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Florian Tran
Florian Tran
Verified email at ikmb.uni-kiel.de
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Mapping the human genetic architecture of COVID-19
Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ...
Nature 600 (7889), 472-477, 2021
7402021
Swarm learning for decentralized and confidential clinical machine learning
S Warnat-Herresthal, H Schultze, KL Shastry, S Manamohan, ...
Nature 594 (7862), 265-270, 2021
5932021
Increased tryptophan metabolism is associated with activity of inflammatory bowel diseases
S Nikolaus, B Schulte, N Al-Massad, F Thieme, DM Schulte, J Bethge, ...
Gastroenterology 153 (6), 1504-1516. e2, 2017
4322017
Immunogenicity and safety of anti-SARS-CoV-2 mRNA vaccines in patients with chronic inflammatory conditions and immunosuppressive therapy in a monocentric cohort
UM Geisen, DK Berner, F Tran, M Sümbül, L Vullriede, M Ciripoi, HM Reid, ...
Annals of the rheumatic diseases 80 (10), 1306-1311, 2021
3752021
Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19
JP Bernardes, N Mishra, F Tran, T Bahmer, L Best, JI Blase, D Bordoni, ...
Immunity 53 (6), 1296-1314. e9, 2020
3012020
Low-avidity CD4+ T cell responses to SARS-CoV-2 in unexposed individuals and humans with severe COVID-19
P Bacher, E Rosati, D Esser, GR Martini, C Saggau, E Schiminsky, ...
Immunity 53 (6), 1258-1271. e5, 2020
2822020
Therapeutic interleukin-6 trans-signaling inhibition by olamkicept (sgp130Fc) in patients with active inflammatory bowel disease
S Schreiber, K Aden, JP Bernardes, C Conrad, F Tran, H Höper, V Volk, ...
Gastroenterology 160 (7), 2354-2366. e11, 2021
1532021
ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS–STING
K Aden, F Tran, GO Ito, R Sheibani-Tezerji, S Lipinski, JW Kuiper, ...
Journal of Experimental Medicine 215 (11), 2868-2886, 2018
1372018
Epithelial IL-23R signaling licenses protective IL-22 responses in intestinal inflammation
K Aden, A Rehman, M Falk-Paulsen, T Secher, J Kuiper, F Tran, ...
Cell reports 16 (8), 2208-2218, 2016
1012016
Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity
O Cabral-Marques, G Halpert, LF Schimke, Y Ostrinski, A Vojdani, ...
Nature communications 13 (1), 1220, 2022
962022
Activating transcription factor 6 mediates inflammatory signals in intestinal epithelial cells upon endoplasmic reticulum stress
ST Stengel, A Fazio, S Lipinski, MT Jahn, K Aden, G Ito, F Wottawa, ...
Gastroenterology 159 (4), 1357-1374. e10, 2020
882020
Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8
T Walle, JA Kraske, B Liao, B Lenoir, C Timke, E von Bohlen und Halbach, ...
Science advances 8 (12), eabh4050, 2022
722022
Detailed stratified GWAS analysis for severe COVID-19 in four European populations
F Degenhardt, D Ellinghaus, S Juzenas, J Lerga-Jaso, M Wendorff, ...
Human molecular genetics 31 (23), 3945-3966, 2022
70*2022
Epithelial RNase H2 maintains genome integrity and prevents intestinal tumorigenesis in mice
K Aden, K Bartsch, J Dahl, MAM Reijns, D Esser, R Sheibani-Tezerji, ...
Gastroenterology 156 (1), 145-159. e19, 2019
562019
Circulating levels of soluble Dipeptidylpeptidase-4 are reduced in human subjects hospitalized for severe COVID-19 infections
K Schlicht, N Rohmann, C Geisler, T Hollstein, C Knappe, K Hartmann, ...
International journal of obesity 44 (11), 2335-2338, 2020
382020
A novel unconventional T cell population enriched in Crohn’s disease
E Rosati, GR Martini, MV Pogorelyy, AA Minervina, F Degenhardt, ...
Gut 71 (11), 2194-2204, 2022
372022
Humoral protection to SARS-CoV2 declines faster in patients on TNF alpha blocking therapies
UM Geisen, M Sümbül, F Tran, DK Berner, HM Reid, L Vullriede, M Ciripoi, ...
RMD open 7 (3), e002008, 2021
342021
Leptin induces TNFα-dependent inflammation in acquired generalized lipodystrophy and combined Crohn’s disease
JF Ziegler, C Böttcher, M Letizia, C Yerinde, H Wu, I Freise, ...
Nature communications 10 (1), 5629, 2019
332019
Classic IL-6R signalling is dispensable for intestinal epithelial proliferation and repair
K Aden, A Breuer, A Rehman, H Geese, F Tran, J Sommer, GH Waetzig, ...
Oncogenesis 5 (11), e270-e270, 2016
332016
The pre-exposure SARS-CoV-2-specific T cell repertoire determines the quality of the immune response to vaccination
C Saggau, GR Martini, E Rosati, S Meise, B Messner, AK Kamps, N Bekel, ...
Immunity 55 (10), 1924-1939. e5, 2022
252022
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