díez‐Obrero, E Martín‐Tomás, E Hernández‐Illán, ... The Journal of Gene Medicine 19 (4), e2951, 2017 | 5 | 2017 |
Probing the diabetes and colorectal cancer relationship using gene–environment interaction analyses N Dimou, AE Kim, O Flanagan, N Murphy, V Diez-Obrero, A Shcherbina, ... British journal of cancer 129 (3), 511-520, 2023 | 3 | 2023 |
A genetic locus within the FMN1/GREM1 gene region interacts with body mass index in colorectal cancer risk EK Aglago, A Kim, Y Lin, C Qu, M Evangelou, Y Ren, J Morrison, ... Cancer research 83 (15), 2572-2583, 2023 | 3 | 2023 |
Genome-wide interaction analysis of genetic variants with menopausal hormone therapy for colorectal cancer risk Y Tian, AE Kim, SA Bien, Y Lin, C Qu, TA Harrison, R Carreras-Torres, ... Journal of the National Cancer Institute 114 (8), 1135-1148, 2022 | 2 | 2022 |
Genetically-proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers J Yarmolinsky, V Díez-Obrero, TG Richardson, M Pigeyre, J Sjaarda, ... medRxiv, 2021.03. 11.21252971, 2021 | 2 | 2021 |
Genome-wide interaction analysis of folate for colorectal cancer risk E Bouras, AE Kim, Y Lin, J Morrison, M Du, D Albanes, EL Barry, ... The American journal of clinical nutrition 118 (5), 881-891, 2023 | 1 | 2023 |