ATF6 regulates cardiac hypertrophy by transcriptional induction of the mTORC1 activator, Rheb EA Blackwood, C Hofmann, M Santo Domingo, AS Bilal, A Sarakki, ... Circulation research 124 (1), 79-93, 2019 | 93 | 2019 |
Mesencephalic astrocyte–derived neurotrophic factor is an ER-resident chaperone that protects against reductive stress in the heart A Arrieta, EA Blackwood, WT Stauffer, M Santo Domingo, AS Bilal, ... Journal of Biological Chemistry 295 (22), 7566-7583, 2020 | 34 | 2020 |
ATF6 as a Nodal Regulator of Proteostasis in the Heart CC Glembotski, A Arrieta, EA Blackwood, WT Stauffer Frontiers in physiology 11, 527299, 2020 | 29 | 2020 |
The ER unfolded protein response effector, ATF6, reduces cardiac fibrosis and decreases activation of cardiac fibroblasts WT Stauffer, EA Blackwood, K Azizi, RJ Kaufman, CC Glembotski International journal of molecular sciences 21 (4), 1373, 2020 | 24 | 2020 |
Integrating ER and mitochondrial proteostasis in the healthy and diseased heart A Arrieta, EA Blackwood, WT Stauffer, CC Glembotski Frontiers in Cardiovascular Medicine 6, 193, 2020 | 23 | 2020 |
Designing novel therapies to mend broken hearts: ATF6 and cardiac proteostasis EA Blackwood, AS Bilal, WT Stauffer, A Arrieta, CC Glembotski Cells 9 (3), 602, 2020 | 12 | 2020 |
Sledgehammer to scalpel: broad challenges to the heart and other tissues yield specific cellular responses via transcriptional regulation of the ER-stress master regulator ATF6α WT Stauffer, A Arrieta, EA Blackwood, CC Glembotski International Journal of Molecular Sciences 21 (3), 1134, 2020 | 10 | 2020 |
MANF, A Structurally Unique Redox-Sensitive Chaperone, Restores ER Protein Folding in the Ischemic Heart. A Arrieta, EA Blackwood, WT Stauffer, M Santo Domingo, AN Pentoney, ... Circulation Research 121 (suppl_1), A2-A2, 2017 | 2 | 2017 |
MANF, a structurally unique ER stress-inducible protein, restores ER-protein folding in ER stressed cardiac Myocytes and in the ischemic heart A Arrieta, EA Blackwood, WT Stauffer, AN Pentoney, DJ Thuerauf, ... Circulation 134 (suppl_1), A19772-A19772, 2016 | 2 | 2016 |
Mice lacking cyclophilin B, but not cyclophilin A, are protected from the development of NASH in a diet and chemical-induced model WT Stauffer, AZ Goodman, M Bobardt, DR Ure, RT Foster, P Gallay Plos one 19 (3), e0298211, 2024 | 1 | 2024 |
The Cyclophilin Inhibitor Rencofilstat Decreases HCV-Induced Hepatocellular Carcinoma Independently of Its Antiviral Activity W Stauffer, M Bobardt, D Ure, R Foster, P Gallay Viruses 15 (10), 2099, 2023 | 1 | 2023 |
ATF6 and the adaptive ER stress response promotes proliferation and viability of mouse cardiac progenitor cells WT Stauffer, S Doroudgar, HN Stephens, B Bailey, CC Glembotski Circulation 132 (suppl_3), A18348-A18348, 2015 | 1 | 2015 |
Cyclophilin D knockout significantly prevents HCC development in a streptozotocin-induced mouse model of diabetes-linked NASH WT Stauffer, M Bobardt, DR Ure, RT Foster, P Gallay Plos one 19 (4), e0301711, 2024 | | 2024 |
Mice lacking Cyclophilin B, but not Cyclophilin A, are significantly protected from the development of major features of NAFLD/NASH in a diet and chemical-induced model W Stauffer, D Ure, R Foster, P Gallay Journal of Hepatology 78, S748, 2023 | | 2023 |
Cyclophilin inhibition with rencofilstat shifts the liver transcriptome and lipidome in preclinical models toward resolution of non-alcoholic steatohepatitis D Ure, W Stauffer, B Variya, L Haddon, P Mayo, P Gallay, R Foster Journal of Hepatology 78, S770, 2023 | | 2023 |
The Cyclophilin Inhibitor Rencofilstat Decreases HCV-induced Hepatocellular Carcinoma Independently of Its Antiviral Activity PA Gallay, W Stauffer, M Bobardt, D Ure, R Foster bioRxiv, 2023.08. 19.553982, 2023 | | 2023 |
CYCLOPHILIN B KNOCKOUT SIGNIFICANTLY LIMITS THE DEVELOPMENT OF LIVER FIBROSIS IN A DIET AND CHEMICAL-INDUCED MOUSE MODEL OF NAFLD/NASH WT Stauffer, D Ure, R Foster, P Gallay HEPATOLOGY 76, S792-S792, 2022 | | 2022 |
Rencofilstat, a pan-cyclophilin inhibitor, exerts diverse metabolic and transcriptional anti-tumor activities in a murine NASH-HCC model D Ure, J Kuo, W Stauffer, L Haddon, P Mayo, R Foster, P Gallay Journal of Hepatology 77, S660, 2022 | | 2022 |
Cyclophilin D knockout promotes cell death pathways in preventing HCC development in a streptozotocin-induced mouse model of diabetes-linked NASH W Stauffer, J Kuo, D Ure, R Foster, P Gallay Journal of Hepatology 77, S650, 2022 | | 2022 |
EFFECT of ASTODRIMER SODIUM AGAINST SARS-CoV-2 VARIANTS (Α, Β, Γ, Δ, Κ) in VITRO P Gallay, C Luscombe, W Stauffer, MD Bobardt, G Heery, A Castellarnau, ... Topics in Antiviral Medicine, 182-183, 2022 | | 2022 |