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Xiaoqiang Huang
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Protein structure and sequence reanalysis of 2019-nCoV genome refutes snakes as its intermediate host and the unique similarity between its spike protein insertions and HIV-1
C Zhang, W Zheng, X Huang, EW Bell, X Zhou, Y Zhang
Journal of Proteome Research 19 (4), 1351-1360, 2020
3632020
De novo Design of Protein Peptides to Block Association of the SARS-CoV-2 Spike Protein with Human ACE2
X Huang, R Pearce, Y Zhang
Aging (Albany NY) 12 (12), 11263-11276, 2020
115*2020
Effects of SARSCoV2 mutations on protein structures and intraviral protein–protein interactions
S Wu, C Tian, P Liu, D Guo, W Zheng, X Huang, Y Zhang, L Liu
Journal of medical virology 93 (4), 2132-2140, 2020
1082020
EvoEF2: accurate and fast energy function for computational protein design
X Huang, R Pearce, Y Zhang
Bioinformatics 36, 1135–1142, 2020
842020
EvoDesign: Designing Protein–Protein Binding Interactions Using Evolutionary Interface Profiles in Conjunction with an Optimized Physical Energy Function
R Pearce, X Huang, D Setiawan, Y Zhang
Journal of molecular biology 431, 2467-2476, 2019
712019
FASPR: an open-source tool for fast and accurate protein side-chain packing
X Huang, R Pearce, Y Zhang
Bioinformatics 36 (12), 3758-3765, 2020
602020
Protein structure prediction using deep learning distance and hydrogenbonding restraints in CASP14
W Zheng, Y Li, C Zhang, X Zhou, R Pearce, EW Bell, X Huang, Y Zhang
Proteins: Structure, Function, and Bioinformatics, 2021
562021
SSIPe: accurately estimating protein–protein binding affinity change upon mutations using evolutionary profiles in combination with an optimized physical energy function
X Huang, W Zheng, R Pearce, Y Zhang
Bioinformatics 36 (8), 2429-2437, 2020
452020
Identifying the Zoonotic Origin of SARS-CoV-2 by Modeling the Binding Affinity between the Spike Receptor-Binding Domain and Host ACE2
X Huang, C Zhang, R Pearce, GS Omenn, Y Zhang
Journal of proteome research 19 (12), 4844-4856, 2020
382020
Systematic optimization model and algorithm for binding sequence selection in computational enzyme design
X Huang, K Han, Y Zhu
Protein Science 22 (7), 929-941, 2013
382013
Computational redesign of penicillin acylase for cephradine synthesis with high kinetic selectivity
J He, X Huang, J Xue, Y Zhu
Green Chemistry 20 (24), 5484-5490, 2018
332018
Recent Advances in Improving Gene-Editing Specificity through CRISPR–Cas9 Nuclease Engineering
X Huang, D Yang, J Zhang, J Xu, YE Chen
Cells 11 (14), 2186, 2022
292022
Computational design of variants for cephalosporin C acylase from Pseudomonas strain N176 with improved stability and activity
Y Tian, X Huang, Q Li, Y Zhu
Applied microbiology and biotechnology 101 (2), 621-632, 2017
242017
Computational design of enzyme–ligand binding using a combined energy function and deterministic sequence optimization algorithm
Y Tian, X Huang, Y Zhu
Journal of molecular modeling 21 (8), 1-14, 2015
242015
Computational design of SARS-CoV-2 spike glycoproteins to increase immunogenicity by T cell epitope engineering
E Ong, X Huang, R Pearce, Y Zhang, Y He
Computational and structural biotechnology journal, 2020
232020
Use of an improved matching algorithm to select scaffolds for enzyme design based on a complex active site model
X Huang, J Xue, M Lin, Y Zhu
PloS one 11 (5), e0156559, 2016
232016
Using molecular dynamics simulations to evaluate active designs of cephradine hydrolase by molecular mechanics/Poisson–Boltzmann surface area and molecular mechanics …
J Xue, X Huang, Y Zhu
RSC advances 9 (24), 13868-13877, 2019
212019
Computational design of cephradine synthase in a new scaffold identified from structural databases
X Huang, J Xue, Y Zhu
Chemical Communications 53 (54), 7604-7607, 2017
212017
Landscape of variable domain of heavychainonly antibody repertoire from alpaca
Z Tu, X Huang, J Fu, N Hu, W Zheng, Y Li, Y Zhang
Immunology 161 (1), 53-65, 2020
192020
Changing the apoptosis pathway through evolutionary protein design
D Shultis, P Mitra, X Huang, J Johnson, NA Khattak, F Gray, C Piper, ...
Journal of molecular biology 431 (4), 825-841, 2019
182019
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