| Neuronal activity modifies the chromatin accessibility landscape in the adult brain Y Su, J Shin, C Zhong, S Wang, P Roychowdhury, J Lim, D Kim, G Ming, ... Nature neuroscience 20 (3), 476-483, 2017 | 240 | 2017 |
| Orally bioavailable glutamine antagonist prodrug JHU-083 penetrates mouse brain and suppresses the growth of MYC-driven medulloblastoma AR Hanaford, J Alt, R Rais, SZ Wang, H Kaur, DLJ Thorek, CG Eberhart, ... Translational oncology 12 (10), 1314-1322, 2019 | 54 | 2019 |
| GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity DC Watson, D Bayik, S Storevik, SS Moreino, SA Sprowls, J Han, ... Nature cancer 4 (5), 648-664, 2023 | 39 | 2023 |
| Severe consequences of a high-lipid diet include hydrogen sulfide dysfunction and enhanced aggression in glioblastoma DJ Silver, GA Roversi, N Bithi, SZ Wang, KM Troike, CKA Neumann, ... The Journal of Clinical Investigation 131 (17), 2021 | 31 | 2021 |
| Sex-biased T-cell exhaustion drives differential immune responses in glioblastoma J Lee, M Nicosia, ES Hong, DJ Silver, C Li, D Bayik, DC Watson, A Lauko, ... Cancer discovery 13 (9), 2090-2105, 2023 | 25 | 2023 |
| Unbiased metabolic profiling predicts sensitivity of high MYC-expressing atypical teratoid/rhabdoid tumors to glutamine inhibition with 6-diazo-5-oxo-L-norleucine SZ Wang, B Poore, J Alt, A Price, SJ Allen, AR Hanaford, H Kaur, BA Orr, ... Clinical Cancer Research 25 (19), 5925-5936, 2019 | 24 | 2019 |
| The TORC1/2 inhibitor TAK228 sensitizes atypical teratoid rhabdoid tumors to cisplatin-induced cytotoxicity JA Rubens, SZ Wang, A Price, MF Weingart, SJ Allen, BA Orr, ... Neuro-oncology 19 (10), 1361-1371, 2017 | 22 | 2017 |
| Dual mTORC1/2 inhibition compromises cell defenses against exogenous stress potentiating Obatoclax-induced cytotoxicity in atypical teratoid/rhabdoid tumors A Parkhurst, SZ Wang, TR Findlay, KJ Malebranche, A Odabas, J Alt, ... Cell Death & Disease 13 (4), 410, 2022 | 5 | 2022 |
| Homeostatic iron regulatory protein drives glioblastoma growth via tumor cell-intrinsic and sex-specific responses KM Troike, SZ Wang, DJ Silver, J Lee, EE Mulkearns-Hubert, N Hajdari, ... Neuro-Oncology Advances 6 (1), vdad154, 2024 | | 2024 |
| Tumor cell-derived spermidine promotes a pro-tumorigenic immune microenvironment in glioblastoma via CD8+ T cell inhibition K Kay, J Lee, ES Hong, J Beilis, S Dayal, ER Wesley, S Mitchell, SZ Wang, ... bioRxiv, 2023.11. 14.567048, 2023 | | 2023 |
| Unbiased metabolic profiling of atypical teratoid/rhabdoid tumors predicts sensitivity to the glutamine metabolic inhibitor 6-diazo-5-oxo-L-norleucine SZ Wang, B Poore, J Alt, A Price, S Allen, B Orr, R Rais, B Slusher, ... Cancer Research 79 (13_Supplement), 5267-5267, 2019 | | 2019 |
| Disrupting glutamine metabolism depletes glutathione and sensitizes atypical teratoid/rhabdoid tumor to carboplatin SZ Wang, B Poore, J Alt, R Rais, S Allen, B Orr, B Slusher, C Eberhart, ... Cancer Research 78 (13_Supplement), 3519-3519, 2018 | | 2018 |
| ATRT-38. TAK228 COMBINES WITH NAVITOCLAX TO ENHANCE PLATINUM-INDUCED CYTOTOXICITY IN AT/RT J Rubens, S Wang, S Sharma, S Shah, K Warren, C Eberhart, E Raabe Neuro-Oncology 20 (Suppl 2), i36, 2018 | | 2018 |
| Targeting abnormal metabolism downstream of MYC in atypical teratoid/rhabdoid tumors S Wang, J Rubens, S Allen, B Orr, C Eberhart, E Raabe Cancer Research 77, 2017 | | 2017 |
| ATRT-08. TARGETING GLUTAMINE METABOLISM IN MYC DRIVEN ATYPICAL TERATOID RHABDOID TUMORS J Rubens, S Wang, A Price, S Allen, B Orr, C Eberhart, E Raabe Neuro-Oncology 19 (Suppl 4), iv2, 2017 | | 2017 |
charles eberhartProfessor of Pathology, Ophthalmology and Oncology, Johns Hopkins University School of MedicineVerified email at jhmi.edu
