| Signal characteristics of G protein‐transactivated EGF receptor H Daub, C Wallasch, A Lankenau, A Herrlich, A Ullrich The EMBO journal, 1997 | 832 | 1997 |
| Gonadotropin-releasing Hormone Receptor Initiates Multiple Signaling Pathways by Exclusively Coupling to Gq/11Proteins R Grosse, A Schmid, T Schoneberg, A Herrlich, P Muhn, G Schultz, ... Journal of Biological Chemistry 275 (13), 9193-9200, 2000 | 192 | 2000 |
| Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic, acid-stimulated mitogenic activity in L cells A Herrlich, H Daub, A Knebel, P Herrlich, A Ullrich, G Schultz, ... Proceedings of the National Academy of Sciences 95 (15), 8985-8990, 1998 | 191 | 1998 |
| Involvement of Gs and Gi proteins in dual coupling of the luteinizing hormone receptor to adenylyl cyclase and phospholipase C A Herrlich, B Kühn, R Grosse, A Schmid, G Schultz, T Gudermann Journal of Biological Chemistry 271 (28), 16764-16772, 1996 | 188 | 1996 |
| FOXM1 drives proximal tubule proliferation during repair from acute ischemic kidney injury M Chang-Panesso, FF Kadyrov, M Lalli, H Wu, S Ikeda, E Kefaloyianni, ... The Journal of clinical investigation 129 (12), 5501-5517, 2019 | 137 | 2019 |
| ADAM17 substrate release in proximal tubule drives kidney fibrosis E Kefaloyianni, ML Muthu, J Kaeppler, X Sun, V Sabbisetti, A Chalaris, ... JCI insight 1 (13), 2016 | 134 | 2016 |
| Proteolytic Activity Matrix Analysis (PrAMA) for simultaneous determination of multiple protease activities MA Miller, L Barkal, K Jeng, A Herrlich, M Moss, LG Griffith, ... Integrative Biology 3 (4), 422-438, 2011 | 116 | 2011 |
| Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways M Dang, N Armbruster, MA Miller, E Cermeno, M Hartmann, GW Bell, ... Proceedings of the National Academy of Sciences 110 (24), 9776-9781, 2013 | 98 | 2013 |
| Epidermal growth factor receptor tyrosine kinase mediates Ras activation by gonadotropin-releasing hormone R Grosse, S Roelle, A Herrlich, J Höhn, T Gudermann Journal of Biological Chemistry 275 (16), 12251-12260, 2000 | 86 | 2000 |
| Who decides when to cleave an ectodomain? M Hartmann, A Herrlich, P Herrlich Trends in biochemical sciences 38 (3), 111-120, 2013 | 82 | 2013 |
| PI3kα and STAT1 interplay regulates human mesenchymal stem cell immune polarization M Mounayar, E Kefaloyianni, B Smith, Z Solhjou, OH Maarouf, J Azzi, ... Stem cells 33 (6), 1892-1901, 2015 | 79 | 2015 |
| Identification of kidney injury–released circulating osteopontin as causal agent of respiratory failure FZ Khamissi, L Ning, E Kefaloyianni, H Dun, A Arthanarisami, A Keller, ... Science advances 8 (8), eabm5900, 2022 | 60 | 2022 |
| Inside-out Regulation of Ectodomain Cleavage of Cluster-of-Differentiation-44 (CD44) and of Neuregulin-1 Requires Substrate Dimerization*♦ M Hartmann, LM Parra, A Ruschel, C Lindner, H Morrison, A Herrlich, ... Journal of Biological Chemistry 290 (28), 17041-17054, 2015 | 59 | 2015 |
| Epidermal growth factor (EGF) ligand release by substrate-specific a disintegrin and metalloproteases (ADAMs) involves different protein kinase C (PKC) isoenzymes depending on … M Dang, K Dubbin, A D'Aiello, M Hartmann, H Lodish, A Herrlich Journal of Biological Chemistry 286 (20), 17704-17713, 2011 | 57 | 2011 |
| Proximal Tubule–Derived Amphiregulin Amplifies and Integrates Profibrotic EGF Receptor Signals in Kidney Fibrosis E Kefaloyianni, MRK Raja, J Schumacher, ML Muthu, V Krishnadoss, ... Journal of the American Society of Nephrology 30 (12), 2370-2383, 2019 | 51 | 2019 |
| Distinct intracellular domain substrate modifications selectively regulate ectodomain cleavage of NRG1 or CD44 LM Parra, M Hartmann, S Schubach, Y Li, P Herrlich, A Herrlich Molecular and cellular biology 35 (19), 3381-3395, 2015 | 42 | 2015 |
| Tumor suppressor NF2 blocks cellular migration by inhibiting ectodomain cleavage of CD44 M Hartmann, LM Parra, A Ruschel, S Böhme, Y Li, H Morrison, A Herrlich, ... Molecular Cancer Research 13 (5), 879-890, 2015 | 42 | 2015 |
| Ectodomain cleavage of the EGF ligands HB-EGF, neuregulin1-β, and TGF-α is specifically triggered by different stimuli and involves different PKC isoenzymes A Herrlich, E Klinman, J Fu, C Sadegh, H Lodish The FASEB Journal 22 (12), 4281, 2008 | 42 | 2008 |
| Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC K Zhang, L Jones, S Lim, CA Maher, D Adkins, J Lewis, RJ Kimple, ... Oncotarget 5 (19), 9281, 2014 | 37 | 2014 |
| Role of proneuregulin 1 cleavage and human epidermal growth factor receptor activation in hypertonic aquaporin induction A Herrlich, V Leitch, LS King Proceedings of the National Academy of Sciences 101 (44), 15799-15804, 2004 | 25 | 2004 |
Eirini KefalogianniWashington University in St. Louis, School of MedicineVerified email at wustl.edu
