Cardiomyocyte contractile impairment in heart failure results from reduced BAG3-mediated sarcomeric protein turnover TG Martin, VD Myers, P Dubey, S Dubey, E Perez, CS Moravec, MS Willis, ... Nature communications 12 (1), 2942, 2021 | 74 | 2021 |
Diabetes with heart failure increases methylglyoxal modifications in the sarcomere, which inhibit function M Papadaki, RJ Holewinski, SB Previs, TG Martin, MJ Stachowski, A Li, ... JCI insight 3 (20), 2018 | 57 | 2018 |
Under construction: The dynamic assembly, maintenance, and degradation of the cardiac sarcomere TG Martin, JA Kirk Journal of molecular and cellular cardiology 148, 89-102, 2020 | 54 | 2020 |
Regression of cardiac hypertrophy in health and disease: mechanisms and therapeutic potential TG Martin, MA Juarros, LA Leinwand Nature Reviews Cardiology 20 (5), 347-363, 2023 | 32 | 2023 |
BAG3 expression and sarcomere localization in the human heart are linked to HSF-1 and are differentially affected by sex and disease TG Martin, S Tawfik, CS Moravec, TR Pak, JA Kirk American Journal of Physiology-Heart and Circulatory Physiology 320 (6 …, 2021 | 22 | 2021 |
Pharmacological inhibition of BAG3‐HSP70 with the proposed cancer therapeutic JG‐98 is toxic for cardiomyocytes TG Martin, CE Delligatti, NA Muntu, MJ Stachowski‐Doll, JA Kirk Journal of cellular biochemistry 123 (1), 128-141, 2022 | 14 | 2022 |
Epidermal growth factor receptor-dependent maintenance of cardiac contractility S Guo, AD Okyere, E McEachern, JL Strong, RL Carter, VC Patwa, ... Cardiovascular Research 118 (5), 1276-1288, 2022 | 13 | 2022 |
GSK-3β localizes to the cardiac Z-disc to maintain length dependent activation MJ Stachowski-Doll, M Papadaki, TG Martin, W Ma, HM Gong, S Shao, ... Circulation research 130 (6), 871-886, 2022 | 12 | 2022 |
Deletion of cardiac polycystin 2/PC2 results in increased SR calcium release and blunted adrenergic reserve E DiNello, E Bovo, P Thuo, TG Martin, JA Kirk, AV Zima, Q Cao, IY Kuo American Journal of Physiology-Heart and Circulatory Physiology 319 (5 …, 2020 | 10 | 2020 |
Bag3 Regulates Mitochondrial Function and the Inflammasome Through Canonical and Noncanonical Pathways in the Heart JF Wang, D Tomar, TG Martin, S Dubey, PK Dubey, J Song, ... Basic to Translational Science 8 (7), 820-839, 2023 | 5 | 2023 |
Utility of the burmese Python as a model for studying plasticity of extreme physiological systems Y Tan, TG Martin, BC Harrison, LA Leinwand Journal of Muscle Research and Cell Motility 44 (2), 95-106, 2023 | 4 | 2023 |
Assessment of Autophagy Markers Suggests Increased Activity Following LVAD Therapy TG Martin, MA Juarros, JC Cleveland Jr, MR Bristow, AV Ambardekar, ... Basic to Translational Science 8 (9), 1043-1056, 2023 | 3 | 2023 |
BAG3: nature’s quintessential multi-functional protein functions as a ubiquitous intra-cellular glue CM Brenner, M Choudhary, MG McCormick, D Cheung, GP Landesberg, ... Cells 12 (6), 937, 2023 | 3 | 2023 |
HDAC Inhibition Regulates Cardiac Function by Increasing Myofilament Calcium Sensitivity and Decreasing Diastolic Tension DM Eaton, TG Martin, M Kasa, N Djalinac, S Ljubojevic-Holzer, ... Pharmaceutics 14 (7), 1509, 2022 | 3 | 2022 |
Peptidyl arginine deiminase inhibition alleviates angiotensin II-induced fibrosis T Ijichi, N Sundararaman, TG Martin, R Pandey, E Koronyo, JA Kirk, ... American Journal of Translational Research 15 (7), 4558, 2023 | 1 | 2023 |
Sweet and umami receptors are expressed in the heart and regulate contractility M Papadaki, SO Valencia, M Door, T Martin, MJ Stachowski, C Delligatti, ... Biophysical Journal 121 (3), 514a, 2022 | 1 | 2022 |
HDAC inhibition regulates cardiac function via myofilament acetylation DM Eaton, TG Martin, M Kasa, N Djalinac, JP Johnson, E Kolesnik, ... Circulation 144 (Suppl_1), A10254-A10254, 2021 | 1 | 2021 |
BAG3-dependent autophagy maintains sarcomere function in cardiomyocytes TG Martin, VD Myers, P Dubey, S Dubey, E Perez, CS Morevec, MS Willis, ... BioRxiv, 2020.04. 10.022319, 2020 | 1 | 2020 |
BAG3 localizes to mitochondria in cardiac fibroblasts and regulates mitophagy TG Martin, LA Sherer, JA Kirk American Journal of Physiology-Heart and Circulatory Physiology 326 (5 …, 2024 | | 2024 |
BAG3 differentially responds to acute and chronic stress via a post-transcriptional mechanism LA Sherer, T Martin, M Door, JA Kirk Biophysical Journal 123 (3), 123a, 2024 | | 2024 |