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Shelby Barnett
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Gaining mechanistic insight into coproporphyrin I as endogenous biomarker for OATP1B‐mediated drug–drug interactions using population pharmacokinetic modeling and simulation
S Barnett, K Ogungbenro, K Ménochet, H Shen, Y Lai, WG Humphreys, ...
Clinical Pharmacology & Therapeutics 104 (3), 564-574, 2018
652018
In vivo screening and discovery of novel candidate thalidomide analogs in the zebrafish embryo and chicken embryo model systems
SL Beedie, HM Rore, S Barnett, CH Chau, W Luo, NH Greig, WD Figg, ...
Oncotarget 7 (22), 33237, 2016
452016
Comprehensive evaluation of the utility of 20 endogenous molecules as biomarkers of OATP1B inhibition compared with rosuvastatin and coproporphyrin I
S Barnett, K Ogungbenro, K Menochet, H Shen, WG Humphreys, ...
Journal of Pharmacology and Experimental Therapeutics 368 (1), 125-135, 2019
432019
Anticancer properties of a novel class of tetrafluorinated thalidomide analogues
SL Beedie, CJ Peer, S Pisle, ER Gardner, C Mahony, S Barnett, ...
Molecular cancer therapeutics 14 (10), 2228-2237, 2015
292015
Vincristine dosing, drug exposure and therapeutic drug monitoring in neonate and infant cancer patients
S Barnett, F Hellmann, E Parke, G Makin, DA Tweddle, C Osborne, ...
European Journal of Cancer 164, 127-136, 2022
242022
PBPK model of coproporphyrin I: evaluation of the impact of SLCO1B1 genotype, ethnicity, and sex on its inter‐individual variability
H Takita, S Barnett, Y Zhang, K Ménochet, H Shen, K Ogungbenro, ...
CPT: Pharmacometrics & Systems Pharmacology 10 (2), 137-147, 2021
242021
Clinical pharmacology of cytotoxic drugs in neonates and infants: Providing evidence-based dosing guidance
AL Nijstad, S Barnett, A Lalmohamed, IM Bérénos, E Parke, V Carruthers, ...
European Journal of Cancer 164, 137-154, 2022
132022
Over a decade of experience with carboplatin therapeutic drug monitoring in a childhood cancer setting in the United Kingdom
S Barnett, J Kong, G Makin, GJ Veal
British Journal of Clinical Pharmacology 87 (2), 256-262, 2021
92021
Pharmacokinetics and pharmacogenetics of cyclophosphamide in a neonate and infant childhood cancer patient population
S Barnett, J Errington, J Sludden, D Jamieson, V Poinsignon, A Paci, ...
Pharmaceuticals 14 (3), 272, 2021
82021
A Population Pharmacokinetic Modelling Approach to Unravel the Complex Pharmacokinetics of Vincristine in Children
AL Nijstad, WY Chu, E de Vos-Kerkhof, CF Enters-Weijnen, ...
Pharmaceutical Research 39 (10), 2487-2495, 2022
72022
Perspectives and expertise in establishing a therapeutic drug monitoring programme for challenging childhood cancer patient populations
S Barnett, V Holden, Q Campbell-Hewson, GJ Veal
Frontiers in Oncology 11, 815040, 2022
62022
Clinical utility of vinblastine therapeutic drug monitoring for the treatment of infantile myofibroma patients: A case series
V Carruthers, S Barnett, R Rees, T Arif, O Slater, R Ramanujachar, ...
Pediatric Blood & Cancer 69 (7), e29722, 2022
22022
A CRUK first-in-human phase I trial of LY3143921, a novel CDC7 inhibitor, in patients with advanced solid tumors.
PF Gallagher, G Naylor, S Bashir, X Yan, D Burke, ER Plummer, ...
Journal of Clinical Oncology 40 (16_suppl), 3103-3103, 2022
22022
Generation of evidence-based carboplatin dosing guidelines for neonates and infants
S Barnett, G Makin, DA Tweddle, C Osborne, GJ Veal
British Journal of Cancer 129 (11), 1773-1779, 2023
12023
Physiologically‐based pharmacokinetic model to predict doxorubicin and paclitaxel exposure in infants through breast milk
D Damoiseaux, F Amant, JH Beijnen, S Barnett, GJ Veal, ADR Huitema, ...
CPT: pharmacometrics & systems pharmacology 12 (12), 1931-1944, 2023
2023
GENERATION OF EVIDENCE-BASED DOSING GUIDELINES FOR NEONATES AND INFANTS RECEIVING CARBOPLATIN AND VINCRISTINE
S Barnett, G Makin, D Tweddle, C Osborne, G Veal
PEDIATRIC BLOOD & CANCER 70, S119-S120, 2023
2023
Excessive vincristine exposure in a child being treated for acute lymphoblastic leukaemia with underlying Dubin–Johnson syndrome: a case report
S Barnett, AC Nyein, M Galler, D Jamieson, M Davies, P Connor, GJ Veal
Cancer Chemotherapy and Pharmacology 92 (4), 325-328, 2023
2023
Spontaneous fractures during 13-cis retinoic acid therapy for neuroblastoma.
C Geurten, J Errington, S Barnett, H Patel, S Noor, V Saraff, GJ Veal, ...
Pediatric Blood and Cancer 70 (9), 2023
2023
Clinical utility of vinblastine therapeutic drug monitoring for the treatment of infantile myofibroma patients
V Carruthers, S Barnett, R Rees, T Arif, O Slater, R Ramanujachar, ...
2022
Application of Coproporphyrin I Pbpk Model to Evaluate the Impact of Slco1b1 Genotype, Ethnicity, and Sex on Its Oatp1b-mediated Interactions.
H Takita, S Barnett, Y Zhang, K Menochet, H Shen, K Ogungbenro, ...
Clinical Pharmacology & Therapeutics 109, S83-S83, 2021
2021
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