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Natasha Emmanuel
Natasha Emmanuel
Associate Director, Tesseract Medicines
Verified email at tesseractmed.com
Title
Cited by
Cited by
Year
N-cadherin/FGFR promotes metastasis through epithelial-to-mesenchymal transition and stem/progenitor cell-like properties
X Qian, A Anzovino, S Kim, K Suyama, J Yao, J Hulit, G Agiostratidou, ...
Oncogene 33 (26), 3411-3421, 2014
1422014
Purine nucleotide availability regulates mTORC1 activity through the Rheb GTPase
N Emmanuel, S Ragunathan, Q Shan, F Wang, A Giannakou, N Huser, ...
Cell reports 19 (13), 2665-2680, 2017
1042017
Amphiregulin is a critical downstream effector of estrogen signaling in ERα-positive breast cancer
EA Peterson, EC Jenkins, KA Lofgren, N Chandiramani, H Liu, E Aranda, ...
Cancer research 75 (22), 4830-4838, 2015
562015
Mutant GATA3 actively promotes the growth of normal and malignant mammary cells
N Emmanuel, KA Lofgren, EA Peterson, DR Meier, EH Jung, PA Kenny
Anticancer research 38 (8), 4435-4441, 2018
342018
Sustained mTORC1 activity during palbociclib-induced growth arrest triggers senescence in ER+ breast cancer cells
RS Maskey, F Wang, E Lehman, Y Wang, N Emmanuel, W Zhong, G Jin, ...
Cell Cycle 20 (1), 65-80, 2021
242021
VRK1 is a synthetic–lethal target in VRK2-deficient glioblastoma
JA Shields, SR Meier, M Bandi, EE Mulkearns-Hubert, N Hajdari, ...
Cancer Research 82 (21), 4044-4057, 2022
172022
Molecular basis for vulnerability to mitochondrial and oxidative stress in a neuroendocrine CRI-G1 cell line
N Chandiramani, X Wang, M Margeta
PLoS One 6 (1), e14485, 2011
102011
VRK1 is a paralog synthetic lethal target in VRK2-methylated glioblastoma
JA Shields, SR Meier, M Bandi, MD Ferdinez, JL Engel, ...
Biorxiv, 2021.12. 30.474571, 2022
22022
Abstract P2-04-06: Transgenic expression of a breast-cancer specific GATA3 mutant leads to mammary hyperplasia
PA Kenny, N Chandiramani
Cancer Research 72 (24_Supplement), P2-04-06-P2-04-06, 2012
22012
Comparative analysis of GATA3 mutation profiles between Asian and Western patients with breast cancer: Is there really a difference?
N Chandiramani, PA Kenny
Cancer (0008543X) 120 (17), 2014
12014
Abstract P182: VRK1 is a novel synthetic lethal target in VRK2-methylated glioblastoma
J Shields, SR Meier, J Engel, M Bandi, ML Dam Ferdinez, W Zhang, ...
Molecular Cancer Therapeutics 20 (12_Supplement), P182-P182, 2021
2021
Exploring the interplay between the purinosome, a multienzyme, purine biosynthetic machine, and the Rheb-mTORC1 signaling axis.
N Emmanuel, E Bernfeld, S Ragunathan, F Wang, Q Shan, A Giannakou, ...
MOLECULAR CANCER RESEARCH 18 (10), 34-34, 2020
2020
Abstract A10: Exploring the interplay between the purinosome, a multienzyme, purine biosynthetic machine, and the Rheb-mTORC1 signaling axis
N Emmanuel, E Bernfeld, S Ragunathan, F Wang, Q Shan, A Giannakou, ...
Molecular Cancer Research 18 (10_Supplement), A10-A10, 2020
2020
SAT-331 Elucidating the Role of Breast Cancer Specific GATA3 Mutation in Estrogen Receptor Positive Breast Cancer
K Lofgren, N Emmanuel, D Meier, P Kenny
Journal of the Endocrine Society 3 (Supplement_1), SAT-331, 2019
2019
Abstract B025: Purine biosynthesis regulates mTORC1 by modulating Rheb GTPase activity
K Unsal-Kacmaz, N Emmanuel, S Ragunathan, Q Shan, F Wang, ...
Molecular Cancer Therapeutics 17 (1_Supplement), B025-B025, 2018
2018
Abstract P1-08-02: Mutant GATA3 actively promotes the growth of normal and malignant mammary cells
PA Kenny, N Chandiramani, KA Lofgren
Cancer Research 77 (4_Supplement), P1-08-02-P1-08-02, 2017
2017
Functional Genomics Approaches to Elucidate the Role of Breast Cancer-Specific Mutations in GATA3
N Chandiramani, P Kenny
American Journal of Clinical Pathology 146 (suppl_1), 221, 2016
2016
Mutant GATA3 actively promotes the growth of normal and malignant mammary cells
N Chandiramani, E Peterson, PA Kenny
Cancer Research 76 (14_Supplement), 1991-1991, 2016
2016
Amphiregulin is a key effector of estrogen receptor in breast cancer
EA Peterson, N Chandiramani, EJ Aranda Jaque, EC Jenkins, PA Kenny
Cancer Research 75 (15_Supplement), 5046-5046, 2015
2015
Mutant GATA3 drives precocious lobuloalveolar mammary development and promotes the growth of estrogen receptor positive xenograft tumors
N Chandiramani, EA Peterson, EH Jung, EC Jenkins, PA Kenny
Cancer Research 75 (15_Supplement), 4197-4197, 2015
2015
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