Daniel J. Murphy

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Nathiya MuthalaguAsst.Professor, Dept. of Biotechnology, IIT MadrasVerified email at iitm.ac.in
Gerard EvanFrancis Crick InstituteVerified email at crick.ac.uk
Karen BlythCRUK Beatson InstituteVerified email at beatson.gla.ac.uk
Melissa R JunttilaORIC PharmaceuticalsVerified email at oricpharma.com
Anthony KarnezisUniversity of California DavisVerified email at ucdavis.edu
Seth B. Coffelt, Ph.D.University of Glasgow/CRUK Beatson InstituteVerified email at glasgow.ac.uk
Stephen TaitCancer Research UK Beatson Institute and University of GlasgowVerified email at glasgow.ac.uk
lsoucekPrincipal Investigator, Vall d'Hebron Institute of OncologyVerified email at vhio.net
Jonathan WhitfieldSenior Investigator, VHIOVerified email at vhio.net
Nicole M. SodirGenentech, incVerified email at gene.com
Leo M. CarlinCancer Research UK Scotland InstituteVerified email at glasgow.ac.uk
Martin EilersProfessor of BiochemistryVerified email at biozentrum.uni-wuerzburg.de
Kevin BlythProfessor of Respiratory MedicineVerified email at glasgow.ac.uk
Sara ZanivanCRUK Scotland InstituteVerified email at beatson.gla.ac.uk
Anthony ChalmersChair of Clinical Oncology, University of GlasgowVerified email at glasgow.ac.uk
stefan kempaBIMSB@MDC Berlin-BuchVerified email at mdc-berlin.de
Torsten WüstefeldAssociate Professor of Molecular Metabolism, LKC, NTUVerified email at ntu.edu.sg
Lars ZenderProfessor of Medical Oncology, Director & Chair, Dept. of Medical Oncology & Pneumology, University Hospital Tübingen, 72076 Tübingen, GermanyVerified email at med.uni-tuebingen.de
Kristopher A. SarosiekHarvard School of Public Health (Dana-Farber Cancer Institute; Harvard Medical School)Verified email at hsph.harvard.edu
Anthony LetaiProfessor of Medicine, Dana-Farber Cancer InstituteVerified email at dfci.harvard.edu

Daniel J. Murphy

University of Glasgow, School of Cancer Sciences

Verified email at glasgow.ac.uk - Homepage

Lung Cancer Mesothelioma MYC NUAK1 Oxidative Stress


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Modelling Myc inhibition as a cancer therapy L Soucek, J Whitfield, CP Martins, AJ Finch, DJ Murphy, NM Sodir, ... Nature 455 (7213), 679-683, 2008	975	2008
Distinct thresholds govern Myc's biological output in vivo DJ Murphy, MR Junttila, L Pouyet, A Karnezis, K Shchors, DA Bui, ... Cancer cell 14 (6), 447-457, 2008	519	2008
Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death G Ichim, J Lopez, SU Ahmed, N Muthalagu, E Giampazolias, ME Delgado, ... Molecular cell 57 (5), 860-872, 2015	444	2015
Deregulated MYC expression induces dependence upon AMPK-related kinase 5 L Liu, J Ulbrich, J Müller, T Wüstefeld, L Aeberhard, TR Kress, ... Nature 483 (7391), 608-612, 2012	313	2012
MYC-dependent regulation and prognostic role of CIP2A in gastric cancer A Khanna, C Böckelman, A Hemmes, MR Junttila, JP Wiksten, M Lundin, ... JNCI: Journal of the National Cancer Institute 101 (11), 793-805, 2009	271	2009
Developmental Regulation of Mitochondrial Apoptosis by c-Myc Governs Age-and Tissue-Specific Sensitivity to Cancer Therapeutics KA Sarosiek, C Fraser, N Muthalagu, PD Bhola, W Chang, SK McBrayer, ... Cancer Cell, 2016	254	2016
Oncogenic Myc Induces Expression of Glutamine Synthetase through Promoter Demethylation AJ Bott, IC Peng, Y Fan, B Faubert, L Zhao, J Li, S Neidler, Y Sun, N Jaber, ... Cell metabolism 22 (6), 1068-1077, 2015	252	2015
Interleukin-6-and cyclic AMP-mediated signaling potentiates neuroendocrine differentiation of LNCaP prostate tumor cells PD Deeble, DJ Murphy, SJ Parsons, ME Cox Molecular and cellular biology 21 (24), 8471-8482, 2001	242	2001
Human SWI-SNF component BRG1 represses transcription of the c-fos gene DJ Murphy, S Hardy, DA Engel Molecular and cellular biology 19 (4), 2724-2733, 1999	183	1999
Apoptotic cell death in disease—Current understanding of the NCCD 2023 I Vitale, F Pietrocola, E Guilbaud, SA Aaronson, JM Abrams, D Adam, ... Cell Death & Differentiation 30 (5), 1097-1154, 2023	172	2023
Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism AJ Bott, J Shen, C Tonelli, L Zhan, N Sivaram, YP Jiang, X Yu, V Bhatt, ... Cell reports 29 (5), 1287-1298. e6, 2019	148	2019
Repression of the type I interferon pathway underlies MYC & KRAS-dependent evasion of NK & B cells in pancreatic ductal adenocarcinoma N Muthalagu, T Monteverde, X Raffo-Iraolagoitia, R Wiesheu, D Whyte, ... Cancer Discovery, 2020	140	2020
The ERBB network facilitates KRAS-driven lung tumorigenesis B Kruspig, T Monteverde, S Neidler, A Hock, E Kerr, C Nixon, W Clark, ... Science Translational Medicine 10 (446), eaao2565, 2018	108	2018
MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance AS Farrell, AD Rhim, BC Sheppard, BL Allen-Petersen, C Pelz, ... Nature Communications 8, 1728, 2017	105	2017
Evidence of cancer‐promoting roles for AMPK and related kinases T Monteverde, N Muthalagu, J Port, DJ Murphy The FEBS journal 282 (24), 4658-4671, 2015	98	2015
CRISPR/Cas9-derived models of ovarian high grade serous carcinoma targeting Brca1, Pten and Nf1, and correlation with platinum sensitivity JB Walton, M Farquharson, S Mason, J Port, B Kruspig, S Dowson, ... Scientific Reports 7, 16827, 2017	96	2017
A Neuronal Relay Mediates a Nutrient Responsive Gut/Fat Body Axis Regulating Energy Homeostasis in Adult Drosophila JBC Alessandro Scopelliti, Christin Bauer, Yachuan Yu, Tong Zhang, Bjo ̈rn ... Cell Metabolism 29, 2019	94	2019
BIM is the primary mediator of MYC-induced apoptosis in multiple solid tissues N Muthalagu, MR Junttila, KE Wiese, E Wolf, J Morton, B Bauer, GI Evan, ... Cell reports 8 (5), 1347-1353, 2014	87	2014
Defining the temporal requirements for Myc in the progression and maintenance of skin neoplasia I Flores, DJ Murphy, LB Swigart, U Knies, GI Evan Oncogene 23 (35), 5923-5930, 2004	81	2004
In vitro evidence for senescent multinucleated melanocytes as a source for tumor-initiating cells C Leikam, AL Hufnagel, C Otto, DJ Murphy, B Mühling, S Kneitz, I Nanda, ... Cell death & disease 6 (4), e1711, 2015	78	2015

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