Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 730 | 2021 |
Impact of a five-dimensional framework on R&D productivity at AstraZeneca P Morgan, DG Brown, S Lennard, MJ Anderton, JC Barrett, U Eriksson, ... Nature reviews Drug discovery 17 (3), 167-181, 2018 | 380 | 2018 |
Screening β-arrestin recruitment for the identification of natural ligands for orphan G-protein–coupled receptors C Southern, JM Cook, Z Neetoo-Isseljee, DL Taylor, CA Kettleborough, ... Journal of biomolecular screening 18 (5), 599-609, 2013 | 208 | 2013 |
Evaporation, seepage and water quality management in storage dams: a review of research methods I Craig, V Aravinthan, C Baillie, A Beswick, G Barnes, R Bradbury, ... Environmental Health 7 (3), 84-97, 2007 | 59 | 2007 |
Effects of a range of β2 adrenoceptor agonists on changes in intracellular cyclic AMP and on cyclic AMP driven gene expression in cultured human airway smooth … MGH Scott, C Swan, TM Jobson, S Rees, IP Hall British journal of pharmacology 128 (3), 721-729, 1999 | 40 | 1999 |
Towards a hit for every target S Rees, P Gribbon, K Birmingham, WP Janzen, G Pairaudeau Nature Reviews Drug Discovery 15 (1), 1-2, 2016 | 25 | 2016 |
The BlueScreen-384 assay as an indicator of genotoxic hazard potential in early-stage drug discovery K Simpson, N Bevan, P Hastwell, P Eidam, P Shah, E Gogo, S Rees, ... Journal of biomolecular screening 18 (4), 441-452, 2013 | 25 | 2013 |
A novel and efficient method for the stable expression of heteromeric ion channels in mammalian cells. E Kawashima, D Estoppey, C Virginio, D Fahmi, S Rees, A Surprenant, ... Receptors & channels 5 (2), 53-60, 1998 | 24 | 1998 |
Simultaneous inhibition of DNA-PK and Polϴ improves integration efficiency and precision of genome editing S Wimberger, N Akrap, M Firth, J Brengdahl, S Engberg, MK Schwinn, ... Nature Communications 14 (1), 4761, 2023 | 16 | 2023 |
Mammalian expression of transmembrane receptors for pharmaceutical applications. AD Rhodes, N Bevan, K Patel, M Lee, S Rees Biochemical Society Transactions 26 (4), 699-704, 1998 | 13 | 1998 |
Heat inactivation of clinical COVID-19 samples on an industrial scale for low risk and efficient high-throughput qRT-PCR diagnostic testing O Delpuech, JA Douthwaite, T Hill, D Niranjan, NT Malintan, H Duvoisin, ... Scientific Reports 12 (1), 2883, 2022 | 12 | 2022 |
Feasibility and efficacy of mass testing for SARS-CoV-2 in a UK university using swab pooling and PCR B Warne, J Enright, M Metaxaki, S Fuller, RJ Samworth, G Weale, ... | 7 | 2021 |
The promise of open innovation in drug discovery: an industry perspective S Rees Future Medicinal Chemistry 7 (14), 1835-1838, 2015 | 7 | 2015 |
Development and evaluation of a prototype precision spot spray system using image analysis to target Guinea Grass in sugarcane SJ Rees, CL McCarthy, CP Baillie, XP Burgos-Artizzu, MT Dunn Australian Journal of Multi-disciplinary Engineering 8 (2), 97-106, 2011 | 6 | 2011 |
A Combined Human in Silico and CRISPR/Cas9-Mediated in Vivo Zebrafish Based Approach to Provide Phenotypic Data for Supporting Early Target Validation MJ Winter, Y Ono, JS Ball, A Walentinsson, E Michaelsson, A Tochwin, ... Frontiers in Pharmacology 13, 827686, 2022 | 5 | 2022 |
Evaluating commercially available precision weed spraying technology for detecting weeds in sugarcane farming systems C Baille, E Fillols, C McCarthy, S Rees, T Staier ASSCT, 2013 | 3 | 2013 |
Tips G Milligan, F Marshall, S Rees | 3 | 1997 |
Improving the efficiency and effectiveness of an industrial SARS-CoV-2 diagnostic facility JA Douthwaite, CA Brown, JR Ferdinand, R Sharma, J Elliott, MA Taylor, ... Scientific Reports 12 (1), 3114, 2022 | 2 | 2022 |
An iteratively optimised process for improving the efficiency and effectiveness of an industrial SARS-CoV-2 diagnostic facility JA Douthwaite, CA Brown, JR Ferdinand, R Sharma, J Elliott, M Taylor, ... | 1 | 2021 |
Incorporation of the GADD45-GFP greenscreen HC assay into pre-clinical drug development screening to reduce compound attrition PW Hastwell, BZ Dilmamode, BL Powney, AJ Brown, JS Harvey, ... Mutagenesis 24 (6), 549-549, 2009 | 1 | 2009 |