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Matthew Cyr
Matthew Cyr
Graduate Student, The Scripps Research Institute
Verified email at scripps.edu
Title
Cited by
Cited by
Year
Crystal structure of full-length Zika virus NS5 protein reveals a conformation similar to Japanese encephalitis virus NS5
AK Upadhyay, M Cyr, K Longenecker, R Tripathi, C Sun, DJ Kempf
Acta Crystallographica Section F: Structural Biology Communications 73 (3 …, 2017
992017
A widely-applicable high-throughput cellular thermal shift assay (CETSA) using split Nano Luciferase
NJ Martinez, RR Asawa, MG Cyr, A Zakharov, DJ Urban, JS Roth, ...
Scientific reports 8 (1), 9472, 2018
882018
Structure-based engineering of irreversible inhibitors against histone lysine demethylase KDM5A
JR Horton, CB Woodcock, Q Chen, X Liu, X Zhang, J Shanks, G Rai, ...
Journal of medicinal chemistry 61 (23), 10588-10601, 2018
322018
Siglec-6 is a target for chimeric antigen receptor T-cell treatment of chronic lymphocytic leukemia
D Kovalovsky, JH Yoon, MG Cyr, S Simon, E Voynova, C Rader, ...
Leukemia 35 (9), 2581-2591, 2021
172021
Siglec-6 on chronic lymphocytic leukemia cells is a target for post-allogeneic hematopoietic stem cell transplantation antibodies
J Chang, H Peng, BC Shaffer, S Baskar, IC Wecken, MG Cyr, GJ Martinez, ...
Cancer immunology research 6 (9), 1008-1013, 2018
142018
Patient-derived Siglec-6-targeting antibodies engineered for T-cell recruitment have potential therapeutic utility in chronic lymphocytic leukemia
MG Cyr, M Mhibik, J Qi, H Peng, J Chang, EM Gaglione, D Eik, J Herrick, ...
Journal for Immunotherapy of Cancer 10 (11), 2022
52022
Siglec-6 as a therapeutic target for cell migration and adhesion in chronic lymphocytic leukemia
J Nunes, R Tafesse, C Mao, M Purcell, X Mo, L Zhang, M Long, MG Cyr, ...
Nature Communications 15 (1), 5180, 2024
2024
Concerted Antibody and Antigen Discovery by Differential Whole-cell Phage Display Selections and Multi-omic Target Deconvolution
MG Cyr, HD Wilson, AL Spierling, J Chang, H Peng, P Steinberger, ...
Journal of Molecular Biology 435 (10), 168085, 2023
2023
Exploring the therapeutic potential of a novel Siglec-6 targeted bispecific antibody to selectively kill leukemia cells
J Nunes, C Mao, M Purcell, E Perry, L Zhang, X Mo, M Cyr, M Long, J Byrd, ...
Cancer Research 83 (7_Supplement), 2966-2966, 2023
2023
Antibody-Driven Target Discovery and Antibody Engineering for Cancer Treatment
MG Cyr
The Scripps Research Institute, 2022
2022
Systematic target deconvolution: Are we there yet?
G Zahoranszky-Kohalmi, R Guha, M Cyr, C Danchik, S Fang, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019
2019
Riding the waves of PPI-network perturbations to predict phenotypic assay outcome
G Zahoranszky-Kohalmi, R Guha, M Cyr, M Henderson, S Fang, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018
2018
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