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Michael Hornsby
Michael Hornsby
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Year
Lipocalin-2 resistance confers an advantage to Salmonella enterica serotype Typhimurium for growth and survival in the inflamed intestine
M Raffatellu, MD George, Y Akiyama, MJ Hornsby, SP Nuccio, TA Paixao, ...
Cell host & microbe 5 (5), 476-486, 2009
5662009
Redox-based reagents for chemoselective methionine bioconjugation
S Lin, X Yang, S Jia, AM Weeks, M Hornsby, PS Lee, RV Nichiporuk, ...
Science 355 (6325), 597-602, 2017
4352017
A high through-put platform for recombinant antibodies to folded proteins
M Hornsby, M Paduch, S Miersch, A Sääf, T Matsuguchi, B Lee, ...
Molecular & Cellular Proteomics 14 (10), 2833-2847, 2015
1142015
Identification of selective, nonpeptidic nitrile inhibitors of cathepsin S using the substrate activity screening method
AW Patterson, WJL Wood, M Hornsby, S Lesley, G Spraggon, JA Ellman
Journal of medicinal chemistry 49 (21), 6298-6307, 2006
1112006
Identification of coumarin derivatives as a novel class of allosteric MEK1 inhibitors
S Han, V Zhou, S Pan, Y Liu, M Hornsby, D McMullan, HE Klock, ...
Bioorganic & medicinal chemistry letters 15 (24), 5467-5473, 2005
1042005
Helicobacter pylori induces an antimicrobial response in rhesus macaques in a cag pathogenicity island-dependent manner
MJ Hornsby, JL Huff, RJ Kays, DR Canfield, CL Bevins, JV Solnick
Gastroenterology 134 (4), 1049-1057, 2008
1022008
Crystal structure of human Pus10, a novel pseudouridine synthase
CJ McCleverty, M Hornsby, G Spraggon, A Kreusch
Journal of molecular biology 373 (5), 1243-1254, 2007
942007
An improved single-chain Fab platform for efficient display and recombinant expression
JT Koerber, MJ Hornsby, JA Wells
Journal of molecular biology 427 (2), 576-586, 2015
692015
Crystal structure of the global regulatory protein CsrA from Pseudomonas putida at 2.05 Å resolution reveals a new fold
C Rife, R Schwarzenbacher, D McMullan, P Abdubek, E Ambing, ...
Proteins: Structure, Function, and Bioinformatics 61 (2), 449-453, 2005
632005
Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations
G Spraggon, M Hornsby, A Shipway, DC Tully, B Bursulaya, H Danahay, ...
Protein Science 18 (5), 1081-1094, 2009
492009
Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies
SB Pollock, A Hu, Y Mou, AJ Martinko, O Julien, M Hornsby, L Ploder, ...
Proceedings of the National Academy of Sciences 115 (11), 2836-2841, 2018
482018
Three essential resources to improve differential scanning fluorimetry (DSF) experiments
T Wu, J Yu, Z Gale-Day, A Woo, A Suresh, M Hornsby, JE Gestwicki
BioRxiv, 2020.03. 22.002543, 2020
442020
Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 2.06 Å resolution
Q Xu, R Schwarzenbacher, S Sri Krishna, D McMullan, S Agarwalla, ...
Proteins: Structure, Function, and Bioinformatics 64 (3), 808-813, 2006
432006
Scalable high throughput selection from phage-displayed synthetic antibody libraries
S Miersch, Z Li, R Hanna, ME McLaughlin, M Hornsby, T Matsuguchi, ...
JoVE (Journal of Visualized Experiments), e51492, 2015
422015
Characterization and optimization of selective, nonpeptidic inhibitors of cathepsin S with an unprecedented binding mode
H Inagaki, H Tsuruoka, M Hornsby, SA Lesley, G Spraggon, JA Ellman
Journal of medicinal chemistry 50 (11), 2693-2699, 2007
392007
Synthesis and SAR of arylaminoethyl amides as noncovalent inhibitors of cathepsin S: P3 cyclic ethers
DC Tully, H Liu, AK Chatterjee, PB Alper, R Epple, JA Williams, ...
Bioorganic & medicinal chemistry letters 16 (19), 5112-5117, 2006
382006
Determination of equilibrium dissociation constants for recombinant antibodies by high-throughput affinity electrophoresis
Y Pan, EK Sackmann, K Wypisniak, M Hornsby, SS Datwani, AE Herr
Scientific Reports 6 (1), 39774, 2016
282016
Biochemical basis for distinct roles of the heterochromatin proteins Swi6 and Chp2
RS Isaac, S Sanulli, R Tibble, M Hornsby, M Ravalin, CS Craik, JD Gross, ...
Journal of molecular biology 429 (23), 3666-3677, 2017
272017
Evidence of convergent evolution in humans and macaques supports an adaptive role for copy number variation of the β-defensin-2 gene
B Ottolini, MJ Hornsby, R Abujaber, JAL MacArthur, RM Badge, ...
Genome biology and evolution 6 (11), 3025-3038, 2014
252014
Crystal structure of S‐adenosylmethionine:tRNA ribosyltransferase‐isomerase (QueA) from Thermotoga maritima at 2.0 Å resolution reveals a new fold
I Mathews, R Schwarzenbacher, D McMullan, P Abdubek, E Ambing, ...
Proteins: Structure, Function, and Bioinformatics 59 (4), 869-874, 2005
212005
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