IDH mutation impairs histone demethylation and results in a block to cell differentiation C Lu, PS Ward, GS Kapoor, D Rohle, S Turcan, O Abdel-Wahab, ... Nature 483 (7390), 474-478, 2012 | 2150 | 2012 |
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype S Turcan, D Rohle, A Goenka, LA Walsh, F Fang, E Yilmaz, C Campos, ... Nature 483 (7390), 479-483, 2012 | 2118 | 2012 |
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells D Rohle, J Popovici-Muller, N Palaskas, S Turcan, C Grommes, ... Science 340 (6132), 626-630, 2013 | 1271 | 2013 |
Glutamatergic synaptic input to glioma cells drives brain tumour progression V Venkataramani, DI Tanev, C Strahle, A Studier-Fischer, L Fankhauser, ... Nature 573 (7775), 532-538, 2019 | 737 | 2019 |
The mutational landscape of adenoid cystic carcinoma AS Ho, K Kannan, DM Roy, LGT Morris, I Ganly, N Katabi, D Ramaswami, ... Nature genetics 45 (7), 791-798, 2013 | 471 | 2013 |
BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1 M Tönjes, S Barbus, YJ Park, W Wang, M Schlotter, AM Lindroth, ... Nature medicine 19 (7), 901-908, 2013 | 467 | 2013 |
Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation LGT Morris, AM Kaufman, Y Gong, D Ramaswami, LA Walsh, Ş Turcan, ... Nature genetics 45 (3), 253-261, 2013 | 435 | 2013 |
Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate L Bunse, S Pusch, T Bunse, F Sahm, K Sanghvi, M Friedrich, D Alansary, ... Nature medicine 24 (8), 1192-1203, 2018 | 426 | 2018 |
Breast cancer methylomes establish an epigenomic foundation for metastasis F Fang, S Turcan, A Rimner, A Kaufman, D Giri, LGT Morris, R Shen, ... Science translational medicine 3 (75), 75ra25-75ra25, 2011 | 347 | 2011 |
Integrated genomic characterization of IDH1-mutant glioma malignant progression H Bai, AS Harmancı, EZ Erson-Omay, J Li, S Coşkun, M Simon, ... Nature genetics 48 (1), 59-66, 2016 | 310 | 2016 |
Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine S Turcan, AWM Fabius, A Borodovsky, A Pedraza, C Brennan, J Huse, ... Oncotarget 4 (10), 1729, 2013 | 281 | 2013 |
5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft A Borodovsky, V Salmasi, S Turcan, AWM Fabius, GS Baia, CG Eberhart, ... Oncotarget 4 (10), 1737, 2013 | 196 | 2013 |
Mutant-IDH1-dependent chromatin state reprogramming, reversibility, and persistence S Turcan, V Makarov, J Taranda, Y Wang, AWM Fabius, W Wu, Y Zheng, ... Nature genetics 50 (1), 62-72, 2018 | 170 | 2018 |
Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins Y Gong, TI Zack, LGT Morris, K Lin, E Hukkelhoven, R Raheja, IL Tan, ... Nature genetics 46 (6), 588-594, 2014 | 169 | 2014 |
The α10 nicotinic acetylcholine receptor subunit is required for normal synaptic function and integrity of the olivocochlear system DE Vetter, E Katz, SF Maison, J Taranda, S Turcan, J Ballestero, ... Proceedings of the National Academy of Sciences 104 (51), 20594-20599, 2007 | 145 | 2007 |
An integrated systems biology approach identifies TRIM25 as a key determinant of breast cancer metastasis LA Walsh, MJ Alvarez, EY Sabio, M Reyngold, V Makarov, S Mukherjee, ... Cell reports 20 (7), 1623-1640, 2017 | 99 | 2017 |
Transcriptional diversity of long-term glioblastoma survivors NK Gerber, A Goenka, S Turcan, M Reyngold, V Makarov, K Kannan, ... Neuro-oncology 16 (9), 1186-1195, 2014 | 98 | 2014 |
Targeting therapeutic vulnerabilities with PARP inhibition and radiation in IDH-mutant gliomas and cholangiocarcinomas Y Wang, AT Wild, S Turcan, WH Wu, C Sigel, DS Klimstra, X Ma, Y Gong, ... Science Advances 6 (17), eaaz3221, 2020 | 86 | 2020 |
Origin of gliomas D Cahill, S Turcan Seminars in neurology 38 (01), 005-010, 2018 | 75 | 2018 |
Epigenetic therapy: use of agents targeting deacetylation and methylation in cancer management AS Ho, S Turcan, TA Chan OncoTargets and therapy, 223-232, 2013 | 61 | 2013 |