CRISPR-based gene editing enables FOXP3 gene repair in IPEX patient cells M Goodwin, E Lee, U Lakshmanan, S Shipp, L Froessl, F Barzaghi, ... Science advances 6 (19), eaaz0571, 2020 | 99 | 2020 |
In vitro generation of red blood cells for transfusion medicine: Progress, prospects and challenges E Lee, J Sivalingam, ZR Lim, G Chia, LG Shi, M Roberts, YH Loh, ... Biotechnology advances 36 (8), 2118-2128, 2018 | 33 | 2018 |
Decellularized material as scaffolds for tissue engineering studies in long gap esophageal atresia E Lee, A Milan, L Urbani, P De Coppi, MW Lowdell Expert opinion on biological therapy 17 (5), 573-584, 2017 | 33 | 2017 |
Co-Expression of FOXP3FL and FOXP3Δ2 isoforms is required for optimal treg-like cell phenotypes and suppressive function Y Sato, J Liu, E Lee, R Perriman, MG Roncarolo, R Bacchetta Frontiers in Immunology 12, 752394, 2021 | 21 | 2021 |
Defined Serum‐Free Medium for Bioreactor Culture of an Immortalized Human Erythroblast Cell Line E Lee, ZR Lim, HY Chen, BX Yang, ATL Lam, AKL Chen, J Sivalingam, ... Biotechnology Journal 13 (4), 1700567, 2018 | 20 | 2018 |
Towards gene therapy for IPEX syndrome S Borna, E Lee, Y Sato, R Bacchetta European Journal of Immunology 52 (5), 705-716, 2022 | 18 | 2022 |
BHLHE40 Regulates IL-10 and IFN-γ Production in T Cells but Does Not Interfere With Human Type 1 Regulatory T Cell Differentiation MJ Uyeda, RA Freeborn, B Cieniewicz, R Romano, P Chen, JMH Liu, ... Frontiers in immunology 12, 683680, 2021 | 14 | 2021 |
Design of experiments as a decision tool for cell therapy manufacturing E Lee, D Shah, M Porteus, JF Wright, R Bacchetta Cytotherapy 24 (6), 590-596, 2022 | 6 | 2022 |
Loss of FOXP3 function causes expansion of two pools of autoreactive T cells in patients with IPEX syndrome Š Borna, E Lee, U Lakshmanan, M Mavers, M Narula, A Ramachandran, ... bioRxiv, 2022.07. 10.499494, 2022 | 3 | 2022 |
Gene editing using CRISPR enables FOXP3 gene repair in HSPCs and IPEX patient T cells E Lee, M Goodwin, U Lakshmanan, S Shipp, M Pavel-Dinu, M Porteus, ... Cytotherapy 22 (5), S20, 2020 | 3 | 2020 |
Identification of unstable regulatory and autoreactive effector T cells that are expanded in patients with FOXP3 mutations Š Borna, E Lee, J Nideffer, A Ramachandran, B Wang, J Baker, M Mavers, ... Science Translational Medicine 15 (727), eadg6822, 2023 | 2 | 2023 |
CRISPR-based gene editing enables gene repair in IPEX patient cells. M Goodwin, E Lee, U Lakshmanan, S Shipp, L Froessl, F Barzaghi, ... | 1 | 2020 |
Novel Humanized Loss-of-Function NF1 Mouse Model of Juvenile Myelomonocytic Leukemia R Sinha, R Patil, R Romano, E Lee, Z Yao, YL Liu, MH Porteus, ... Blood 140 (Supplement 1), 9765-9766, 2022 | | 2022 |
Two is Better Than One: CRISPR/Cas9 Based Gene Editing with FOXP3 Isoforms for IPEX Therapy E Lee, S Borna, Y Sato, R Bacchetta, MG Roncarolo, M Porteus MOLECULAR THERAPY 30 (4), 34-34, 2022 | | 2022 |
Loss of Treg identity in IPEX patients is associated with increase autoreactivity in Teff cells S Borna, E Lee, U Lakshmanan, M Narula, J Schulze, A Ramachandran, ... JOURNAL OF CLINICAL IMMUNOLOGY 42 (SUPPL 1), S78-S79, 2022 | | 2022 |
Genome Editing with Crispr/Cas9 to Study and Treat Primary Immune Regulatory Disorders EYZ Lee Stanford University, 2022 | | 2022 |
CRISPR-Based Therapy for IPEX Syndrome as a Model of Genetic Autoimmunity M Goodwin, E Lee, U Lakshmanan, S Shipp, MG Roncarolo, M Porteus, ... MOLECULAR THERAPY 26 (5), 95-96, 2018 | | 2018 |
SUPERIOR RED BLOOD CELL GENERATION FROM HUMAN PLURIPOTENT STEM CELLS VIA A NOVEL MICROCARRFER BASED EMBRYOID BODY PLATFORM J Sivalingam, E Lee, A Lam, A Chen, S Reuveny, S Oh CYTOTHERAPY 18 (6), S32-S33, 2016 | | 2016 |
Superior Red Blood Cell Generation From Human Pluripotent Stem Cells via a Novel Microcarrier Based Embryoid Body Platform J Sivalingam, E Lee, A Lam, A Chen, S Reuveny, S Oh Cytotherapy 18 (6), S41-S42, 2016 | | 2016 |