Chun Wei Yap
Chun Wei Yap
National Healthcare Group
在 nhg.com.sg 的电子邮件经过验证
标题
引用次数
引用次数
年份
PaDELdescriptor: An open source software to calculate molecular descriptors and fingerprints
CW Yap
Journal of computational chemistry 32 (7), 1466-1474, 2011
11642011
Prediction of P-glycoprotein substrates by a support vector machine approach
Y Xue, CW Yap, LZ Sun, ZW Cao, JF Wang, YZ Chen
Journal of chemical information and computer sciences 44 (4), 1497-1505, 2004
2102004
Effect of molecular descriptor feature selection in support vector machine classification of pharmacokinetic and toxicological properties of chemical agents
Y Xue, ZR Li, CW Yap, LZ Sun, X Chen, YZ Chen
Journal of chemical information and computer sciences 44 (5), 1630-1638, 2004
1852004
Prediction of cytochrome P450 3A4, 2D6, and 2C9 inhibitors and substrates by using support vector machines
CW Yap, YZ Chen
Journal of chemical information and modeling 45 (4), 982-992, 2005
1802005
Therapeutic targets: progress of their exploration and investigation of their characteristics
CJ Zheng, LY Han, CW Yap, ZL Ji, ZW Cao, YZ Chen
Pharmacological reviews 58 (2), 259-279, 2006
1792006
Anticancer activity of thymoquinone in breast cancer cells: possible involvement of PPAR-γ pathway
CC Woo, SY Loo, V Gee, CW Yap, G Sethi, AP Kumar, KH Benny Tan
Biochemical pharmacology 82 (5), 464-475, 2011
1752011
Effect of selection of molecular descriptors on the prediction of blood-brain barrier penetrating and nonpenetrating agents by statistical learning methods
H Li, CW Yap, CY Ung, Y Xue, ZW Cao, YZ Chen
Journal of chemical information and modeling 45 (5), 1376-1384, 2005
1512005
QSAR Modeling is not “Push a Button and Find a Correlation”: A Case Study of Toxicity of (Benzo) triazoles on Algae
P Gramatica, S Cassani, PP Roy, S Kovarich, CW Yap, E Papa
Molecular Informatics 31 (1112), 817-835, 2012
1102012
Isorhamnetin Inhibits Proliferation and Invasion and Induces Apoptosis through the Modulation of Peroxisome Proliferator-activated Receptor γ Activation Pathway in Gastric Cancer
L Ramachandran, KA Manu, MK Shanmugam, F Li, KS Siveen, S Vali, ...
Journal of Biological Chemistry 287 (45), 38028-38040, 2012
892012
Prediction of genotoxicity of chemical compounds by statistical learning methods
H Li, CY Ung, CW Yap, Y Xue, ZR Li, ZW Cao, YZ Chen
Chemical research in toxicology 18 (6), 1071-1080, 2005
882005
Prediction of torsade-causing potential of drugs by support vector machine approach
CW Yap, CZ Cai, Y Xue, YZ Chen
Toxicological Sciences 79 (1), 170-177, 2004
882004
In Silico Prediction of Pregnane X Receptor Activators by Machine Learning Approache
CY Ung, H Li, CW Yap, YZ Chen
Molecular pharmacology 71 (1), 158-168, 2007
832007
Formulation development of transdermal dosage forms: Quantitative structure-activity relationship model for predicting activities of terpenes that enhance drug penetration …
L Kang, CW Yap, PFC Lim, YZ Chen, PC Ho, YW Chan, GP Wong, ...
Journal of controlled release 120 (3), 211-219, 2007
822007
Classification of a diverse set of tetrahymena pyriformis toxicity chemical compounds from molecular descriptors by statistical learning methods
Y Xue, H Li, CY Ung, CW Yap, YZ Chen
Chemical research in toxicology 19 (8), 1030-1039, 2006
802006
MODEL—molecular descriptor lab: A webbased server for computing structural and physicochemical features of compounds
ZR Li, LY Han, Y Xue, CW Yap, H Li, L Jiang, YZ Chen
Biotechnology and bioengineering 97 (2), 389-396, 2007
792007
Progress and problems in the exploration of therapeutic targets
C Zheng, L Han, CW Yap, B Xie, Y Chen
Drug discovery today 11 (9), 412-420, 2006
792006
Machine learning approaches for predicting compounds that interact with therapeutic and ADMET related proteins
H Li, CW Yap, CY Ung, Y Xue, ZR Li, LY Han, HH Lin, YZ Chen
Journal of pharmaceutical sciences 96 (11), 2838-2860, 2007
782007
Current Modeling Methods Used in QSAR/QSPR
LC Yee, YC Wei
Statistical Modelling of Molecular Descriptors in QSAR/QSPR, 1-31, 2012
672012
Quantitative structure-pharmacokinetic relationships for drug clearance by using statistical learning methods
CW Yap, ZR Li, YZ Chen
Journal of Molecular Graphics and Modelling 24 (5), 383-395, 2006
672006
Drug Adverse Reaction Target Database (DART): proteins related to adverse drug reactions
ZL Ji, LY Han, CW Yap, LZ Sun, X Chen, YZ Chen
Drug safety 26 (10), 685-690, 2003
672003
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