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Ashwanth Christopher Francis
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Single HIV-1 imaging reveals progression of infection through CA-dependent steps of docking at the nuclear pore, uncoating, and nuclear transport
AC Francis, GB Melikyan
Cell host & microbe 23 (4), 536-548. e6, 2018
1852018
Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells
AC Francis, M Marin, J Shi, C Aiken, GB Melikyan
PLoS pathogens 12 (6), e1005709, 2016
1362016
Structural and mechanistic bases for a potent HIV-1 capsid inhibitor
SM Bester, G Wei, H Zhao, D Adu-Ampratwum, N Iqbal, VV Courouble, ...
Science 370 (6514), 360-364, 2020
1342020
HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains
AC Francis, M Marin, PK Singh, V Achuthan, MJ Prellberg, ...
Nature communications 11 (1), 3505, 2020
1242020
Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1
JE Hammonds, N Beeman, L Ding, S Takushi, AC Francis, JJ Wang, ...
PLoS pathogens 13 (1), e1006181, 2017
912017
Proteome-wide characterization of the RNA-binding protein RALY-interactome using the in vivo-biotinylation-pulldown-quant (iBioPQ) approach
S Tenzer, A Moro, J Kuharev, AC Francis, L Vidalino, A Provenzani, ...
Journal of proteome research 12 (6), 2869-2884, 2013
602013
HIV-1 uncoating and nuclear import precede the completion of reverse transcription in cell lines and in primary macrophages
AC Francis, M Marin, MJ Prellberg, K Palermino-Rowland, GB Melikyan
Viruses 12 (11), 1234, 2020
542020
Sec24C is an HIV-1 host dependency factor crucial for virus replication
SV Rebensburg, G Wei, RC Larue, J Lindenberger, AC Francis, ...
Nature microbiology 6 (4), 435-444, 2021
482021
Exploring modifications of an HIV-1 capsid inhibitor: design, synthesis, and mechanism of action
JP Xu, AC Francis, ME Meuser, M Mankowski, RG Ptak, AA Rashad, ...
Journal of drug design and research 5 (2), 2018
482018
HIV-1 integrase tetramers are the antiviral target of pyridine-based allosteric integrase inhibitors
PC Koneru, AC Francis, N Deng, SV Rebensburg, AC Hoyte, ...
Elife 8, e46344, 2019
442019
Live-cell imaging of early steps of single HIV-1 infection
AC Francis, GB Melikyan
Viruses 10 (5), 275, 2018
402018
A novel phenotype links HIV-1 capsid stability to cGAS-mediated DNA sensing
MA Siddiqui, A Saito, UD Halambage, D Ferhadian, DK Fischer, ...
Journal of virology 93 (16), 10.1128/jvi. 00706-19, 2019
352019
Second generation imaging of nuclear/cytoplasmic HIV-1 complexes
AC Francis, C Di Primio, V Quercioli, P Valentini, A Boll, G Girelli, ...
AIDS research and human retroviruses 30 (7), 717-726, 2014
322014
An improved labeling strategy enables automated detection of single-virus fusion and assessment of HIV-1 protease activity in single virions
C Sood, AC Francis, TM Desai, GB Melikyan
Journal of Biological Chemistry 292 (49), 20196-20207, 2017
242017
Role of phosphorylation in the nuclear biology of HIV-1
A C Francis, C Di Primio, A Allouch, A Cereseto
Current medicinal chemistry 18 (19), 2904-2912, 2011
222011
Prion-like low complexity regions enable avid virus-host interactions during HIV-1 infection
G Wei, N Iqbal, VV Courouble, AC Francis, PK Singh, A Hudait, ...
Nature Communications 13 (1), 5879, 2022
192022
Prevalence and pattern of cross-reacting antibodies to HIV in patients with tuberculosis
S Swaminathan, LE Hanna, JC Sundaramurthi, A Leonard, ...
AIDS research and human retroviruses 24 (7), 941-946, 2008
182008
Localization and functions of native and eGFP-tagged capsid proteins in HIV-1 particles
AC Francis, A Cereseto, PK Singh, J Shi, E Poeschla, AN Engelman, ...
PLoS Pathogens 18 (8), e1010754, 2022
102022
HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains. Nat Commun 11: 3505
AC Francis, M Marin, PK Singh, V Achuthan, MJ Prellberg, ...
102020
Sec24C is an HIV-1 host dependency factor crucial for virus replication. Nat Microbiol 6: 435–444
SV Rebensburg, G Wei, RC Larue, J Lindenberger, AC Francis, ...
82021
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