| Identification of thiourea-based inhibitors of the B-cell lymphoma 6 BTB domain via NMR-based fragment screening and computer-aided drug design H Cheng, BM Linhares, W Yu, MG Cardenas, Y Ai, W Jiang, A Winkler, ... Journal of medicinal chemistry 61 (17), 7573-7588, 2018 | 41 | 2018 |
| Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain S Shukla, W Ying, F Gray, Y Yao, ML Simes, Q Zhao, H Miao, HJ Cho, ... Nature chemical biology 17 (7), 784-793, 2021 | 34 | 2021 |
| Development of potent dimeric inhibitors of GAS41 YEATS domain D Listunov, BM Linhares, EG Kim, A Winkler, ML Simes, S Weaver, ... Cell Chemical Biology 28 (12), 1716-1727. e6, 2021 | 15 | 2021 |
| Molecular investigation of the tandem Tudor domain and plant homeodomain histone binding domains of the epigenetic regulator UHRF2 SM Ginnard, AE Winkler, C Mellado Fritz, T Bluhm, R Kemmer, M Gilliam, ... Proteins: Structure, Function, and Bioinformatics 90 (3), 835-847, 2022 | 5 | 2022 |
| MRG15 activates histone methyltransferase activity of ASH1L by recruiting it to the nucleosomes S Al-Harthi, H Li, A Winkler, K Szczepski, J Deng, J Grembecka, ... Structure 31 (10), 1200-1207. e5, 2023 | 1 | 2023 |
| Targeting the GAS41 YEATS domain in non-small cell lung cancer with novel small molecules A Winkler, D Listunov, B Linhares, J Ray, S Weaver, S Zolov, ... Cancer Research 84 (6_Supplement), 3239-3239, 2024 | | 2024 |
| GAS41 inhibitors and methods of use thereof A Winkler, B Linhares, D Listunov, J Grembecka, T Cierpicki, EG Kim US Patent 11,858,925, 2024 | | 2024 |
| Targeting Polycomb Repressive Complex 1 with small-molecule inhibitors as a potential therapeutic approach to combat leukemia ML Simes, Y Yao, SR Park, T Purohit, H Miao, X Zhang, W Ying, F Gray, ... Cancer Research 83 (7_Supplement), 6286-6286, 2023 | | 2023 |
| H3K9me3 binding analysis of the isolated PHD and TTD domains of UHRF2 I Miller, P Khuansanguan, S Ginnard, A Winkler, D Heyl, R Trievel The FASEB Journal 36, 2022 | | 2022 |
| Molecular investigation of the TTD and PHD histone binding domains of the epigenetic regulator UHRF2 BN Albaugh, S Ginnard, A Winkler, C Mellado Fritz, R Kemmer, T Bluhm, ... The FASEB Journal 36, 2022 | | 2022 |
| Molecular investigation of the TTD and PHD histone binding domains of the epigenetic regulator UHRF2. SM Ginnard, AE Winkler, CM Fritz, T Bluhm, R Kemmer, M Gilliam, ... Proteins, 2021 | | 2021 |
| Molecular Characterization of UHRF1 and UHRF2 A Winkler, B Albaugh The FASEB Journal 31, 755.11-755.11, 2017 | | 2017 |
| Effect of a bulky substituent on the stereoselectivity of a reaction leading to acylpyrrolidines A Winkler, MC Milletti ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 248, 2014 | | 2014 |
| Substituent effects in a Lewis acid catalyzed aza-Cope Mannich tandem reaction A Winkler, MC Milletti ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 244, 2012 | | 2012 |
Brian M. LinharesBiohaven Pharmaceuticals, Inc.Verified email at biohavenpharma.com
