| SEL120-34A is a novel CDK8 inhibitor active in AML cells with high levels of serine phosphorylation of STAT1 and STAT5 transactivation domains T Rzymski, M Mikula, E Żyłkiewicz, A Dreas, K Wiklik, A Gołas, K Wójcik, ... Oncotarget 8 (20), 33779, 2017 | 86 | 2017 |
| Effect of bisphenol-A on the expression of selected genes involved in cell cycle and apoptosis in the OVCAR-3 cell line A Ptak, A Wróbel, EL Gregoraszczuk Toxicology letters 202 (1), 30-35, 2011 | 84 | 2011 |
| Effects of single and repeated in vitro exposure of three forms of parabens, methyl-, butyl-and propylparabens on the proliferation and estradiol secretion in MCF-7 and MCF-10A … A Wróbel, E Gregoraszczuk Pharmacological Reports 65 (2), 484-493, 2013 | 67 | 2013 |
| Actions of methyl-, propyl-and butylparaben on estrogen receptor-α and-β and the progesterone receptor in MCF-7 cancer cells and non-cancerous MCF-10A cells AM Wróbel, EŁ Gregoraszczuk Toxicology letters 230 (3), 375-381, 2014 | 58 | 2014 |
| Action of methyl-, propyl-and butylparaben on GPR30 gene and protein expression, cAMP levels and activation of ERK1/2 and PI3K/Akt signaling pathways in MCF-7 breast cancer … AM Wróbel, EŁ Gregoraszczuk Toxicology Letters 238 (2), 110-116, 2015 | 51 | 2015 |
| Resistin is a survival factor for porcine ovarian follicular cells A Rak, E Drwal, A Wrobel, EŁ Gregoraszczuk Reproduction 150 (4), 343-355, 2015 | 43 | 2015 |
| Differential effect of methyl‐, butyl‐and propylparaben and 17β‐estradiol on selected cell cycle and apoptosis gene and protein expression in MCF‐7 breast cancer cells and MCF … AM Wróbel, EŁ Gregoraszczuk Journal of Applied Toxicology 34 (9), 1041-1050, 2014 | 43 | 2014 |
| Valproic acid, but not levetiracetam, selectively decreases HDAC7 and HDAC2 expression in human ovarian cancer cells P Kwiecińska, A Wróbel, E Taubøll, EŁ Gregoraszczuk Toxicology letters 224 (2), 225-232, 2014 | 27 | 2014 |
| Ghrelin negatively affects the function of ovarian follicles in mature pigs by direct action on basal and gonadotropin-stimulated steroidogenesis A Rak-Mardyła, A Wróbel, EL Gregoraszczuk Reproductive Sciences 22 (4), 469-475, 2015 | 23 | 2015 |
| Combinatory effects of PBDEs and 17β-estradiol on MCF-7 cell proliferation and apoptosis P Kwiecińska, A Wróbel, E Gregoraszczuk Pharmacological Reports 63 (1), 189-194, 2011 | 23 | 2011 |
| Hexachlorobenzene and pentachlorobenzene accumulation, metabolism and effect on steroid secretion and on CYP11A1 and CYP19 expression in cultured human placental tissue EL Gregoraszczuk, A Ptak, A Karpeta, E Fiedor, A Wróbel, T Milewicz, ... Reproductive Toxicology 43, 102-110, 2014 | 14 | 2014 |
| Evaluation of MDA-MB-468 cell culture media analysis in predicting triple-negative breast cancer patient sera metabolic profiles W Wojtowicz, A Wróbel, K Pyziak, R Tarkowski, A Balcerzak, M Bębenek, ... Metabolites 10 (5), 173, 2020 | 12 | 2020 |
| The ability of hydroxylated estrogens (2-OH-E2 and 4-OH-E2) to increase of SHBG gene, protein expression and intracellular levels in MCF-7 cells line EL Gregoraszczuk, A Ptak, A Wrobel Endocr Regul 45 (3), 125-130, 2011 | 8 | 2011 |
| IDH2 mutations in patients with normal karyotype AML predict favorable responses to daunorubicin, cytarabine and cladribine regimen M Libura, E Bialopiotrowicz, S Giebel, A Wierzbowska, GJ Roboz, ... Scientific reports 11 (1), 10017, 2021 | 6 | 2021 |
| Hydroxylated estrogens (2-OH-E2 AND 4-OH-E2) do not activate cAMP/PKA and ERK1/2 pathways activation in a breast cancer MCF-7 cell line P Kwiecinska, A Ptak, A Wrobel, EL Gregoraszczuk Endocr. Regul 46, 3-12, 2012 | 6 | 2012 |
| Discovery of novel SHMT small molecule inhibitors for cancer treatment A Bartosik, P Guzik, M Sowinska, K Gluza, M Król, A Wróbel, A Dreas, ... Proc AACR Annual Meeting 2018, 2018 | 2 | 2018 |
| Development of novel, selective SMARCA2 (BRM) degraders for treatment of SMARCA4 (BRG1) mutated tumors A Mazan, A Wróbel, A Dreas, A Radzimierski, K Michalik, A Kowal, ... Cancer Research 80 (16), 2020 | 1 | 2020 |
| Small molecule inhibitors of SHMT1/2 validate serine metabolism as a target in the treatment of c-Myc positive solid tumors T Rzymski, A Wrobel, K Pyziak, A Sroka, M Sowinska, A Dreas, M Krol, ... Cancer Research 77 (13_Supplement), 442-442, 2017 | 1 | 2017 |
| Epigenetic modulators show differential activity on lung adenocarcinoma cells with loss-of-function mutations of SWI/SNF protein SMARCA4 T Rzymski, A Wrobel, M Mikula, K Pyziak, A Bartosik, A Sroka, ... Cancer Research 77 (13_Supplement), 5063-5063, 2017 | 1 | 2017 |
| SEL120–34A, a specific, potent and orally bioavailable inhibitor of CDK8, targets STAT-dependent gene transcription in leukemia and lymphoma models E Zylkiewicz, T Rzymski, M Mikula, A Dreas, K Wiklik, A Wrobel, A Golas, ... European Journal of Cancer 1 (69), S132, 2016 | 1 | 2016 |
