Targeting the main protease of SARS‐CoV‐2: from the establishment of high throughput screening to the design of tailored inhibitors J Breidenbach, C Lemke, T Pillaiyar, L Schäkel, G Al Hamwi, M Diett, ... Angewandte Chemie International Edition 60 (18), 10423-10429, 2021 | 111 | 2021 |
Nucleotide analog ARL67156 as a lead structure for the development of CD39 and dual CD39/CD73 ectonucleotidase inhibitors L Schäkel, CC Schmies, RM Idris, X Luo, SY Lee, V Lopez, S Mirza, ... Frontiers in Pharmacology 11, 1294, 2020 | 30 | 2020 |
Protein kinase inhibitor ceritinib blocks ectonucleotidase CD39–a promising target for cancer immunotherapy L Schäkel, S Mirza, R Winzer, V Lopez, R Idris, H Al-Hroub, J Pelletier, ... Journal for Immunotherapy of Cancer 10 (8), 2022 | 17 | 2022 |
Recombinant expression of ecto-nucleotide pyrophosphatase/phosphodiesterase 4 (NPP4) and development of a luminescence-based assay to identify inhibitors V Lopez, SY Lee, H Stephan, CE Müller Analytical biochemistry 603, 113774, 2020 | 14 | 2020 |
Sulfated polysaccharides from macroalgae are potent dual inhibitors of human ATP-hydrolyzing ectonucleotidases NPP1 and CD39 V Lopez, L Schäkel, HJM Schuh, MS Schmidt, S Mirza, C Renn, J Pelletier, ... Marine drugs 19 (2), 51, 2021 | 9 | 2021 |
Heparins are potent inhibitors of ectonucleotide pyrophosphatase/phosphodiesterase-1 (NPP1)-a promising target for the immunotherapy of cancer V Lopez, HJ Schuh, S Mirza, V Vaaßen, MS Schmidt, K Sylvester, RM Idris, ... Frontiers in Immunology 14, 1173634, 2023 | 2 | 2023 |
Identification and pharmacological characterization of nucleotide pyrophosphatase/phosphodiesterase-1 (NPP1) and-4 (NPP4) inhibitors V Lopez Universitäts-und Landesbibliothek Bonn, 2022 | 2 | 2022 |
Die Hauptprotease von SARS‐CoV‐2 als Zielstruktur: Von der Etablierung eines Hochdurchsatz‐Screenings zum Design maßgeschneiderter Inhibitoren J Breidenbach, C Lemke, T Pillaiyar, L Schäkel, G Al Hamwi, M Diett, ... Angewandte Chemie 133 (18), 10515-10521, 2021 | 1 | 2021 |
Marco Idzko, Medical University of Vienna, Austria NJ Geraghty, OM Vanakker, CE Müller, G Bendas, V Lopez, HJM Schuh, ... | | 2023 |