| Topoisomerase II can unlink replicating DNA by precatenane removal I Lucas, T Germe, M Chevrier-Miller, O Hyrien The EMBO Journal 20 (22), 6509-6519, 2001 | 131 | 2001 |
| DNA topoisomerase inhibitors: trapping a DNA-cleaving machine in motion BD Bax, G Murshudov, A Maxwell, T Germe Journal of molecular biology 431 (18), 3427-3449, 2019 | 108 | 2019 |
| Thiophene antibacterials that allosterically stabilize DNA-cleavage complexes with DNA gyrase PF Chan, T Germe, BD Bax, J Huang, RK Thalji, E Bacqué, A Checchia, ... Proceedings of the National Academy of Sciences 114 (22), E4492-E4500, 2017 | 71 | 2017 |
| DNA replication timing is deterministic at the level of chromosomal domains but stochastic at the level of replicons in Xenopus egg extracts H Labit, I Perewoska, T Germe, O Hyrien, K Marheineke Nucleic acids research 36 (17), 5623-5634, 2008 | 56 | 2008 |
| Topoisomerase II–DNA complexes trapped by ICRF‐193 perturb chromatin structure T Germe, O Hyrien EMBO reports 6 (8), 729-735, 2005 | 44 | 2005 |
| A non‐canonical function of topoisomerase II in disentangling dysfunctional telomeres T Germe, K Miller, JP Cooper The EMBO Journal 28 (18), 2803-2811, 2009 | 39 | 2009 |
| Potent DNA gyrase inhibitors bind asymmetrically to their target using symmetrical bifurcated halogen bonds A Kolarič, T Germe, M Hrast, CEM Stevenson, DM Lawson, NP Burton, ... Nature communications 12 (1), 150, 2021 | 31 | 2021 |
| A new class of antibacterials, the imidazopyrazinones, reveal structural transitions involved in DNA gyrase poisoning and mechanisms of resistance T Germe, J Vörös, F Jeannot, T Taillier, RA Stavenger, E Bacqué, ... Nucleic acids research 46 (8), 4114-4128, 2018 | 29 | 2018 |
| DNA topoisomerase IIα controls replication origin cluster licensing and firing time in Xenopus egg extracts V Gaggioli, B Le Viet, T Germe, O Hyrien Nucleic acids research 41 (15), 7313-7331, 2013 | 26 | 2013 |
| Imidazopyrazinones (IPYs): Non-quinolone bacterial topoisomerase inhibitors showing partial cross-resistance with quinolones F Jeannot, T Taillier, P Despeyroux, S Renard, A Rey, M Mourez, ... Journal of Medicinal Chemistry 61 (8), 3565-3581, 2018 | 13 | 2018 |
| De novo design of type II topoisomerase inhibitors as potential antimicrobial agents targeting a novel binding region KM Orritt, L Feng, JF Newell, JN Sutton, S Grossman, T Germe, LR Abbott, ... RSC Medicinal Chemistry 13 (7), 831-839, 2022 | 3 | 2022 |
| Non-quinolone topoisomerase inhibitors A Maxwell, NG Bush, T Germe, SJ McKie Antimicrobial Resistance in the 21st Century, 593-618, 2018 | 3 | 2018 |
| Rapid, DNA-induced subunit exchange by DNA gyrase T Germe, NG Bush, V Baskerville, D Saman, J Benesch, A Maxwell eLife 12, 2023 | 1 | 2023 |
| Rapid, DNA-induced interface swapping by DNA gyrase T Germe, NG Bush, V Baskerville, D Saman, J Benesch, A Maxwell bioRxiv, 2022.09. 08.507137, 2022 | | 2022 |
| Xenopus egg extracts as a model system for understanding the role of topoisomerase II in the chromosome cycle O HYRIEN, T GERME Recent developments in nucleic acids research, 75-101, 2004 | | 2004 |
| Supplementary Material to: DNA topoisomerase IIα controls replication origin cluster licensing and firing time in Xenopus egg extracts V Gaggioli, B Le Viet, T Germe, O Hyrien | | |
