Interrelation of oxidative stress and inflammation in neurodegenerative disease: role of TNF R Fischer, O Maier Oxidative medicine and cellular longevity 2015, 2015 | 697 | 2015 |
Selective targeting of TNF receptors as a novel therapeutic approach R Fischer, RE Kontermann, K Pfizenmaier Frontiers in Cell and Developmental Biology 8, 2020 | 165 | 2020 |
Essential protective role of tumor necrosis factor receptor 2 in neurodegeneration Y Dong, R Fischer, PJW Naudé, O Maier, C Nyakas, M Duffey, ... Proceedings of the National Academy of Sciences 113 (43), 12304-12309, 2016 | 163 | 2016 |
Role of caspases in cytokine-induced barrier breakdown in human brain endothelial cells MA Lopez-Ramirez, R Fischer, CC Torres-Badillo, HA Davies, K Logan, ... The Journal of Immunology 189 (6), 3130-3139, 2012 | 137 | 2012 |
A TNF receptor 2 selective agonist rescues human neurons from oxidative stress-induced cell death R Fischer, O Maier, M Siegemund, H Wajant, P Scheurich, K Pfizenmaier PLoS One 6 (11), e27621, 2011 | 129 | 2011 |
Astrocyte‐specific activation of TNFR2 promotes oligodendrocyte maturation by secretion of leukemia inhibitory factor R Fischer, H Wajant, R Kontermann, K Pfizenmaier, O Maier Glia 62 (2), 272-283, 2014 | 118 | 2014 |
TNF-Receptor-1 inhibition reduces liver steatosis, hepatocellular injury and fibrosis in NAFLD mice F Wandrer, S Liebig, S Marhenke, A Vogel, K John, MP Manns, A Teufel, ... Cell Death & Disease 11 (3), 1-9, 2020 | 115 | 2020 |
Inflammation and Oxidative Stress in Multiple Sclerosis: Consequences for Therapy Development V Pegoretti, KA Swanson, JR Bethea, L Probert, ULM Eisel, R Fischer Oxidative Medicine and Cellular Longevity 2020, 2020 | 111 | 2020 |
Targeting sTNF/TNFR1 signaling as a new therapeutic strategy R Fischer, R Kontermann, O Maier Antibodies 4 (1), 48-70, 2015 | 109 | 2015 |
Antibody-mediated inhibition of TNFR1 attenuates disease in a mouse model of multiple sclerosis SK Williams, O Maier, R Fischer, R Fairless, S Hochmeister, A Stojic, ... PloS one 9 (2), e90117, 2014 | 75 | 2014 |
TNF receptor 2 protects oligodendrocyte progenitor cells against oxidative stress O Maier, R Fischer, C Agresti, K Pfizenmaier Biochemical and biophysical research communications 440 (2), 336-341, 2013 | 71 | 2013 |
Development of a mouse pain scale using sub-second behavioral mapping and statistical modeling I Abdus-Saboor, NT Fried, M Lay, J Burdge, K Swanson, R Fischer, ... Cell reports 28 (6), 1623-1634. e4, 2019 | 69 | 2019 |
Neuropathic pain in multiple sclerosis—current therapeutic intervention and future treatment perspectives KL Murphy, JR Bethea, R Fischer Multiple Sclerosis: Perspectives in Treatment and Pathogenesis [Internet], 2017 | 66 | 2017 |
TNFR2 promotes Treg-mediated recovery from neuropathic pain across sexes R Fischer, M Sendetski, T del Rivero, GF Martinez, V Bracchi-Ricard, ... Proceedings of the National Academy of Sciences 116 (34), 17045-17050, 2019 | 53 | 2019 |
Soluble TNFα signaling within the spinal cord contributes to the development of autonomic dysreflexia and ensuing vascular and immune dysfunction after spinal cord injury E Mironets, P Osei-Owusu, V Bracchi-Ricard, R Fischer, EA Owens, ... Journal of Neuroscience 38 (17), 4146-4162, 2018 | 53 | 2018 |
Anti-TNFR1 targeting in humanized mice ameliorates disease in a model of multiple sclerosis SK Williams, R Fairless, O Maier, PC Liermann, K Pichi, R Fischer, ... Scientific reports 8 (1), 13628, 2018 | 51 | 2018 |
Ligand-induced internalization of TNF receptor 2 mediated by a di-leucin motif is dispensable for activation of the NFκB pathway R Fischer, O Maier, M Naumer, A Krippner-Heidenreich, P Scheurich, ... Cellular signalling 23 (1), 161-170, 2011 | 47 | 2011 |
Selective activation of tumor necrosis factor receptor II induces antiinflammatory responses and alleviates experimental arthritis R Fischer, M Proske, M Duffey, H Stangl, GF Martinez, N Peters, A Kraske, ... Arthritis & Rheumatology 70 (5), 722-735, 2018 | 46 | 2018 |
Novel strategies to mimic transmembrane tumor necrosis factor-dependent activation of tumor necrosis factor receptor 2 R Fischer, J Marsal, C Guttà, SA Eisler, N Peters, JR Bethea, ... Scientific reports 7 (1), 6607, 2017 | 45 | 2017 |
Tumor necrosis factor receptor 1 inhibition is therapeutic for neuropathic pain in males but not in females T del Rivero, R Fischer, F Yang, KA Swanson, JR Bethea Pain 160 (4), 922-931, 2019 | 40 | 2019 |