Oxidation of protein kinase A regulatory subunit PKARIα protects against myocardial ischemia-reperfusion injury by inhibiting lysosomal-triggered calcium release JN Simon, B Vrellaku, S Monterisi, SM Chu, N Rawlings, O Lomas, ... Circulation 143 (5), 449-465, 2021 | 35 | 2021 |
Chronically elevated branched chain amino acid levels are pro-arrhythmic V Portero, T Nicol, S Podliesna, GA Marchal, A Baartscheer, S Casini, ... Cardiovascular research 118 (7), 1742-1757, 2022 | 25 | 2022 |
Targeting the Microtubule EB1-CLASP2 Complex Modulates NaV1.5 at Intercalated Discs GA Marchal, M Jouni, DY Chiang, M Pérez-Hernández, S Podliesna, N Yu, ... Circulation research 129 (3), 349-365, 2021 | 22 | 2021 |
Absence of Functional Nav1.8 Channels in Non-diseased Atrial and Ventricular Cardiomyocytes S Casini, GA Marchal, M Kawasaki, FA Nariswari, V Portero, ... Cardiovascular Drugs and Therapy 33, 649-660, 2019 | 22 | 2019 |
A common co-morbidity modulates disease expression and treatment efficacy in inherited cardiac sodium channelopathy MR Rivaud, JA Jansen, PG Postema, EA Nannenberg, Y Mizusawa, ... European heart journal 39 (31), 2898-2907, 2018 | 21 | 2018 |
Optogenetic manipulation of cardiac electrical dynamics using sub-threshold illumination: dissecting the role of cardiac alternans in terminating rapid rhythms V Biasci, L Santini, GA Marchal, S Hussaini, C Ferrantini, R Coppini, ... Basic Research in Cardiology 117 (1), 25, 2022 | 20 | 2022 |
Patch-clamp recordings of action potentials from human atrial myocytes: optimization through dynamic clamp AO Verkerk, GA Marchal, JG Zegers, M Kawasaki, AHG Driessen, ... Frontiers in Pharmacology 12, 649414, 2021 | 19 | 2021 |
Subcellular diversity of Nav1. 5 in cardiomyocytes: distinct functions, mechanisms and targets GA Marchal, CA Remme The Journal of Physiology 601 (5), 941-960, 2023 | 14 | 2023 |
Functional modulation of atrio-ventricular conduction by enhanced late sodium current and calcium-dependent mechanisms in Scn5a1798insD/+ mice MR Rivaud, GA Marchal, R Wolswinkel, JA Jansen, I van der Made, ... EP Europace 22 (10), 1579-1589, 2020 | 13 | 2020 |
Functional Consequences of the SCN5A-p.Y1977N Mutation within the PY Ubiquitylation Motif: Discrepancy between HEK293 Cells and Transgenic Mice S Casini, M Albesa, Z Wang, V Portero, D Ross-Kaschitza, JS Rougier, ... International journal of molecular sciences 20 (20), 5033, 2019 | 13 | 2019 |
The sodium channel NaV1.5 impacts on early murine embryonic cardiac development, structure and function in a non‐electrogenic manner GA Marchal, AO Verkerk, RA Mohan, R Wolswinkel, BJD Boukens, ... Acta Physiologica 230 (2), e13493, 2020 | 10 | 2020 |
Desmosomal protein degradation as an underlying cause of arrhythmogenic cardiomyopathy H Tsui, SJ van Kampen, SJ Han, V Meraviglia, WB van Ham, S Casini, ... Science Translational Medicine 15 (688), eadd4248, 2023 | 9 | 2023 |
Low human dystrophin levels prevent cardiac electrophysiological and structural remodelling in a Duchenne mouse model GA Marchal, M van Putten, AO Verkerk, S Casini, K Putker, ... Scientific reports 11 (1), 9779, 2021 | 9 | 2021 |
Optogenetic manipulation of cardiac repolarization gradients using sub-threshold illumination GA Marchal, V Biasci, LM Loew, A Biggeri, M Campione, L Sacconi Frontiers in Physiology 14, 1167524, 2023 | 4 | 2023 |
Microtubule plus-end tracking proteins: novel modulators of cardiac sodium channels and arrhythmogenesis GA Marchal, N Galjart, V Portero, CA Remme Cardiovascular research 119 (7), 1461-1479, 2023 | 2 | 2023 |
Differential sodium current remodelling identifies distinct cellular proarrhythmic mechanisms in paroxysmal vs persistent atrial fibrillation S Casini, GA Marchal, M Kawasaki, B Fabrizi, R Wesselink, FA Nariswari, ... Canadian Journal of Cardiology 39 (3), 277-288, 2023 | 2 | 2023 |
Decreasing microtubule detyrosination modulates Nav1.5 subcellular distribution and restores sodium current in mdx cardiomyocytes G Nasilli, TM de Waal, GA Marchal, G Bertoli, MW Veldkamp, ... Cardiovascular Research, cvae043, 2024 | 1 | 2024 |
Impact of microtubule detyrosination on subcellular distribution of Nav1. 5 in mdx cardiomyocytes S Casini, G Nasilli, T De Waal, GA Marchal, E Rothenberg, M Delmar, ... European Heart Journal 44 (Supplement_2), ehad655. 3061, 2023 | 1 | 2023 |
Recent advances and current limitations of available technology to optically manipulate and observe cardiac electrophysiology GA Marchal, V Biasci, P Yan, C Palandri, M Campione, E Cerbai, ... Pflügers Archiv-European Journal of Physiology 475 (11), 1357-1366, 2023 | 1 | 2023 |
Decreasing microtubule detyrosination by parthenolide restores sodium current in mdx cardiomyocytes S Casini, G Nasilli, T De Waal, Y Dekkers, S Van Amersfoorth, ... Europace 25 (Supplement_1), euad122. 592, 2023 | 1 | 2023 |