Hepatic leukemia factor maintains quiescence of hematopoietic stem cells and protects the stem cell pool during regeneration K Komorowska, A Doyle, M Wahlestedt, A Subramaniam, S Debnath, ... Cell reports 21 (12), 3514-3523, 2017 | 92 | 2017 |
Efficient and nontoxic biomolecule delivery to primary human hematopoietic stem cells using nanostraws L Schmiderer, A Subramaniam, K Žemaitis, A Bäckström, D Yudovich, ... Proceedings of the National Academy of Sciences 117 (35), 21267-21273, 2020 | 52 | 2020 |
Lysine-specific demethylase 1A restricts ex vivo propagation of human HSCs and is a target of UM171 A Subramaniam, K Žemaitis, MS Talkhoncheh, D Yudovich, A Bäckström, ... Blood, The Journal of the American Society of Hematology 136 (19), 2151-2161, 2020 | 45 | 2020 |
BCR-ABL mediated repression of miR-223 results in the activation of MEF2C and PTBP2 in chronic myeloid leukemia S Agatheeswaran, S Singh, S Biswas, G Biswas, N Chandra Pattnayak, ... Leukemia 27 (7), 1578-1580, 2013 | 34 | 2013 |
Endothelial protein C receptor (EPCR) expression marks human fetal liver hematopoietic stem cells A Subramaniam, MS Talkhoncheh, M Magnusson, J Larsson Haematologica 104 (2), e47, 2019 | 32 | 2019 |
Identification and functional characterization of the miRNA-gene regulatory network in chronic myeloid leukemia lineage negative cells S Agatheeswaran, NC Pattnayak, S Chakraborty Scientific Reports 6 (1), 32493, 2016 | 27 | 2016 |
Combined lentiviral-and RNA-mediated CRISPR/Cas9 delivery for efficient and traceable gene editing in human hematopoietic stem and progenitor cells D Yudovich, A Bäckström, L Schmiderer, K Žemaitis, A Subramaniam, ... Scientific Reports 10 (1), 22393, 2020 | 24 | 2020 |
HMGA2 promotes long-term engraftment and myeloerythroid differentiation of human hematopoietic stem and progenitor cells P Kumar, D Beck, R Galeev, JAI Thoms, MS Talkhoncheh, I de Jong, ... Blood Advances 3 (4), 681-691, 2019 | 24 | 2019 |
PTBP2 exon 10 inclusion is associated with the progression of CML and it is BCR-ABL1 dependent SR Nandagopalan, S Agatheeswaran, Y Vadlamudi, S Biswas, G Biswas, ... The International Journal of Biochemistry & Cell Biology 109, 69-75, 2019 | 6 | 2019 |
Transient inhibition of NF-κB signaling enhances ex vivo propagation of human hematopoietic stem cells MS Talkhoncheh, A Subramaniam, M Magnusson, P Kumar, J Larsson, ... haematologica 103 (9), 1444, 2018 | 6 | 2018 |
Ecotropic viral integration site I regulates alpha1, 6-fucosyl transferase expression and blocks erythropoiesis in chronic myeloid leukemia N Kuila, KB Nayak, A Halder, S Agatheeswaran, G Biswas, S Biswas, ... Leukemia & Lymphoma 58 (8), 1941-1947, 2017 | 6 | 2017 |
The stem cell–supporting small molecule UM171 triggers Cul3-KBTBD4–mediated degradation of ELM2 domain–harboring proteins K Žemaitis, S Ghosh, J Hansson, A Subramaniam Journal of Biological Chemistry 299 (5), 2023 | 2 | 2023 |
RNAi Screen Identifies MTA1 as an Epigenetic Modifier of Differentiation Commitment in Human HSPCs K Žemaitis, A Subramaniam, R Galeev, A Prosz, M Jassinskaja, ... Experimental Hematology 115, 20-29, 2022 | 2 | 2022 |
Combinatorial gene targeting in primary human hematopoietic stem and progenitor cells A Bäckström, D Yudovich, K Žemaitis, L Nilsén Falck, A Subramaniam, ... Scientific Reports 12 (1), 18169, 2022 | 2 | 2022 |
Inducing synthetic lethality for selective targeting of acute myeloid leukemia cells harboring STAG2 mutations A Subramaniam, C Sandén, L Moura-Castro, K Žemaitis, L Schmiderer, ... Haematologica 107 (9), 2271, 2022 | 2 | 2022 |
3038–UM171 PROMOTES EX VIVO EXPANSION OF HUMAN HSCS BY TARGETING THE EPIGENETIC MODULATOR COREST FOR DEGRADATION A Subramaniam, K Zemaitis, MS Talkhoncheh, A Bäckström, M Gaetani, ... Experimental Hematology 88, S50, 2020 | 2 | 2020 |
Small molecule screens identify CDK8-inhibitors as candidate Diamond-Blackfan anemia drugs J Chen, K Siva, T Rzymski, L Johansson, T Lundbäck, LN Villacis, F Ek, ... Blood 132, 753, 2018 | 2 | 2018 |
Ciclopirox ethanolamine preserves the immature state of human HSCs by mediating intracellular iron content MS Talkhoncheh, A Baudet, F Ek, A Subramaniam, YR Kao, N Miharada, ... Blood Advances 7 (24), 7407-7417, 2023 | 1 | 2023 |
Functional and molecular profiling of hematopoietic stem cells during regeneration A Rydström, THM Grahn, A Niroula, E Mansell, M van der Garde, ... Experimental Hematology 127, 40-51, 2023 | 1 | 2023 |
3020–RNA-INTERFERENCE SCREEN IDENTIFIES MTA1 AS A REGULATOR OF HUMAN HEMATOPOIETIC STEM AND PROGENITOR CELLS K Zemaitis, A Prosz, A Subramaniam, R Galeev, M Jassinskaja, ... Experimental Hematology 111, S54-S55, 2022 | 1 | 2022 |