Development of selective mono or dual PROTAC degrader probe of CDK isoforms F Zhou, L Chen, C Cao, J Yu, X Luo, P Zhou, L Zhao, W Du, J Cheng, ... European journal of medicinal chemistry 187, 111952, 2020 | 87 | 2020 |
Brain-targeting, acid-responsive antioxidant nanoparticles for stroke treatment and drug delivery S Zhang, B Peng, Z Chen, J Yu, G Deng, Y Bao, C Ma, F Du, WC Sheu, ... Bioactive materials 16, 57-65, 2022 | 25 | 2022 |
Discovery and biological evaluation of darolutamide derivatives as inhibitors and down-regulators of wild-type AR and the mutants J Yu, P Zhou, M Hu, L Yang, G Yan, R Xu, Y Deng, X Li, Y Chen European Journal of Medicinal Chemistry 182, 111608, 2019 | 19 | 2019 |
Targeted delivery of chemo‐sonodynamic therapy via brain targeting, glutathione‐consumable polymeric nanoparticles for effective brain cancer treatment H Wu, X Gao, Y Luo, J Yu, G Long, Z Jiang, J Zhou Advanced Science 9 (28), 2203894, 2022 | 18 | 2022 |
Synthesis and evaluation of novel thiazole‐based derivatives as selective inhibitors of DNA‐binding domain of the androgen receptor R Xu, Y Tian, S Huang, J Yu, Y Deng, M Zhan, T Zhang, F Wang, L Zhao, ... Chemical Biology & Drug Design 91 (1), 172-180, 2018 | 16 | 2018 |
Discovery and biological evaluation of novel androgen receptor antagonist for castration-resistant prostate cancer J Yu, L Zhang, G Yan, P Zhou, C Cao, F Zhou, X Li, Y Chen European Journal of Medicinal Chemistry 171, 265-281, 2019 | 14 | 2019 |
Design, synthesis and biological evaluation of deuterated Vismodegib for improving pharmacokinetic properties F Wang, H Jiang, Y Deng, J Yu, M Zhan, L Zhao, Y Chen Bioorganic & medicinal chemistry letters 28 (14), 2399-2402, 2018 | 11 | 2018 |
Novel thiohydantoin analogues bearing the 1-hydroxyl-2, 2, 2-trifluoro-1-ethyl moiety as androgen receptor inhibitors for the potential treatment of castration resistant … Y Wang, Y Deng, X Pang, J Yu, L Fan, Y Chen, L Zhao RSC advances 7 (51), 31866-31874, 2017 | 6 | 2017 |
Metabolically stable diphenylamine derivatives suppress androgen receptor and BET protein in prostate cancer J Yu, P Zhou, W Du, R Xu, G Yan, Y Deng, X Li, Y Chen Biochemical Pharmacology 177, 113946, 2020 | 5 | 2020 |
Microtubule signals J Yu, P Zhou, M Hu, L Yang, G Yan, R Xu, Y Deng, X Li, Y Chen | | |