Panorama of ancient metazoan macromolecular complexes C Wan, B Borgeson, S Phanse, F Tu, K Drew, G Clark, X Xiong, O Kagan, ... Nature 525 (7569), 339-344, 2015 | 527 | 2015 |
Actionable cytopathogenic host responses of human alveolar type 2 cells to SARS-CoV-2 RM Hekman, AJ Hume, RK Goel, KM Abo, J Huang, BC Blum, RB Werder, ... Molecular cell 80 (6), 1104-1122. e9, 2020 | 115 | 2020 |
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities FJ Vizeacoumar, R Arnold, FS Vizeacoumar, M Chandrashekhar, ... Molecular systems biology 9 (1), 696, 2013 | 108 | 2013 |
Organoids model transcriptional hallmarks of oncogenic KRAS activation in lung epithelial progenitor cells AFM Dost, AL Moye, M Vedaie, LM Tran, E Fung, D Heinze, ... Cell Stem Cell 27 (4), 663-678. e8, 2020 | 104 | 2020 |
Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy L Jiang, W Lin, C Zhang, PEA Ash, M Verma, J Kwan, E van Vliet, Z Yang, ... Molecular cell 81 (20), 4209-4227. e12, 2021 | 101 | 2021 |
SARS-CoV-2 spike protein interacts with multiple innate immune receptors C Gao, J Zeng, N Jia, K Stavenhagen, Y Matsumoto, H Zhang, J Li, ... BioRxiv, 2020 | 99 | 2020 |
DLG5 connects cell polarity and Hippo signaling protein networks by linking PAR-1 with MST1/2 J Kwan, A Sczaniecka, EH Arash, L Nguyen, CC Chen, S Ratkovic, ... Genes & development 30 (24), 2696-2709, 2016 | 81 | 2016 |
Native KCC2 interactome reveals PACSIN1 as a critical regulator of synaptic inhibition V Mahadevan, CS Khademullah, Z Dargaei, J Chevrier, P Uvarov, J Kwan, ... Elife 6, e28270, 2017 | 56 | 2017 |
Modulation of lymphocyte-mediated tissue repair by rational design of heterocyclic aryl hydrocarbon receptor agonists J Chen, CA Haller, FE Jernigan, SK Koerner, DJ Wong, Y Wang, ... Science advances 6 (3), eaay8230, 2020 | 41 | 2020 |
Loss of G-protein pathway suppressor 2 promotes tumor growth through activation of AKT signaling S Chan, E Smith, Y Gao, J Kwan, BC Blum, AM Tilston-Lunel, I Turcinovic, ... Frontiers in Cell and Developmental Biology 8, 608044, 2021 | 17 | 2021 |
DNAJB1-PRKACA in HEK293T cells induces LINC00473 overexpression that depends on PKA signaling SS Kim, I Kycia, M Karski, RK Ma, EA Bordt, J Kwan, A Karki, E Winter, ... Plos one 17 (2), e0263829, 2022 | 8 | 2022 |
Neuralized-like protein 4 (NEURL4) mediates ADP-ribosylation of mitochondrial proteins MD Cardamone, Y Gao, J Kwan, V Hayashi, M Sheeran, J Xu, J English, ... Journal of Cell Biology 221 (3), e202101021, 2022 | 8 | 2022 |
Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes S Phanse, C Wan, B Borgeson, F Tu, K Drew, G Clark, X Xiong, O Kagan, ... Data in brief 6, 715-721, 2016 | 7 | 2016 |
Multiomic metabolic enrichment network analysis reveals metabolite–protein physical interaction subnetworks altered in cancer BC Blum, W Lin, ML Lawton, Q Liu, J Kwan, I Turcinovic, R Hekman, P Hu, ... Molecular & Cellular Proteomics 21 (1), 2022 | 5 | 2022 |
ADP-ribosylation of mitochondrial proteins is mediated by Neuralized-like protein 4 (NEURL4) MD Cardamone, Y Gao, J Kwan, V Hayashi, M Sheeran, J Xu, J English, ... bioRxiv, 2020.12. 28.424513, 2020 | 5 | 2020 |
Simple and effective affinity purification procedures for mass spectrometry-based identification of protein-protein interactions in cell signaling pathways JHM Kwan, A Emili Proteomics in Systems Biology: Methods and Protocols, 181-187, 2016 | 3 | 2016 |
SND1 binds to ERG and promotes tumor growth in genetic mouse models of prostate cancer SY Liao, D Rudoy, SB Frank, LT Phan, O Klezovitch, J Kwan, I Coleman, ... Nature communications 14 (1), 7435, 2023 | 2 | 2023 |
Human pluripotent stem cell modeling of alveolar type 2 cell dysfunction caused by ABCA3 mutations YL Sun, EE Hennessey, H Heins, P Yang, C Villacorta-Martin, J Kwan, ... The Journal of clinical investigation 134 (2), 2024 | 1 | 2024 |
Factor quinolinone inhibitors disrupt spindles and multiple LSF (TFCP2)-protein interactions in mitosis, including with microtubule-associated proteins SA Yunes, JLS Willoughby, JH Kwan, JM Biagi, N Pokharel, HG Chin, ... Plos one 17 (6), e0268857, 2022 | 1 | 2022 |
Multi-modal comparison of molecular programs driving nurse cell death and clearance in Drosophila melanogaster oogenesis S Bandyadka, DPV Lebo, A Mondragon, SB Serizier, J Kwan, JS Peterson, ... bioRxiv, 2024.03. 12.584558, 2024 | | 2024 |